Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 2 de 2
Filtrar
Mais filtros

Base de dados
Ano de publicação
Tipo de documento
Intervalo de ano de publicação
1.
Tunis Med ; 95(1): 19-22, 2017 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-29327764

RESUMO

Idiopathic or Bell's palsy is an acute peripheral-nerve palsy involving the facial nerve. The disorder is quite infrequent under the age of 10 years. The proposed etiologies of Bell's palsy include ischemic neuropathy and vascular diseases. This case series presents five children with Bell's palsy. The epidemiologic, diagnostic and therapeutic measures were summarized. The evolution regarding especially the facial motricity was detailed. The results about the role of some thrombophilic polymorphisms suggest a probable involvement of factor V haplotype, MTHFR and factor XIII in the etiology of Bell's palsy in five Tunisian children.


Assuntos
Paralisia de Bell/diagnóstico , Paralisia de Bell/terapia , Aciclovir/administração & dosagem , Substituição de Aminoácidos/genética , Paralisia de Bell/genética , Criança , Pré-Escolar , Estudos de Coortes , Análise Mutacional de DNA , Fator V/genética , Fator XIII/genética , Feminino , Humanos , Hidrocortisona/administração & dosagem , Lactente , Masculino , Metilenotetra-Hidrofolato Redutase (NADPH2)/genética , Manipulações Musculoesqueléticas/métodos , Polimorfismo de Nucleotídeo Único , Indução de Remissão , Trombofilia/complicações , Trombofilia/genética
2.
Tunis Med ; 94(12): 863, 2016 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-28994886

RESUMO

INTRODUCTION: Necrotizing otitis externa remains a severe and sometimes life-threatening disease in diabetic patient. Many therapeutic approaches have been described but what about the real benefit of hyperbaric oxygenotherapy in the management of this disease? METHODS: The authors reported a retrospective study about 42 patients treated for necrotizing external otitis over a period of 9 years (2006 to 2014). The patients were treated either by only antibiotherapy (23 cases) or with both antibiotherapy and hyperbaric oxygenotherapy (19 cases). The evolution under treatment was appreciated in the two groups through clinical, biological and radiological parameters. RESULTS: The study included 42 diabetic patients with a mean age of 67 years (50 to 84 years). The sex-ratio M/F was 0.82. The diagnosis of necrotizing otitis externa was assessed through clinical and bacteriologic criteria in diabetic patients. A temporal bone CT-scan and a technetium scintigraphy were performed in order to precise the topography of the disease and the level of bone lysis. Antibiotherapy was prescribed intravenously and then orally for a mean period of 8 weeks (5 to 15 weeks). Hyperbaric oxygenotherapy was given for 19 patients (average: 20 sessions). The recovery was affirmed on clinical, biological and radiological features. Otalgia disappeared at the 11th day of treatment without HOT and at the 5th day with HOT. Otorrhea disappeared at the 6th day of treatment by HOT and at the 13th day without HOT. The recovery or the regression of facial palsy occurred in 75% of the cases when HOT was given. The total recovery from the disease was diagnosed in 36 patients (86%). The rate of recovery was 100% in the group treated by HOT and 74% in the group treated by only antibiotics. The recurrence of the disease was noted in 6 patients that haven't benefited from HOT. The end of the oral therapy was guided by the results of the Gallium bone scintigraphy. CONCLUSION: Hyperbaric oxygenotherapy must be associated in the treatment of necrotizing otitis externa. The results of our study suggest a real benefit of this therapy regarding clinical, biological and radiological parameters of this severe affection.


Assuntos
Complicações do Diabetes/terapia , Oxigenoterapia Hiperbárica , Otite Externa/terapia , Idoso , Idoso de 80 Anos ou mais , Antibacterianos/uso terapêutico , Terapia Combinada/métodos , Complicações do Diabetes/patologia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Necrose/terapia , Otite Externa/patologia , Estudos Retrospectivos , Tomografia Computadorizada por Raios X , Resultado do Tratamento
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA