Buschke-Ollendorff syndrome--differential diagnosis of disseminated connective tissue lesions.

We report a 5-year-old boy presenting with multiple elastic type nevi and osteopoikilosis who was diagnosed as having Buschke-Ollendorff syndrome at an early age. Connective tissue lesions may present as the main symptom of varying clinical entities with different outcomes. Differential diagnosis includes papular elastorrhexis, fibroelastolytic papules of the neck, papular acne scars, and late onset focal dermal elastosis. Rare genodermatoses, i.e. Buschke-Ollendorff syndrome, pseudoxanthoma elasticum, juvenile hyaline fibromatosis and familiar cutaneous collagenoma should be carefully evaluated to provide appropriate genetic counseling and to avoid unnecessary treatment procedures.

[Behavior of staphylococci of the nasal cavity in subjects exposed to hyperbaric oxygen]. / Comportamento degli stafilococchi delle cavità nasali di soggetti esposti ad ossigeno iperbarico.

A careful qualitative and quantitative study revealed a significant decrease in bacterial, and especially staphylococcal, cultures from nasal swabs 24 hr after exposure to oxygen at 2.5 atm for 30', followed by a gradual return to initial values after a further four days. It is felt that this picture was ascribable to the influence of hyperbaric O2 on the microorganisms and their metabolism, and on the body's defence mechanisms.

[Changes in the pharyngeal bacterial flora during hyperbaric oxygenation]. / Modificazioni della flora batterica faringea in corso di ossigenoterapia iperbarica.

Qualitative and quantitative bacteriological tests of throat smears were carried out on the following three groups of patients: 1) Patients exposed to several 90-minute sequences of oxygen hyperbaria, at a height of 2.2 ata O2, at intervals of 2 to 3 days. 2) Patients exposed to a single 30-minute dose of oxygen hyperbaria at a height of 2.5 ata O2/the oxygen test. 3) Patients who had never been exposed to oxygen hyperbaria. Several hundred bacterials strains of the Streptococcus, Staphylococcus, Klebsiella and Nocardia genus were isolated from the material collected from the tested patients over intervals of a few days. The collected samples were when subjected to a detailed bacteriological analysis. At the same time bacteriological tests were performed at intervals on the hyperbaric atmosphere of the therapeutic pressure chamber, the walls of the chamber, and the masks used by the patients during the administration of hyperbaric oxygen. A certain degree of qualitative and quantitative changes (number reduction of bacterial strains) was observed. The authors attribute these results to the influence of hyperbaric oxygenation both on the microorganisms, as well as on a given patient's reactivity.