Evaluation of the influence of ozonotherapy on the clinical parameters and MMP levels in patients with chronic and aggressive periodontitis.

PURPOSE: A comparison of the clinical status and salivary MMP levels after SRP alone or with ozonotherapy in patients with aggressive and chronic periodontitis. MATERIAL/METHODS: The study was performed in 52 generally healthy subjects with chronic or aggressive periodontitis. Group CP-S consisted of 12 patients with chronic periodontitis, who underwent scaling and root planing (SRP). In group CP-O there were 25 patients with chronic periodontitis who additionaly to SRP underwent ozonotherapy. The same therapy was performed in group AP, containing 15 patients with aggressive periodontitis. Plaque index, approximal plaque index, bleeding on probing, sulcus bleeding index, probing pocket depth and clinical attachment loss were measured at baseline, at two weeks and two months post-therapy. The levels of MMP-1, MMP-8 and MMP-9 were estimated in non-stimulated saliva with an ELISA method. RESULTS: All the clinical parameters assessed in the study groups were reduced after treatment. SRP with additional ozonotherapy provided an increase in MMP levels in patients with chronic periodontitis and a reduction in MMP levels in patients with aggressive periodontitis. CONCLUSIONS: SRP followed by ozonotherapy does not lead to further improvement in clinical periodontal parameters in patients with AP and CP.

Short time effect of elmex and Listerine mouthrinses on plaque in 12-year-old children.

PURPOSE: This study was conducted to determine the effect of two mouthrinses elmex and Listerine on plaque accumulation in 12-year-olds. MATERIAL AND METHODS: 30 12-year-old children took part in the clinical study. They were divided into three groups. Group I (10 people) was given Listerine to home use. Group II (10 people) was given elmex to home use. Group III (10 people) did not receive any mouthrinses. Following indices were used in first and base study Plaque Index (PI), Approximal Plaque Index (API) and Sulcus Bleeding Index (SBI). The statistical analysis was performed using T test for related samples and Spearman rank order correlations. RESULTS: Mean PI lessened in group I (Listerine) from 0.996 to 0.804 and group II (elmex) from 0.807 to 0.698. In group III it stayed almost at the same level. In all children values of API and SBI decreased after two weeks. Reduce of API in participants using Listerine was important statistically and it lessened from 57.4% to 48.1% (reduction by 16.2%). The other results of API and SBI were not statistically important. API in children using elmex lowered by 15.5%. Bleeding (SBI) in Listerine group decreased by 21.5% and in elmex group decreased by 24.5%. In control group diminish of SBI was only by 14.4%. CONCLUSIONS: In summary, this study has demonstrated that additional rinsing helped in reducing plaque and gingivitis in 12-year-olds but it is not as essential as motivation to everyday oral hygiene.