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Métodos Terapêuticos e Terapias MTCI
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1.
J Vasc Interv Radiol ; 27(3): 383-7, 2016 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-26806692

RESUMO

PURPOSE: To evaluate technical details, clinical outcomes, and complications in patients undergoing geniculate artery embolization for treatment of spontaneous hemarthrosis after knee surgery. MATERIALS AND METHODS: During 2009-2014, 10 consecutive patients (seven women; mean age, 57.4 y) underwent geniculate artery embolization at a single tertiary care center. All patients except one had hemarthrosis after total knee replacement (TKR). One patient presented with hemarthrosis after cartilage surgery. Two patients in the TKR group had a history of TKR revisions before the embolization. Embolization was performed with polyvinyl alcohol particles (range, 300-700 µm). In one patient requiring repeat embolization, N-butyl cyanoacrylate/ethiodized oil was used. The endpoint for embolization was stasis in the target artery and elimination of the hyperemic blush. RESULTS: In 10 patients, 14 embolizations were performed with 100% technical success. Hemarthrosis resolved in six patients. Four patients required repeat embolization for recurrent hemarthrosis, which subsequently resolved in two of four patients. Three of the four patients who required repeat embolization had serious comorbidities, either blood dyscrasias or therapeutic anticoagulation. There were two minor skin complications that resolved with conservative management. The average length of follow-up after embolization was 545 days (range, 50-1,655 d). One patient was lost to follow-up. CONCLUSIONS: Geniculate artery embolization is a safe, minimally invasive treatment option for spontaneous and refractory knee hemarthrosis after knee surgery with 100% technical success. However, limited clinical success and higher repeat embolization rates were noted in patients with serious comorbidities.


Assuntos
Artérias , Artroplastia do Joelho/efeitos adversos , Embolização Terapêutica/métodos , Hemartrose/terapia , Articulação do Joelho/irrigação sanguínea , Articulação do Joelho/cirurgia , Adolescente , Idoso , Angiografia Digital , Artérias/diagnóstico por imagem , Embolização Terapêutica/efeitos adversos , Embucrilato/administração & dosagem , Óleo Etiodado/administração & dosagem , Feminino , Hemartrose/diagnóstico , Hemartrose/etiologia , Humanos , Masculino , Pessoa de Meia-Idade , Álcool de Polivinil/administração & dosagem , Recidiva , Retratamento , Estudos Retrospectivos , Fatores de Risco , Fatores de Tempo , Resultado do Tratamento
2.
Clin Orthop Relat Res ; 468(1): 127-34, 2010 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-19669849

RESUMO

UNLABELLED: Prophylactic antibiotics are frequently withheld until cultures are obtained in revision total knee arthroplasty (TKA). We undertook a prospective study to determine whether prophylactic preoperative intravenous antibiotics would affect the results of cultures obtained intraoperatively. We enrolled 25 patients with 26 infected TKAs, a known preoperative infecting organism, and no recent antibiotic therapy. Reaspiration of the infected TKA was performed after anesthesia and sterile preparation. Intravenous antibiotic prophylaxis was then administered and the tourniquet inflated. Intraoperative culture swabs and tissue were obtained at arthrotomy. The timing of events was recorded. Pre- and postantibiotic culture data were analyzed to determine the effect of intravenous preoperative prophylactic antibiotics on cultures obtained intraoperatively. Infections were acute postoperative (four), chronic (19), and acute hematogenous (three). The most common infecting organism was cloxacillin-sensitive Staphylococcus aureus (nine knees [35%]). Preoperative prophylactic antibiotics did not affect the results of intraoperative cultures and we therefore believe should not be withheld before surgery for an infected TKA when an organism has been identified on aspiration preoperatively, and there has been no recent (4 weeks) antimicrobial therapy. LEVEL OF EVIDENCE: Level II, diagnostic study. See Guidelines for Authors for a complete description of levels of evidence.


Assuntos
Antibacterianos/uso terapêutico , Antibioticoprofilaxia , Artroplastia do Joelho/efeitos adversos , Cefazolina/uso terapêutico , Infecções Relacionadas à Prótese/tratamento farmacológico , Vancomicina/uso terapêutico , Idoso , Idoso de 80 Anos ou mais , Técnicas Bacteriológicas , Feminino , Humanos , Injeções Intravenosas , Período Intraoperatório , Masculino , Testes de Sensibilidade Microbiana , Pessoa de Meia-Idade , Estudos Prospectivos , Infecções Relacionadas à Prótese/microbiologia , Infecções Estafilocócicas/tratamento farmacológico , Staphylococcus aureus/efeitos dos fármacos
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