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1.
Nat Rev Dis Primers ; 3: 17018, 2017 Apr 27.
Artículo en Inglés | MEDLINE | ID: mdl-28447605

RESUMEN

Traumatic spinal cord injury (SCI) has devastating consequences for the physical, social and vocational well-being of patients. The demographic of SCIs is shifting such that an increasing proportion of older individuals are being affected. Pathophysiologically, the initial mechanical trauma (the primary injury) permeabilizes neurons and glia and initiates a secondary injury cascade that leads to progressive cell death and spinal cord damage over the subsequent weeks. Over time, the lesion remodels and is composed of cystic cavitations and a glial scar, both of which potently inhibit regeneration. Several animal models and complementary behavioural tests of SCI have been developed to mimic this pathological process and form the basis for the development of preclinical and translational neuroprotective and neuroregenerative strategies. Diagnosis requires a thorough patient history, standardized neurological physical examination and radiographic imaging of the spinal cord. Following diagnosis, several interventions need to be rapidly applied, including haemodynamic monitoring in the intensive care unit, early surgical decompression, blood pressure augmentation and, potentially, the administration of methylprednisolone. Managing the complications of SCI, such as bowel and bladder dysfunction, the formation of pressure sores and infections, is key to address all facets of the patient's injury experience.


Asunto(s)
Traumatismos de la Médula Espinal/complicaciones , Traumatismos de la Médula Espinal/etiología , Heridas y Lesiones/complicaciones , Terapia por Estimulación Eléctrica/métodos , Glucocorticoides/farmacología , Glucocorticoides/uso terapéutico , Humanos , Hipotensión/etiología , Hipotensión/fisiopatología , Imagen por Resonancia Magnética/métodos , Metilprednisolona/farmacología , Metilprednisolona/uso terapéutico , Calidad de Vida/psicología , Radiografía/métodos , Traumatismos de la Médula Espinal/fisiopatología , Columna Vertebral/anatomía & histología , Columna Vertebral/inervación , Siringomielia/etiología , Tomografía Computarizada por Rayos X/métodos , Heridas y Lesiones/cirugía
2.
J Manipulative Physiol Ther ; 28(6): 452, 2005.
Artículo en Inglés | MEDLINE | ID: mdl-16096046

RESUMEN

OBJECTIVE: To present a case of a 41-year-old man with syringomyelia and intractable pain and the subsequent reduction of symptoms. CLINICAL FEATURES: This patient acquired a traumatically induced syrinx in his upper cervical spinal cord after he fell approximately 9 feet and landed on his head, upper back, and neck 9 years before presenting for care. He was diagnosed with a spinal cord cyst (syrinx), located at approximately C2 through C4 after magnetic resonance imaging. In 1995, the patient underwent occipitoatlantal decompression surgery, which improved his symptoms for a short time. INTERVENTION AND OUTCOMES: The patient was treated using Clinical Biomechanics of Posture protocol. The patient was seen 26 times over the course of 3 weeks. His scale for pain severity decreased 50% and other subjective complaints decreased. His posture improved based upon pretreatment and posttreatment lateral cervical radiographs, showing a change from a 10 degrees lordosis with midcervical kyphosis to a 30 degrees lordosis. One-year follow-up examination showed stable improvement in the cervical lordosis and pain intensity. CONCLUSION: This case represents a change in subjective and objective measurements after conservative chiropractic care. This case provides an example that structural rehabilitation may have a positive effect on symptoms of a patient with syringomyelia.


Asunto(s)
Manipulación Quiropráctica , Dolor Intratable/terapia , Siringomielia/rehabilitación , Accidentes por Caídas , Adulto , Vértebras Cervicales/diagnóstico por imagen , Vértebras Cervicales/patología , Humanos , Lordosis/diagnóstico por imagen , Lordosis/etiología , Imagen por Resonancia Magnética , Masculino , Dimensión del Dolor , Dolor Intratable/etiología , Dolor Intratable/fisiopatología , Postura , Radiografía , Siringomielia/diagnóstico , Siringomielia/etiología , Resultado del Tratamiento , Heridas y Lesiones/complicaciones
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