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1.
Front Chem ; 12: 1361980, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38629105

RESUMO

Background and objectives: As microbes are developing resistance to antibiotics, natural, botanical drugs or traditional herbal medicine are presently being studied with an eye of great curiosity and hope. Hence, complementary and alternative treatments for uncomplicated pelvic inflammatory disease (uPID) are explored for their efficacy. Therefore, this study determined the therapeutic efficacy and safety of Sesamum indicum Linn seeds with Rosa damascena Mill Oil in uPID with standard control. Additionally, we analyzed the data with machine learning. Materials and methods: We included 60 participants in a double-blind, double-dummy, randomized standard-controlled study. Participants in the Sesame and Rose oil group (SR group) (n = 30) received 14 days course of black sesame powder (5 gm) mixed with rose oil (10 mL) per vaginum at bedtime once daily plus placebo capsules orally. The standard group (SC), received doxycycline 100 mg twice and metronidazole 400 mg thrice orally plus placebo per vaginum for the same duration. The primary outcome was a clinical cure at post-intervention for visual analogue scale (VAS) for lower abdominal pain (LAP), and McCormack pain scale (McPS) for abdominal-pelvic tenderness. The secondary outcome included white blood cells (WBC) cells in the vaginal wet mount test, safety profile, and health-related quality of life assessed by SF-12. In addition, we used AdaBoost (AB), Naïve Bayes (NB), and Decision Tree (DT) classifiers in this study to analyze the experimental data. Results: The clinical cure for LAP and McPS in the SR vs SC group was 82.85% vs 81.48% and 83.85% vs 81.60% on Day 15 respectively. On Day 15, pus cells less than 10 in the SR vs SC group were 86.6% vs 76.6% respectively. No adverse effects were reported in both groups. The improvement in total SF-12 score on Day 30 for the SR vs SC group was 82.79% vs 80.04% respectively. In addition, our Naive Bayes classifier based on the leave-one-out model achieved the maximum accuracy (68.30%) for the classification of both groups of uPID. Conclusion: We concluded that the SR group is cost-effective, safer, and efficacious for curing uPID. Proposed alternative treatment (test drug) could be a substitute of standard drug used for Female genital tract infections.

2.
Digit Health ; 9: 20552076231203604, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37799499

RESUMO

Objective: This study aims to develop a lightweight convolutional neural network-based edge federated learning architecture for COVID-19 detection using X-ray images, aiming to minimize computational cost, latency, and bandwidth requirements while preserving patient privacy. Method: The proposed method uses an edge federated learning architecture to optimize task allocation and execution. Unlike in traditional edge networks where requests from fixed nodes are handled by nearby edge devices or remote clouds, the proposed model uses an intelligent broker within the federation to assess member edge cloudlets' parameters, such as resources and hop count, to make optimal decisions for task offloading. This approach enhances performance and privacy by placing tasks in closer proximity to the user. DenseNet is used for model training, with a depth of 60 and 357,482 parameters. This resource-aware distributed approach optimizes computing resource utilization within the edge-federated learning architecture. Results: The experimental results demonstrate significant improvements in various performance metrics. The proposed method reduces training time by 53.1%, optimizes CPU and memory utilization by 17.5% and 33.6%, and maintains accurate COVID-19 detection capabilities without compromising the F1 score, demonstrating the efficiency and effectiveness of the lightweight convolutional neural network-based edge federated learning architecture. Conclusion: Existing studies predominantly concentrate on either privacy and accuracy or load balancing and energy optimization, with limited emphasis on training time. The proposed approach offers a comprehensive performance-centric solution that simultaneously addresses privacy, load balancing, and energy optimization while reducing training time, providing a more holistic and balanced solution for optimal system performance.

3.
Bioengineering (Basel) ; 9(12)2022 Dec 12.
Artigo em Inglês | MEDLINE | ID: mdl-36550999

RESUMO

The prevalence of anxiety among university students is increasing, resulting in the negative impact on their academic and social (behavioral and emotional) development. In order for students to have competitive academic performance, the cognitive function should be strengthened by detecting and handling anxiety. Over a period of 6 weeks, this study examined how to detect anxiety and how Mano Shakti Yoga (MSY) helps reduce anxiety. Relying on cardiac signals, this study follows an integrated detection-estimation-reduction framework for anxiety using the Intelligent Internet of Medical Things (IIoMT) and MSY. IIoMT is the integration of Internet of Medical Things (wearable smart belt) and machine learning algorithms (Decision Tree (DT), Random Forest (RF), and AdaBoost (AB)). Sixty-six eligible students were selected as experiencing anxiety detected based on the results of self-rating anxiety scale (SAS) questionnaire and a smart belt. Then, the students were divided randomly into two groups: experimental and control. The experimental group followed an MSY intervention for one hour twice a week, while the control group followed their own daily routine. Machine learning algorithms are used to analyze the data obtained from the smart belt. MSY is an alternative improvement for the immune system that helps reduce anxiety. All the results illustrate that the experimental group reduced anxiety with a significant (p < 0.05) difference in group × time interaction compared to the control group. The intelligent techniques achieved maximum accuracy of 80% on using RF algorithm. Thus, students can practice MSY and concentrate on their objectives by improving their intelligence, attention, and memory.

4.
Pharmaceuticals (Basel) ; 15(11)2022 Nov 08.
Artigo em Inglês | MEDLINE | ID: mdl-36355543

RESUMO

Herbal medicine and nutritional supplements are suggested to treat premenstrual somatic and psycho-behavioural symptoms in clinical guidelines; nonetheless, this is at present based on poor-quality trial evidence. Hence, we aimed to design a systematic review and meta-analysis for their effectiveness in alleviating premenstrual symptoms. The published randomized controlled trials (RCTs) were extracted from Google scholar, PubMed, Scopus and PROSPERO databases. The risk of bias in randomized trials was assessed by Cochrane risk-of-bias tool. The main outcome parameters were analysed separately based on the Premenstrual Symptom Screening Tool and PMTS and DRSP scores. Secondary parameters of somatic, psychological, and behavioural subscale symptoms of PSST were also analysed. Data synthesis was performed assuming a random-effects model, and standardized mean difference (SMDs) was analysed using SPSS version 28.0.0 (IBM, Armonk, NY, USA). A total of 754 articles were screened, and 15 RCTs were included (n = 1211 patients). Primary results for participants randomized to an intervention reported reduced PSST (n = 9), PMTS (n = 2), and DSR (n = 4) scores with (SMD = -1.44; 95% CI: -1.72 to -1.17), (SMD = -1.69; 95% CI: -3.80 to 0.42) and (SMD = 2.86; 95% CI: 1.02 to 4.69) verses comparator with substantial heterogeneity. Physical (SMD = -1.61; 95% CI = -2.56 to -0.66), behavioural (SMD = -0.60; 95% CI = -1.55 to0.35) and mood (SMD = 0.57; 95% CI = -0.96 to 2.11) subscale symptom groupings of PSST displayed similar findings. Fifty-three studies (n = 8) were considered at low risk of bias with high quality. Mild adverse events were reported by four RCTs. Based on the existing evidence, herbal medicine and nutritional supplements may be effective and safe for PMS.

5.
Artigo em Inglês | MEDLINE | ID: mdl-34199227

RESUMO

The use of artificial intelligence in health care has grown quickly. In this sense, we present our work related to the application of Natural Language Processing techniques, as a tool to analyze the sentiment perception of users who answered two questions from the CSQ-8 questionnaires with raw Spanish free-text. Their responses are related to mindfulness, which is a novel technique used to control stress and anxiety caused by different factors in daily life. As such, we proposed an online course where this method was applied in order to improve the quality of life of health care professionals in COVID 19 pandemic times. We also carried out an evaluation of the satisfaction level of the participants involved, with a view to establishing strategies to improve future experiences. To automatically perform this task, we used Natural Language Processing (NLP) models such as swivel embedding, neural networks, and transfer learning, so as to classify the inputs into the following three categories: negative, neutral, and positive. Due to the limited amount of data available-86 registers for the first and 68 for the second-transfer learning techniques were required. The length of the text had no limit from the user's standpoint, and our approach attained a maximum accuracy of 93.02% and 90.53%, respectively, based on ground truth labeled by three experts. Finally, we proposed a complementary analysis, using computer graphic text representation based on word frequency, to help researchers identify relevant information about the opinions with an objective approach to sentiment. The main conclusion drawn from this work is that the application of NLP techniques in small amounts of data using transfer learning is able to obtain enough accuracy in sentiment analysis and text classification stages.


Assuntos
COVID-19 , Atenção Plena , Inteligência Artificial , Humanos , Qualidade de Vida , SARS-CoV-2 , Inquéritos e Questionários
6.
J Biomed Inform ; 56: 265-72, 2015 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-26071682

RESUMO

Health telematics is a growing up issue that is becoming a major improvement on patient lives, especially in elderly, disabled, and chronically ill. In recent years, information and communication technologies improvements, along with mobile Internet, offering anywhere and anytime connectivity, play a key role on modern healthcare solutions. In this context, mobile health (m-Health) delivers healthcare services, overcoming geographical, temporal, and even organizational barriers. M-Health solutions address emerging problems on health services, including, the increasing number of chronic diseases related to lifestyle, high costs of existing national health services, the need to empower patients and families to self-care and handle their own healthcare, and the need to provide direct access to health services, regardless of time and place. Then, this paper presents a comprehensive review of the state of the art on m-Health services and applications. It surveys the most significant research work and presents a deep analysis of the top and novel m-Health services and applications proposed by industry. A discussion considering the European Union and United States approaches addressing the m-Health paradigm and directives already published is also considered. Open and challenging issues on emerging m-Health solutions are proposed for further works.


Assuntos
Doença Crônica/terapia , Acessibilidade aos Serviços de Saúde , Telemedicina/métodos , Telemedicina/tendências , Acesso à Informação , Idoso , Telefone Celular , Coleta de Dados , Atenção à Saúde , Pessoas com Deficiência , Registros Eletrônicos de Saúde , União Europeia , Humanos , Internet , Participação do Paciente , Relações Médico-Paciente , Autocuidado , Estados Unidos
7.
Health Informatics J ; 19(4): 300-11, 2013 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-24255053

RESUMO

Pressure ulcers frequently occur in patients with limited mobility, for example, people with advanced age and patients wearing casts or prostheses. Mobile information communication technologies can help implement ulcer care protocols and the monitoring of patients with high risk, thus preventing or improving these conditions. This article presents a mobile pressure ulcer monitoring platform (mULCER), which helps control a patient's ulcer status during all stages of treatment. Beside its stand-alone version, it can be integrated with electronic health record systems as mULCER synchronizes ulcer data with any electronic health record system using HL7 standards. It serves as a tool to integrate nursing care among hospital departments and institutions. mULCER was experimented with in different mobile devices such as LG Optimus One P500, Samsung Galaxy Tab, HTC Magic, Samsung Galaxy S, and Samsung Galaxy i5700, taking into account the user's experience of different screen sizes and processing characteristics.


Assuntos
Registros Eletrônicos de Saúde/estatística & dados numéricos , Internet , Úlcera por Pressão/terapia , Design de Software , Telemedicina/métodos , Prestação Integrada de Cuidados de Saúde , Feminino , Humanos , Masculino , Monitorização Fisiológica/instrumentação , Monitorização Fisiológica/métodos , Satisfação do Paciente/estatística & dados numéricos , Portugal , Úlcera por Pressão/fisiopatologia , Qualidade da Assistência à Saúde , Telemedicina/instrumentação , Cicatrização/fisiologia
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