RESUMEN
This article presents the background for including phytopreparation Alba (root extract of the Potentilla alba) into complex treatment of thyroid pathology. The findings confirm visible reduction of size of the thyroid gland and normalizing its functions in children and adults with the thyroid gland with normal or enhanced function treated by Alba per oral.
Asunto(s)
Bocio Endémico/tratamiento farmacológico , Bocio Nodular/tratamiento farmacológico , Hipotiroidismo/tratamiento farmacológico , Extractos Vegetales/uso terapéutico , Potentilla/química , Tiroiditis Autoinmune/tratamiento farmacológico , Tirotoxicosis/tratamiento farmacológico , Administración Oral , Adolescente , Niño , Femenino , Bocio Endémico/patología , Bocio Nodular/patología , Humanos , Hipotiroidismo/patología , Masculino , Tamaño de los Órganos/efectos de los fármacos , Extractos Vegetales/aislamiento & purificación , Raíces de Plantas/química , Glándula Tiroides/efectos de los fármacos , Glándula Tiroides/patología , Tiroiditis Autoinmune/patología , Tirotoxicosis/patologíaAsunto(s)
Medicamentos Herbarios Chinos/efectos adversos , Glándula Tiroides/efectos de los fármacos , Tirotoxicosis/inducido químicamente , Adulto , Fármacos Antiobesidad/efectos adversos , Suplementos Dietéticos/efectos adversos , Medicamentos Herbarios Chinos/química , Femenino , Humanos , Glándula Tiroides/patología , Tirotoxicosis/patología , Privación de TratamientoRESUMEN
High prevalence of hyperplastic and autoimmune diseases of thyroid in Ukrainian population is determined by endemic deficit of iodine and selenium. The aim of this research was to assess the place of biologically-active additions on the basis of herbal material containing an iodine and selenium in prophylaxis and treatment of thyroid pathology. During the six month period 55 patients received herbal preparation Alba twice a day. The levels of TSH, volume of thyroid, the sizes of nodular goiter (ultrasound investigation) were measured before and at the end of the investigation. The levels of thyroid stimulating antibodies to TSH receptor (AB-r TSH) were evaluated in patients with hyperthyroidism. The results of Alba application showed that in patients with thyroid pathology (diffuse nontoxic goiter, hyperthyroidism and chronic thyroiditis) it was possible to reduce the volume of thyroid, normalize its function, and decrease the level of AB-r TSH in diffuse toxic goiter. We also found approximately 20 % shortening of the time needed to get target level of TSH and finally the duration of treatment of thyrotoxicosis.
Asunto(s)
Bocio Nodular/tratamiento farmacológico , Enfermedad de Graves/tratamiento farmacológico , Hipertiroidismo/tratamiento farmacológico , Fitoterapia , Extractos Vegetales/farmacología , Potentilla/química , Tirotoxicosis/tratamiento farmacológico , Adulto , Femenino , Bocio Nodular/metabolismo , Bocio Nodular/patología , Enfermedad de Graves/metabolismo , Enfermedad de Graves/patología , Humanos , Hipertiroidismo/metabolismo , Hipertiroidismo/patología , Inmunoglobulinas Estimulantes de la Tiroides/sangre , Yodo/deficiencia , Masculino , Extractos Vegetales/aislamiento & purificación , Selenio/deficiencia , Glándula Tiroides/efectos de los fármacos , Glándula Tiroides/metabolismo , Glándula Tiroides/patología , Tirotoxicosis/metabolismo , Tirotoxicosis/patología , Tirotropina/sangre , UcraniaRESUMEN
O bócio multinodular (BMN) é definido como um aumento da glândula tireóide secundário à proliferação multifocal de tireócitos e caracteriza-se pela heterogeneidade no crescimento e função das células foliculares. O BMN é considerado uma neoplasia benigna da tireóide. É uma doença comum, com aumento da prevalência em áreas com deficiência de iodo, sendo este o principal fator etiológico ambiental. A patogênese desta disfunção tireoidiana ainda não está inteiramente elucidada. Nesta revisão serão abordados os principais mecanismos envolvidos na patogênese, seguidos das implicações clínicas dessa patologia.
Multinodular goiter (MNG) is defined as an enlargement of the thyroid gland that is characterized by heterogeneity in growth and function of thyroid follicular cells. MNG is now considered a true thyroid neoplasm. It is a common disease, with higher prevalences in iodine deficiency areas. Iodine deficiency is the main environmental etiologic factor for MNG. The pathogenesis of multinodular goiter is not yet fully clarified. The purpose of this review is to summarize the current knowledge of MNG with respect to the pathology, etiologic and clinical characteristics.
Asunto(s)
Humanos , Niño , Adolescente , Bocio/complicaciones , Bocio/congénito , Bocio/diagnóstico , Bocio/etiología , Bocio/genética , Bocio/patología , Diagnóstico Clínico , Deficiencia de Yodo/complicaciones , Deficiencia de Yodo/diagnóstico , Deficiencia de Yodo/etiología , Deficiencia de Yodo/metabolismo , Tirotoxicosis/etiología , Tirotoxicosis/genética , Tirotoxicosis/patologíaRESUMEN
This article describes three patients who developed factitious thyrotoxicosis, as well as other adverse effects, after taking herbal dietary supplements for weight reduction. All products were found to contain undeclared animal thyroid tissue and western pharmaceuticals causing the adverse effects. Adulteration is concealed addition of undeclared drugs, or other substances with therapeutic effects, to a health product. Consumption of such products, and the concealed components unwittingly, is obviously dangerous. Multiple adulterants in one product are often seen. Untoward adverse effect or drug interaction could occur. Overdose subsequent to poor standardization of the adulterants is another concern. Health care professionals must therefore be aware of the potential dangers posed by adulterated dietary supplements.