Assuntos
Hipertensão Arterial Pulmonar , Humanos , Exercícios Respiratórios , Aconselhamento , MúsculosRESUMO
Diuretic therapy is a cornerstone in the management of heart failure. Most studies assessing body thiamine status have reported variable degrees of thiamine deficiency in patients with heart failure, particularly those treated chronically with high doses of furosemide. Thiamine deficiency in patients with heart failure seems predominantly to be due to increased urine volume and urinary flow rate. There is also evidence that furosemide may directly inhibit thiamine uptake at the cellular level. Limited data suggest that thiamine supplementation is capable of increasing left ventricular ejection fraction and improving functional capacity in patients with heart failure and a reduced left ventricular ejection fraction who were treated with diuretics (predominantly furosemide). Therefore, it may be reasonable to provide such patients with thiamine supplementation during heart failure exacerbations.
Assuntos
Furosemida/efeitos adversos , Insuficiência Cardíaca/tratamento farmacológico , Inibidores de Simportadores de Cloreto de Sódio e Potássio/efeitos adversos , Deficiência de Tiamina/induzido quimicamente , Tiamina/uso terapêutico , Complexo Vitamínico B/uso terapêutico , Suplementos Nutricionais , Insuficiência Cardíaca/fisiopatologia , Humanos , Volume Sistólico , Deficiência de Tiamina/tratamento farmacológico , Resultado do Tratamento , Função Ventricular EsquerdaRESUMO
Percutaneous coronary revascularization is rarely complicated by infection. Necrotizing fasciitis (NF) is a severe, deep-seated, potentially life-threatening infection of fascia and subcutaneous tissues. We report herein 2 cases of NF in patients undergoing percutaneous transluminal coronary revascularization for treatment of acute coronary syndrome. These are the first 2 reported cases of NF associated with percutaneous coronary revascularization.