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1.
J Environ Radioact ; 118: 105-12, 2013 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-23295620

RESUMO

Distribution of uranium (VI) between soil solids and solutions is a key parameter in assessing the risk to the biosphere of disposing uranium-rich waste products from nuclear plants as well as uranium (U) ore mining. Both of these topics have recently been brought to public attention in Mongolia. Regional background levels of soil elements are an important dataset for accessing the actual environmental situation and monitoring pollution levels. Little information, however, is available on background concentrations of various elements in Mongolian soils. Thirteen rural soils were sampled from six provinces in Mongolia, and the concentrations of macro-, micro- and trace elements were measured. The values obtained served as a reference (baseline) for uncontaminated soils. The soils were characterized with slightly acidic to strongly alkaline pH values. With the exception of the sample from a western province, all the soils investigated contained little organic matter. The content of soil elements did not vary widely among geographical regions. The concentration of most micro elements was within the range of worldwide soil values but the value for Zn tended to be moderately higher. The U (VI) sorption into the soils was investigated using the batch technique and the (237)U radionuclide tracer, produced by the photo fission reaction (238)U(γ, n) (237)U at an electron accelerator. The (237)U distribution coefficient (K(d)), derived from the sorption isotherms, was related to solution pH and varying from 9 to 2547 mL g(-1) when the pH ranged between 3 and 7.7. The sorption process was interpreted in terms of the formation of different U (VI) species at given concentrations, calculated using the Speciation program with and without carbonate in the system. The U sorption isotherm displayed two general patterns: one where sorption decreased as solution pH increased, showing a maximum at pH 3, and another pattern revealed an adsorption maximum at pH 5 and then decreased up to pH 7.7 (the final solution pH). The observed decrease in K(d) when solution pH increased from 6 to 8 was consistent with the increased formation of soluble UO(2)(OH)(2) species. A linear negative correlation between lgK(d) and the solution pH was observed similarly to that reported for the soils with a pH ≥ 6.


Assuntos
Poluentes Radioativos do Solo/análise , Urânio/análise , Mongólia
2.
Artigo em Russo | MEDLINE | ID: mdl-24640658

RESUMO

The present review describes the modern methods for the combined treatment and rehabilitation of the patients presenting with arterial hypertension and their influence on the key pathogenetic components of this condition in accordance with the currently accepted theories of its origin and evolution. The discovery of specific molecular and cellular mechanisms of the therapeutic action of certain factors that reflect peculiar and unique character of their inherent physical energy provided a basis for the development of highly effective methods for the treatment and prevention of arterial hypertension and rehabilitation of the patients suffering this disease. The most comprehensive clinical effect is produced by the application of scientifically sound therapeutic systems; exclusion of certain therapeutic physical factors from these modalities results in s significant reduction of their curative effectiveness.


Assuntos
Hipertensão/prevenção & controle , Hipertensão/reabilitação , Humanos , Hipertensão/etiologia , Terapia com Luz de Baixa Intensidade , Magnetoterapia , Modalidades de Fisioterapia , Ensaios Clínicos Controlados Aleatórios como Assunto , Reflexoterapia , Resultado do Tratamento
3.
Artigo em Russo | MEDLINE | ID: mdl-21381322

RESUMO

The objective of the present work was to develop methods and a scientifically sound rationale for the optimization of clinical results of the treatment of patients presenting with arterial hypertension (AH) associated with coronary heart disease (CHD) using red and infra-red (IR) low-intensity laser irradiation. The study included a total of 90 patients of working age (62.2% of men and 37.8% of women) having AH associated with coronary heart disease and abnormal blood lipid spectrum. They were allocated to three groups each comprising 30 patients matched for age, sex, severity of clinical conditions, and character of maintenance medicamental therapy. Patients of group 1 were treated by intravenous blood irradiation with laser light; those in group 2 were given similar treatment in combination with external low-intensity IR laser therapy; patients of group 3 received basal medicamental therapy. The study allowed the clinical value of different variants of low-intensity laser therapy to be assessed as regards efficiency of correction of hypersympaticotony, disturbances of lipid metabolism, and refractoriness to pharmaceutical products as well as improved tolerance of physical exercises, anti-hypertensive, anti-ischemic, and anti-anginal effects, diastolic function, and quality of life as targets of the comprehensive rehabilitative program designed for patients with AH associated with coronary heart disease. An optimized therapeutic modality is proposed for patients presenting with these pathologies based on the application of the low-intensity laser irradiation regime characterized by mutual amplification and complementary action of red and infrared lights.


Assuntos
Procedimentos Endovasculares/métodos , Hipertensão/radioterapia , Terapia com Luz de Baixa Intensidade , Isquemia Miocárdica/radioterapia , Terapia Combinada , Feminino , Humanos , Hipertensão/sangue , Hipertensão/complicações , Hipertensão/tratamento farmacológico , Lipídeos/sangue , Masculino , Isquemia Miocárdica/sangue , Isquemia Miocárdica/complicações , Isquemia Miocárdica/tratamento farmacológico , Resultado do Tratamento
4.
Vopr Onkol ; 54(4): 507-11, 2008.
Artigo em Russo | MEDLINE | ID: mdl-18942411

RESUMO

An evaluation of the results of radiofrequency ablation of renal clear-cell carcinoma (pT1aN0M0) in 7 patients is presented. The longest follow-up was 26 months, the shortest--4 months. No complication was reported. A review of the literature and our own experience point to radiofrequency ablation being an effective procedure of thermotherapy for small-size peripheral renal neoplasms.


Assuntos
Carcinoma de Células Renais/cirurgia , Ablação por Cateter , Neoplasias Renais/cirurgia , Adulto , Carcinoma de Células Renais/patologia , Feminino , Seguimentos , Humanos , Neoplasias Renais/patologia , Masculino , Pessoa de Meia-Idade , Estadiamento de Neoplasias , Resultado do Tratamento
5.
Anesteziol Reanimatol ; (2): 68-73, 2006.
Artigo em Russo | MEDLINE | ID: mdl-16758950

RESUMO

A clinical case of successful use of 4% modified liquid gelatin (Helofusin, B. Braun, Germany) at a single-stage infusion volume of 4.5 liters (!) is described in a neurosurgical patient with the single during removal of a giant parietooccipal tumor complicated by rapid massive operative blood loss. The paper discusses the side effects of artificial colloidal infusion solutions, namely their effects on hemostasis and the status of viscera.


Assuntos
Perda Sanguínea Cirúrgica/prevenção & controle , Neoplasias Encefálicas/cirurgia , Carcinoma de Células Renais/cirurgia , Adulto , Transfusão de Sangue Autóloga , Neoplasias Encefálicas/irrigação sanguínea , Neoplasias Encefálicas/secundário , Carcinoma de Células Renais/irrigação sanguínea , Carcinoma de Células Renais/secundário , Angiografia Cerebral , Embolização Terapêutica , Gelatina/administração & dosagem , Hemodiluição , Humanos , Neoplasias Renais/patologia , Neoplasias Renais/cirurgia , Masculino , Nefrectomia , Substitutos do Plasma/administração & dosagem , Succinatos/administração & dosagem , Tomografia Computadorizada por Raios X
6.
Acta Otolaryngol ; 120(2): 214-7, 2000 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-11603775

RESUMO

It is evident that the conventional technique for cochlear implant adjustment is not suitable for children in their first years of life. In order to find a solution to this problem, the possibility of electrically evoked auditory brainstem response (EABR) recording was investigated. EABRs were recorded in 9 patients with the Nucleus multichannel cochlear implant. The main problems that have to be solved during EABR recording in cochlear implantees are: i) EABR distortion due to the stimulus artefact: and ii) difference in the stimulus presentation rate during EABR registration (low pulse rate) and conventional psychophysical threshold estimation (high pulse rate) in cochlear implant patients. The influence of stimulus artefact on the recording results was minimized by setting the implant to the widest amplifier frequency band and by zeroing the initial segment containing the stimulus artefact with subsequent zero-phase digital filtering. The dependence of the EABR amplitude and latency on the stimulus intensity, width, electrode location and interstimulus interval was investigated. It was concluded that despite the difference revealed between absolute values of EABR thresholds and psychophysical threshold levels, it is possible to calculate implant adjustment parameters based on the EABR data with the proper correction applied.


Assuntos
Núcleo Coclear , Surdez/reabilitação , Potenciais Evocados Auditivos do Tronco Encefálico/fisiologia , Estimulação Acústica , Adolescente , Adulto , Artefatos , Limiar Auditivo/fisiologia , Tronco Encefálico/fisiopatologia , Criança , Surdez/fisiopatologia , Análise de Falha de Equipamento , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Distorção da Percepção/fisiologia , Psicoacústica
7.
Artigo em Russo | MEDLINE | ID: mdl-8059565

RESUMO

In 2-3 weeks after the oral immunization of rabbits, made in one or two administrations, with attenuated two-marker S. dysenteriae 1 strain VS-12 and recombinant S. dysenteriae VS-12/S. sonnei NR-18 and S. flexneri y433/S. sonnei NR-18 pronounced immunological reaction developed in the mucous membrane of the small intestine: blast transformation follicles of Peyer's patches, an increase in the number of lymphoblasts and plasmocytes in the cupolae of follicles and in intestinal villi, and an increase in the number of lymphocytes and macrophages in the intestinal epithelium with their release into the lumen of the intestine after challenge with virulent shigellae. The protective potency of these recombinants after challenge with massive doses of virulent shigellae was found to be high, which was shown by quantitative evaluation of the decrease of adhesion, invasiveness and cytotoxicity, suppression of epithelial lesions and development of inflammation in the intestinal mucosa.


Assuntos
Vacinas Bacterianas/imunologia , Disenteria Bacilar/patologia , Disenteria Bacilar/prevenção & controle , Shigella dysenteriae/imunologia , Shigella flexneri/imunologia , Shigella sonnei/imunologia , Animais , Avaliação Pré-Clínica de Medicamentos , Disenteria Bacilar/imunologia , Imunização , Imunogenética , Intestino Delgado/imunologia , Intestino Delgado/patologia , Coelhos , Recombinação Genética , Shigella dysenteriae/genética , Shigella dysenteriae/patogenicidade , Shigella flexneri/genética , Shigella flexneri/patogenicidade , Shigella sonnei/genética , Shigella sonnei/patogenicidade , Fatores de Tempo , Vacinas Atenuadas/imunologia , Virulência
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