RESUMO
INTRODUCTION: Vitamin B12 deficiency is often associated with neurological disorders of which combined sclerosis of the spinal cord is a common manifestation. CASE REPORT: We report the case of a woman who presented cerebellar ataxia and cognitive deficits associated with leukoencephalopathy on the brain MRI. These symptoms were associated with vitamin B12 deficiency due to Biermer's disease. Vitamin B12 supplementation led to symptom improvement. Later her treatment was discontinued and the patient's clinical status worsened to a bedridden status. CONCLUSION: Ataxia cerebellar dementia and leukoencephalopathy can result from vitamin B12 deficiency. To limit the risks of sequelae, vitamin B12 supplementation should be started at an early stage.
Assuntos
Ataxia Cerebelar/patologia , Transtornos Cognitivos/patologia , Leucoencefalopatias/patologia , Deficiência de Vitamina B 12/complicações , Ataxia Cerebelar/etiologia , Ventrículos Cerebrais/patologia , Transtornos Cognitivos/etiologia , Feminino , Humanos , Imageamento por Ressonância Magnética , Pessoa de Meia-IdadeRESUMO
Hemimegalencephaly is a rare cerebral malformation that usually presents with mental retardation, controlateral hemiparesis and intractable seizures. We report a case of hemimegalencephaly diagnosed in adulthood based on MRI findings. The electroencephalogram initially suggested partial status epilepticus. The diagnosis of this cerebral malformation has been made easier thanks to recent progress in cerebral imagery with MRI. We describe and discuss the relevant encephalographic aspects.
Assuntos
Encéfalo/anormalidades , Eletroencefalografia , Adulto , Encéfalo/patologia , Epilepsia/diagnóstico , Humanos , Imageamento por Ressonância Magnética , MasculinoRESUMO
Reflex epileptic seizures of opercular origin have been described previously based on video-electroencephalographic monitoring, but very few patients have been explored with depth electrodes. We report a woman with late-onset epilepsy who had intractable seizures despite trials of several antiepileptic drugs. At the time of the depth-electrode recordings, seizures were usually continuous and occurred either spontaneously or were induced by movements of the jaw and mouth. The seizures originated in the deep central opercular cortex; localization was confirmed by a good surgical outcome.
Assuntos
Córtex Cerebral/fisiopatologia , Eletrodos Implantados , Eletroencefalografia/estatística & dados numéricos , Epilepsia Parcial Complexa/diagnóstico , Córtex Cerebral/cirurgia , Ingestão de Alimentos/fisiologia , Eletroencefalografia/métodos , Epilepsia Parcial Complexa/fisiopatologia , Epilepsia Parcial Complexa/cirurgia , Feminino , Seguimentos , Lobo Frontal/fisiopatologia , Lobo Frontal/cirurgia , Humanos , Arcada Osseodentária/fisiologia , Imageamento por Ressonância Magnética , Mastigação/fisiologia , Pessoa de Meia-Idade , Boca/fisiologia , Lobo Parietal/fisiopatologia , Lobo Parietal/cirurgia , Técnicas Estereotáxicas , Resultado do TratamentoRESUMO
Modifications of attention in cardiovascular field with the aim of a perceptive activity focused on a vegetative feature may include in man: a specific arousal component linked to significant visual information (blood pressure); an unspecific attention component (P300), obvious in modifications of averaged visual response in the same time to a background unsignificant stimulation.