1.
J Asian Nat Prod Res
; 20(8): 709-718, 2018 Aug.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28971690
RESUMO
A new ceramide urticamide (1), two new secolignans urticalactones I (2) and â ¡ (3), and a new flavonoid glycoside urticaside (4), together with 15 known compounds (4-19), were isolated from the leaves of Urtica fissa, a folk medicine for rheumatism arthritis in China. The active evaluation results showed that 1, 2, 3, 8, and 13 possessed the potent anti-inflammatory. They could inhibit the release of NO and TNF-α in lipopolysaccharide (LPS) stimulated RAW 264.7 cells, with IC50 values less than 4.0 µM.