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Technol Health Care ; 25(4): 651-655, 2017 Aug 09.
Artigo em Inglês | MEDLINE | ID: mdl-28436403

RESUMO

One major challenge of bioprinting is to develop a viable bioink to act as an extracellular matrix. This study investigated a novel method for bioprinting using a pectin based bioink. Besides pectin, Pluronic® F-127 was incorporated into the bioink to obtain the desired shape during the initial bioprinting process at 37∘C. Once an object was printed it was treated with Ca2+ (pectin cross-linker) to create the final tissue/organ structure. The results indicated that pectin/Pluronic® F-127 is a potential bioink. Moreover, this methodology provides a novel and fast approach for bioprinting.


Assuntos
Bioimpressão/métodos , Matriz Extracelular , Pectinas/química , Alicerces Teciduais , Cálcio/química , Cátions Bivalentes , Humanos , Poloxâmero/química
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