RESUMO
BACKGROUND: Migraine is a complex and multifactorial brain disorder affecting approximately 18% of women and 5% of men in the United States, costing billions of dollars annually in direct and indirect healthcare costs and school and work absenteeism and presenteeism. Until this date, there have been no medications that were designed with the specific purpose to decrease the number of migraine attacks, which prompts a search for alternative interventions that could be valuable, such as acupuncture. METHODS: Acupuncture origins from ancient China and encompasses procedures that basically involve stimulation of anatomical points of the body. RESULTS: This manuscript reviews large and well-designed trials of acupuncture for migraine prevention and also the effectiveness of acupuncture when tried against proven migraine preventative medications. CONCLUSION: Acupuncture seems to be at least as effective as conventional drug preventative therapy for migraine and is safe, long lasting, and cost-effective. It is a complex intervention that may prompt lifestyle changes that could be valuable in patients' recovery.
Assuntos
Terapia por Acupuntura , Transtornos de Enxaqueca/prevenção & controle , Feminino , Flunarizina/uso terapêutico , Frutose/análogos & derivados , Frutose/uso terapêutico , Humanos , Masculino , Transtornos de Enxaqueca/tratamento farmacológico , Fármacos Neuroprotetores/uso terapêutico , Ensaios Clínicos Controlados Aleatórios como Assunto , Fatores de Tempo , TopiramatoRESUMO
BACKGROUND: Several factors, including the use of antiepileptic drugs, glucocorticoids, anticoagulants, chemotherapy, radiation therapy, and hemiplegia-associated osteopenia, render patients with brain tumor susceptible to bone disease. METHODS: The authors review the pathophysiology of these factors and their impact upon bone integrity. RESULTS: Steps that can be taken to minimize or eliminate bone morbidity including measurement of bone mineral density at treatment onset, adequate calcium intake, vitamins D and K supplementation, adequate sunlight exposure, weight-bearing exercises, fall prevention, avoidance of antiepileptic drugs linked to osteopenia, and judicious use and choice of glucocorticoids and anticoagulants are suggested. CONCLUSIONS: Medical management of osteoporosis related to brain tumor treatment with bisphosphonates, teriparitide, and calcitonin is beneficial, as is kyphoplasty for symptomatic vertebral compression fractures.