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1.
Sci Rep ; 13(1): 19299, 2023 11 07.
Artigo em Inglês | MEDLINE | ID: mdl-37935858

RESUMO

The aim of this study was to investigate the ability of shell (coating) formulations comprised of alginate and glucono delta lactone (GDL) to encapsulate a mixture of green tea and turmeric extracts. Three concentrations of alginate and GDL were used at 0.5%, 0.75%, and 1%, w/v and their solid ratio was varied using a factorial design. A response surface model was applied to optimize the retention of catechin and curcuminoid contents, to determine encapsulation efficiency, and to minimize undesirable flavor and taste. Increasing the concentration of alginate and GDL significantly increased the retention of catechin and curcuminoid contents, encapsulation efficiency, and consumer acceptance (p < 0.05). The encapsulating solution containing 1% of each alginate and GDL performed the best against each criterion. The thermal treatment carried out at the boiling point of water for 15 min had a significant impact on the retention of catechin and curcuminoid content which, in the thermally-treated beads, was 5.15 and 3.85 times higher than unencapsulated, respectively. The consumer acceptance of the encapsulated beads after thermal treatment was higher than that of the unencapsulated formulations as they exhibited lesser pungent flavor and bitterness. The innovative process of thermally stable microencapsulation can produce anti-cancer activity compounds involved in functional food industrial sectors.


Assuntos
Catequina , Chá , Curcuma , Alginatos , Diarileptanoides
2.
Food Chem ; 402: 134149, 2023 Feb 15.
Artigo em Inglês | MEDLINE | ID: mdl-36155289

RESUMO

This study investigated the potential of yeast extract and radio frequency (RF) treatment as a strategy of reducing salt and enhancing saltiness perception for Lentinus edodes bud. The results of E-nose demonstrated yeast extract and RF treatment improved the saltiness of Lentinus edodes bud. Meanwhile, yeast extract and RF treatment significantly decreased the addition of salt (P < 0.05), and led to the formation of special flavor substances, whereas amino acid nitrogen content decreased. On the other hand, sensory attribute, hardness, total flavonoid and phenolic content, antioxidant capacity of L. edodes buds significantly (P < 0.05) increased after the yeast extract combined with RF treatment. In addition, the modification of water distribution, the formation of dense structure, uniform microstructure and Na+ distribution were observed in treated sample, causing the enhancement of saltiness perception. Accordingly, the alteration of properties contributed to higher sensory properties of texture, taste, flavor, and overall acceptability.


Assuntos
Cogumelos Shiitake , Cogumelos Shiitake/química , Antioxidantes , Cloreto de Sódio na Dieta , Cloreto de Sódio , Flavonoides , Água/química , Percepção , Aminoácidos , Nitrogênio
3.
Crit Rev Food Sci Nutr ; 63(27): 8975-8991, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-35416723

RESUMO

Nostoc sphaeroides is an edible Cyanobacterium which has high nutritional value and is widely used in dietary supplements and therapeutic products. N. sphaeroides contains protein, fatty acid, minerals and vitamins. Its polysaccharides, phycobilin, phycobiliproteins and some lipids are highly bioactive. Thus, N. sphaeroides possesses anti-oxidation, anti-inflammation and cholesterol reducing functions. This paper reviews and evaluates the literature on nutritionally and functionally important compounds of N. sphaeroides. It also reviews and evaluates the processing of technologies used to process N. sphaeroides from fresh harvest to dry particulates including pretreatment, sterilization and drying, including their impact on sensorial and nutritional values. This review shows that a suitable combination of ultrasound, radio frequency and pulse spouted microwave with traditional sterilization and drying technologies greatly improves the sensorial and nutritive quality of processed N. sphaeroides and improves their shelf life; however, further research is needed to evaluate these hybrid technologies. Once suitably processed, N. sphaeroides can be used in food, cosmetics and pharmaceutical drugs as an ingredient.


Assuntos
Nostoc , Suplementos Nutricionais/análise , Colesterol , Dessecação
4.
Crit Rev Food Sci Nutr ; 62(16): 4504-4525, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-33506686

RESUMO

About one-third of the world population is suffering from iron deficiency. Delivery of iron through diet is a practical, economical, and sustainable approach. Clinical studies have shown that the consumption of iron-fortified foods is one of the most effective methods for the prevention of iron deficiency. However, supplementing iron through diet can cause undesirable side-effects. Thus, it is essential to develop new iron-rich ingredients, iron-fortified products with high bioavailability, better stability, and lower cost. It is also essential to develop newer processing technologies for more effective fortification. This review compared the iron supplementation strategies used to treat the highly iron-deficient population and the general public. We also reviewed the efficacy of functional (iron-rich) ingredients that can be incorporated into food materials to produce iron-fortified foods. The most commonly available foods, such as cereals, bakery products, dairy products, beverages, and condiments are still the best vehicles for iron fortification and delivery.Scope of reviewThe manuscript aims at providing a comprehensive review of the latest publications that cover three aspects: administration routes for iron supplementation, iron-rich ingredients used for iron supplementation, and iron-fortified foods.


Assuntos
Deficiências de Ferro , Ferro , Dieta , Suplementos Nutricionais , Alimentos Fortificados , Humanos
5.
Int J Mol Sci ; 22(17)2021 Aug 31.
Artigo em Inglês | MEDLINE | ID: mdl-34502362

RESUMO

Finding an effective therapeutic to prevent or cure AD has been difficult due to the complexity of the brain and limited experimental models. This study utilized unmodified and genetically modified Saccharomyces cerevisiae as model organisms to find potential natural bioactive compounds capable of reducing intracellular amyloid beta 42 (Aß42) and associated oxidative damage. Eleven natural bioactive compounds including mangiferin, quercetin, rutin, resveratrol, epigallocatechin gallate (EGCG), urolithin A, oleuropein, rosmarinic acid, salvianolic acid B, baicalein and trans-chalcone were screened for their ability to reduce intracellular green fluorescent protein tagged Aß42 (GFP-Aß42) levels. The two most effective compounds from the screens were combined in varying concentrations of each to study the combined capacity to reduce GFP-Aß42. The most effective combinations were examined for their effect on growth rate, turnover of native Aß42 and reactive oxygen species (ROS). The bioactive compounds except mangiferin and urolithin A significantly reduced intracellular GFP-Aß42 levels. Baicalein and trans-chalcone were the most effective compounds among those that were screened. The combination of baicalein and trans-chalcone synergistically reduced GFP-Aß42 levels. A combination of 15 µM trans-chalcone and 8 µM baicalein was found to be the most synergistic combination. The combination of the two compounds significantly reduced ROS and Aß42 levels in yeast cells expressing native Aß42 without affecting growth of the cells. These findings suggest that the combination of baicalein and trans-chalcone could be a promising multifactorial therapeutic strategy to cure or prevent AD. However, further studies are recommended to look for similar cytoprotective activity in humans and to find an optimal dosage.


Assuntos
Doença de Alzheimer/metabolismo , Chalcona/farmacologia , Flavanonas/farmacologia , Doença de Alzheimer/tratamento farmacológico , Doença de Alzheimer/fisiopatologia , Peptídeos beta-Amiloides/efeitos dos fármacos , Peptídeos beta-Amiloides/metabolismo , Chalcona/metabolismo , Avaliação Pré-Clínica de Medicamentos/métodos , Flavanonas/metabolismo , Humanos , Modelos Biológicos , Estresse Oxidativo/efeitos dos fármacos , Estresse Oxidativo/fisiologia , Fragmentos de Peptídeos/efeitos dos fármacos , Fragmentos de Peptídeos/metabolismo , Substâncias Protetoras/farmacologia , Espécies Reativas de Oxigênio/metabolismo , Saccharomyces cerevisiae/metabolismo , Proteínas de Saccharomyces cerevisiae/metabolismo
6.
J Integr Med ; 19(4): 300-310, 2021 07.
Artigo em Inglês | MEDLINE | ID: mdl-33863692

RESUMO

Parkinson's disease (PD) is a chronic progressive neurodegenerative disease. It results from the death of dopaminergic neurons. The pathophysiological mechanisms in idiopathic PD include the production of α-synuclein and mitochondrial respiratory function-affecting complex I, caused by reactive oxygen species. Therefore, the use of natural antioxidants in PD may provide an alternative therapy that prevents oxidative stress and reduces disease progression. In this review, the effects of hydroxytyrosol, Ginkgo biloba, Withania somnifera, curcumin, green tea, and Hypericum perforatum in PD animal and cell line models are compared and discussed. The reviewed antioxidants show evidence of protecting neural cells from oxidative stress in animal and cell models of PD. However, the clinical efficacy of these phytochemicals needs to be optimised and further investigated.


Assuntos
Doenças Neurodegenerativas , Doença de Parkinson , Animais , Antioxidantes/farmacologia , Linhagem Celular , Modelos Animais de Doenças , Modelos Animais , Estresse Oxidativo , Doença de Parkinson/tratamento farmacológico
7.
Int J Mol Sci ; 20(20)2019 Oct 14.
Artigo em Inglês | MEDLINE | ID: mdl-31615073

RESUMO

Ageing is an inevitable fundamental process for people and is their greatest risk factor for neurodegenerative disease. The ageing processes bring changes in cells that can drive the organisms to experience loss of nutrient sensing, disrupted cellular functions, increased oxidative stress, loss of cellular homeostasis, genomic instability, accumulation of misfolded protein, impaired cellular defenses and telomere shortening. Perturbation of these vital cellular processes in neuronal cells can lead to life threatening neurological disorders like Alzheimer's Disease, Parkinson's Disease, Huntington's Disease, Lewy body dementia, etc. Alzheimer's Disease is the most frequent cause of deaths in the elderly population. Various therapeutic molecules have been designed to overcome the social, economic and health care burden caused by Alzheimer's Disease. Almost all the chemical compounds in clinical practice have been found to treat symptoms only limiting them to palliative care. The reason behind such imperfect drugs may result from the inefficiencies of the current drugs to target the cause of the disease. Here, we review the potential role of antioxidant polyphenolic compounds that could possibly be the most effective preventative strategy against Alzheimer's Disease.


Assuntos
Doença de Alzheimer/dietoterapia , Antioxidantes/uso terapêutico , Doença de Huntington/dietoterapia , Doença de Parkinson/dietoterapia , Polifenóis/uso terapêutico , Idoso , Doença de Alzheimer/metabolismo , Antioxidantes/metabolismo , Homeostase , Humanos , Doença de Huntington/metabolismo , Neurônios/efeitos dos fármacos , Estresse Oxidativo/efeitos dos fármacos , Doença de Parkinson/metabolismo , Polifenóis/metabolismo , Espécies Reativas de Oxigênio/metabolismo
8.
Food Chem ; 275: 457-466, 2019 Mar 01.
Artigo em Inglês | MEDLINE | ID: mdl-30724220

RESUMO

In this study, chia seed oil (CSO) microcapsules were produced using three types of shell materials, including chia seed protein (CPI), chia seed gum (CSG) and CPI-CSG complex coacervates. Synchrotron-Fourier transform infrared (S-FTIR) microspectroscopy was used to investigate the effect of shell materials on the distribution of CSO both on the surface and in the interior of the solid microcapsules. S-FTIR measurements were carried out in macroscopic attenuated total reflection (macro ATR) and transmission modes, to determine the surface lipid and the encapsulated lipid fractions, respectively. The amounts of lipid and protein distributed on the surface and in the interior of the microcapsules were compared based on the average spectra extracted from S-FTIR chemical images obtained from each type of the microcapsules. The unsaturated fatty acids (UFAs) to total oil ratios in all the three types of the microcapsules were closely similar to the original non-processed CSO, suggesting an effective encapsulation and thereby shielding protection of UFAs from oxidative damage during microencapsulation process. The type of the shell materials was found to affect the distribution of CSO on the surface and within the microcapsules. The complex coacervation based microcapsules had a significantly lower oil content (∼2% w/w) on the surface compared to those observed for the other two types of microcapsules (>5%, w/w).


Assuntos
Óleos de Plantas/química , Salvia/química , Sementes/química , Espectroscopia de Infravermelho com Transformada de Fourier/instrumentação , Síncrotrons , Cápsulas/química , Oxirredução
9.
Crit Rev Food Sci Nutr ; 59(3): 450-461, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-28920702

RESUMO

Plant byproducts of food processing industry line are undervalued yet important resource. These byproducts contain large percentage of high value functional substances such as antioxidants, pectin, polyphenols and so on. Recently, many research studies concentrated on innovative technologies that promise to overcome such issues as time consuming, inefficiency, and low yield, among others, which exist in most conventional techniques. Consequently, to achieve the recovery of nutraceuticals from high added-value by-products, it is necessary to have more knowledge of these novel technologies and more importantly explore the possibility of application of these latest technologies to the recovery downstream processing. The present work will summarize state-of-the-art technological approaches concerning extraction, superfine and drying applied to plant food processing residues. Simultaneously, the application of the bioactive components originated from byproducts in food industry will also be reviewed.


Assuntos
Indústria de Processamento de Alimentos/tendências , Compostos Fitoquímicos/isolamento & purificação , Plantas Comestíveis/química , Antioxidantes , Dessecação , Manipulação de Alimentos/métodos , Indústria de Processamento de Alimentos/métodos , Resíduos Industriais/análise , Micro-Ondas , Tamanho da Partícula , Pectinas , Extratos Vegetais/química , Polifenóis
10.
Crit Rev Food Sci Nutr ; 59(4): 580-596, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-28933602

RESUMO

Lactoferrin (LF) is a multifunctional protein occurring in many biological secretions including milk. It possesses iron binding/transferring, antibacterial, antiviral, antifungal, anti-inflammatory and anti-carcinogenic properties. These functional properties intimately depend on the structural integrity of LF especially its higher order conformation. LF is primarily extracted from bovine milk and it is subsequently added into many commercial products such as nutritional supplements, infant formula, cosmetics and toothpaste. LF is sensitive to denaturation induced by temperature and other physicochemical stresses. Hence, the extraction, powder formation processes of LF and processing parameters of LF-containing products have to be optimized to minimise its undesired denaturation. This review documents the advances made on structure-function relationships and discusses the effectiveness of methods used to preserve the structure of LF during thermal processing. Oral delivery, as the most convenient way for administering LF, is also discussed focusing on digestion of LF in oral, gastric and intestinal stages. The effectiveness of methods used to deliver LF to intestinal digestion stage in structurally intact form is also compared. Altogether, this work comprehensively reviews the fate of LF during thermal processing and digestion, and suggests suitable means to preserve its structural integrity and functional properties. Scope of review The manuscript aims at providing a comprehensive review of the latest publications on four aspects of LF: structural features, functional properties, nature and extent of denaturation and gastrointestinal digestion. It also analyses how these publications benefit food and pharmaceutical industries.


Assuntos
Digestão , Lactoferrina/química , Lactoferrina/fisiologia , Leite/química , Desnaturação Proteica , Animais , Antibacterianos , Anti-Inflamatórios , Antifúngicos , Antivirais , Sítios de Ligação , Bovinos , Fenômenos Químicos , Estabilidade de Medicamentos , Manipulação de Alimentos/métodos , Temperatura Alta , Humanos , Concentração de Íons de Hidrogênio , Ferro/metabolismo , Lactoferrina/administração & dosagem , Modelos Moleculares , Estrutura Molecular
11.
J Sci Food Agric ; 98(5): 1719-1724, 2018 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-28858376

RESUMO

BACKGROUND: Nostoc sphaeroides has been used as a highly effective herbal medicine and dietary supplement for thousands of years. The desired dark green colour of fresh N. sphaeroides is converted into an undesirable dark brown during conventional high pressure (HP) steam sterilisation. Radio frequency (RF) sterilisation technology was used in this study to determine its effectiveness in sterilising N. sphaeroides and to achieve better preservation of natural colour and desirable flavour. Sterilisation was carried out using a 6 kW, 27 MHz RF instrument for 10, 20 and 30 min. The degree of microbial kill and the effects of RF sterilisation on colour and flavour were determined and compared with those obtained from HP steam (121 °C, 30 min) sterilisation. RESULTS: The effects of RF sterilisation on colour and flavour (measured using electronic nose) parameters were significantly lower than that in HP steam sterilisation. The RF sterilisation carried out for 20 min achieved logarithmic reduction of bacterial population and met China's national standard while preserving the colour and flavour better. CONCLUSION: Results of the present study indicated that application of RF sterilisation would improve the quality of sterilised N. sphaeroides and broaden its application in the food and health food industries. © 2017 Society of Chemical Industry.


Assuntos
Fatores Biológicos/isolamento & purificação , Aromatizantes/isolamento & purificação , Manipulação de Alimentos/métodos , Nostoc/química , Fatores Biológicos/química , Cor , Suplementos Nutricionais/análise , Aromatizantes/química , Humanos , Nostoc/efeitos da radiação , Pressão , Controle de Qualidade , Ondas de Rádio , Vapor/análise , Esterilização , Paladar
12.
Food Chem ; 228: 394-402, 2017 Aug 01.
Artigo em Inglês | MEDLINE | ID: mdl-28317740

RESUMO

Physicochemical and thermal characteristics of Australian chia seed oil (CSO) were studied. The specific gravity, viscosity and refractive index of CSO at ambient temperature were 0.93, 43.2mPa.s and 1.48, respectively. The acid, peroxide, saponification and iodine values and unsaponifiable matter content of CSO were 2.54gKOH/kg oil, 4.33meqO2/kg oil, 197gKOH/kg oil, 204gI2/kg oil and 1.12%, respectively. α-linolenic acid is the most abundant fatty acid comprising (64.39% of total oil) followed by linoleic acid (21.46%), while saturated fatty acid content is less than 10%. This CSO contained twelve triacylglycerols (TAGs) out of which trilinolenin (αLnαLnαLn) was the most abundant comprising 33.2% of total TAG. Melting point and melting enthalpy of CSO were -34°C and 77.48J/g, respectively. CSO remained stable up to 300°C with negligible degradation. Due to these physicochemical and thermal properties, CSO is an excellent source of essential fatty acids for food industries.


Assuntos
Ácidos Graxos/química , Óleos de Plantas/química , Salvia/química , Sementes/química , Fenômenos Químicos , Ácidos Graxos/análise
13.
Int J Biol Macromol ; 91: 347-57, 2016 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-27212219

RESUMO

Chia seed oil (CSO) microcapsules were produced by using chia seed protein isolate (CPI)-chia seed gum (CSG) complex coacervates aiming to enhance the oxidative stability of CSO. The effect of wall material composition, core-to-wall ratio and method of drying on the microencapsulation efficiency (MEE) and oxidative stability (OS) was studied The microcapsules produced using CPI-CSG complex coacervates as wall material had higher MEE at equivalent payload, lower surface oil and higher OS compared to the microcapsules produced by using CSG and CPI individually. CSO microcapsules produced by using CSG as wall material had lowest MEE (67.3%) and oxidative stability index (OSI=6.6h), whereas CPI-CSG complex coacervate microcapsules had the highest MEE (93.9%) and OSI (12.3h). The MEE and OSI of microcapsules produced by using CPI as wall materials were in between those produced by using CSG and CPI-CSG complex coacervates as wall materials. The CSO microcapsules produced by using CPI-CSG complex coacervate as shell matrix at core-to-wall ratio of 1:2 had 6 times longer storage life compared to that of unencapsulated CSO. The peroxide value of CSO microcapsule produced using CPI-CSG complex coacervate as wall material was <10meq O2/kg oil during 30 days of storage.


Assuntos
Óleos de Plantas/química , Proteínas de Plantas/química , Salvia/química , Sementes/química , Cápsulas
14.
Carbohydr Polym ; 102: 136-43, 2014 Feb 15.
Artigo em Inglês | MEDLINE | ID: mdl-24507265

RESUMO

Cellulose nanofibers (diameter=10-70 nm) were produced using chemical treatments (alkali treatment and bleaching) and high pressure homogenization from de-pectinated sugar beet pulp (DSBP). Chemical analysis and Fourier transform infrared spectroscopy (FTIR) indicated that the chemical treatments greatly removed the hemicellulose and lignin from the DSBP and significantly increased the cellulose content. The crystallinity of the cellulose nanofibers increased from 35.67% to 69.62% after alkali treatment and bleaching. The thermal degradation temperature of DSBP cellulose nanofibers was 271.7 °C which was found to be 47.3 °C higher than that of the untreated DSBP. The DSBP cellulose nanofibers can be preferably used as reinforcement in the biocomposite material at high temperature.


Assuntos
Beta vulgaris/química , Celulose/química , Nanofibras/química , Pectinas/isolamento & purificação , Microscopia Eletrônica de Varredura , Espectroscopia de Infravermelho com Transformada de Fourier , Termogravimetria , Difração de Raios X
15.
Carbohydr Polym ; 95(1): 233-40, 2013 Jun 05.
Artigo em Inglês | MEDLINE | ID: mdl-23618265

RESUMO

A central composite design was employed to determine the optimum extraction condition to obtain higher yield, better color attribute as well as better rheological and emulsifying properties in pectin extracted from sugar beet pulp (SBP). A second-order polynomial model was developed for predicting the yield of sugar beet pulp pectin (SBPP) based on the composite design. Response surface methodology (RSM) was used to quantify the integral effect of three processing parameters (extraction temperature, time and pH) on yield, yield stress, color attribute (tint value) and emulsifying activity index (EAI). Through the frequency analysis it was found that the optimal temperature, time and pH value of the extraction were 93.7 °C, 3 h, and 1.21, respectively. The yield, yield stress and tint value of the SBPP extracted at the optimal condition were 24.45%, above 0.1 Pa and -6.0, respectively.


Assuntos
Beta vulgaris/química , Modelos Estatísticos , Pectinas/química , Cor , Concentração de Íons de Hidrogênio , Pectinas/isolamento & purificação , Temperatura , Fatores de Tempo
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