Asunto(s)
Biorretroalimentación Psicológica/métodos , Microftalmía/rehabilitación , Segmento Posterior del Ojo/patología , Enfermedades de la Retina/rehabilitación , Baja Visión/rehabilitación , Pruebas del Campo Visual/métodos , Niño , Femenino , Fijación Ocular , Humanos , Microftalmía/fisiopatología , Educación del Paciente como Asunto , Enfermedades de la Retina/diagnóstico , Enfermedades de la Retina/fisiopatología , Tomografía de Coherencia Óptica , Baja Visión/diagnóstico , Baja Visión/fisiopatología , Campos Visuales/fisiologíaRESUMEN
OBJECTIVE: To assess the safety and efficacy of combined cataract extraction, posterior chamber intraocular lens placement, pars plana vitrectomy, fluocinolone acetonide intravitreal implant (Retisert), and Ahmed valves with pars plana tube (CPR-PT) in eyes with chronic, posterior, noninfectious uveitis. METHODS: Retrospective study of patients who underwent CPR-PT. Outcome measures included visual acuity, intraocular pressure, inflammation, and complications. RESULTS: Eight eyes were included, with a mean follow-up of 18 months. Mean visual acuity improved from 1.89 to 0.14 logMAR (Snellen, counting fingers at 2 ft [0.6 m]) to 20/30; P=.01). Mean intraocular pressure remained stable at 16 to 17 mm Hg (P=.35). The number of glaucoma medications per eye decreased from 2.9 to 0.25 (P=.01). Systemic prednisone therapy was discontinued in all patients by 9 months postoperatively. Inflammation was well controlled in all eyes. CONCLUSION: The CPR-PT procedure allows rapid visual rehabilitation without major short-term complications.
Asunto(s)
Extracción de Catarata , Implantes de Medicamentos , Fluocinolona Acetonida/administración & dosificación , Implantes de Drenaje de Glaucoma , Implantación de Lentes Intraoculares , Uveítis Posterior/complicaciones , Vitrectomía , Adulto , Anestesia Local , Antihipertensivos/administración & dosificación , Catarata/complicaciones , Catarata/terapia , Enfermedad Crónica , Femenino , Estudios de Seguimiento , Glaucoma/complicaciones , Glaucoma/cirugía , Humanos , Presión Intraocular/fisiología , Masculino , Persona de Mediana Edad , Segmento Posterior del Ojo , Complicaciones Posoperatorias , Estudios Retrospectivos , Esclerostomía , Técnicas de Sutura , Resultado del Tratamiento , Uveítis Posterior/tratamiento farmacológico , Agudeza Visual/fisiología , Cuerpo Vítreo/efectos de los fármacosRESUMEN
AIM: To evaluate the effects of orally administered black-currant (BC) extract on the enlargement of globe component dimensions induced in chicks by wearing negative lenses. METHODS: Negative lenses (-8 D) were worn on the right eyes by 8-day-old chicks, and their fellow eyes acted as controls. BC extract and distilled water (vehicle control) were orally administered once a day for 3 days. To confirm the effect of BC anthocyanins (BCAs), they were intravenously administered once a day for 3 days. Dimensions of globe components of right eyes and fellow eyes were measured with an A-scan ultrasound instrument on the third day (day 4) after placement of the negative lenses. RESULTS: Orally administered BC extract significantly inhibited enlargement of vitreous-chamber depth, axial and ocular lengths in a dose-dependent manner when compared to controls. Intravenously administered BCAs also inhibited elongation of vitreous-chamber depth and axial length when compared to controls. CONCLUSIONS: This is the first evidence that BC extract and BCAs could inhibit enlargement of globe component dimensions in a negative lens-induced chick myopia model.