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Voen Med Zh ; 337(7): 25-33, 2016 07.
Artigo em Russo | MEDLINE | ID: mdl-30590889

RESUMO

On selection of external bleeding models for preclinical evaluation of the effectiveness of local haemostatic agents (literature review). To temporarily stop of external bleeding traditionally use a pressure bandage or tourniquet, but not for all types of wounds it is possible and appropriate to apply these dressings. In recent times there has been significant progress in the development and improvement of local haemostatic agents used for the first aid. There are currently conflicting information about their effectiveness, presented by various authors, requires standardization of experimental modelsforpre-clinical testing of medical devices in this class. Following a review of domestic and foreign literature DroDosed to standardize external bleeding model for assessing the effectiveness of local haemostatic agents.


Assuntos
Modelos Animais de Doenças , Hemorragia/tratamento farmacológico , Técnicas Hemostáticas , Hemostáticos/uso terapêutico , Animais , Avaliação Pré-Clínica de Medicamentos/métodos , Hemorragia/patologia , Hemorragia/fisiopatologia , Humanos
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