Biosynthesis of nano bimetallic Ag/Pt alloy from Crocus sativus L. extract: Biological efficacy and catalytic activity.

In this project, silver­platinum (AgPt) nanoparticles were prepared by using the Crocus sativus L. plant ethanolic extract. The AgPt nanoparticles were characterized by applying the various method as ultraviolet-visible and infrared spectroscopy, electron microscopy, and X-ray diffraction analysis. The morphology structural indicated that the AgPt nanoparticles were spherical particles with diameter about 36.0 nm. The FTIR spectroscopy shows the efficient stabilization of the AgPt nanoparticles by phytoconstituents. The Ag and AgPt nanoparticles have polyphenolic content, lower than the flavonoids and proanthocyanins contents. The AgPt nanoparticles depicted the highest antioxidant properties compared to the Ag nanoparticles and ascorbic acid. The results showed that the AgPt nanoparticles had a high antioxidant properties. In addition, the AgPt nanoparticles demonstrated the substantial antimicrobial and cytotoxic activities against pathogenic microbes and MCF-7 breast cancer cell line. The environmental chemistry analysis depicts that methyl orange can be degraded from water by catalytic degradation process with sodium borohydride. The AgPt nanoparticles were prosperous in catalytic degrading methyl orange following a first order kinetic model.

The effect of mutual task sharing on the number of needed health workers at the Iranian Health Posts; Does task sharing increase efficiency?

BACKGROUND: Nowadays task sharing is a way to optimize utilization of human resources for health. This study was designed to assess the effect of task sharing, mutually between midwives and Family Health Workforces (FHWs), on the number of needed staff across the Iranian Health Posts. METHODS: The workload and required number of midwives and FHWs in a Health Post were calculated and compared in two different scenarios of task division using a combined approach for estimating the number of required staff. In the first scenario, the midwives and FHWs provide their specialized services and in the second one, using mutual task sharing, a midwife provides all services traditionally delivered by FHWs and each FHW provides prenatal care in addition to the special tasks. Sensitivity analysis was performed to estimate the effects of different hypotheses. RESULTS: By applying mutual task sharing, the required number of staff for Health Posts was one midwife and two FHWs for a standard population of 12,500; one FHW less than that when no task sharing was applied. Sensitivity analysis illustrated that the number of needed staff is the same in both scenarios when different demographic, epidemiologic, cultural and organizational conditions were applied. CONCLUSION: Task sharing can reduce the required number of health workers which increases efficiency and productivity at health facilities. However, apart from a need to consider quality, acceptability, and feasibility of care, increasing efficiency must be judged against the contextual circumstances.

Proposing a framework for Health Impact Assessment in Iran.

BACKGROUND: Health impact assessments (HIA) of policies and projects are conducted differently in different contexts although there has been less HIA research to date in non-western countries. Global HIA research has however suggested that the technical conduct of HIAs is tied to broader conditions and influences to do with decision making and policy development. This study was conducted to develop a conceptual framework for progressing HIA in Iran including all factors influencing HIA planning and practice. METHODS: A comprehensive review of the international HIA literature identified core characteristics and principles. Then key informant interviews (n = 14) identified Iranian perspectives about factors influencing HIAs practice. These two stages resulted in a conceptual framework for HIA planning and practice including influencing factors and HIA content that was confirmed by our participants using e-Delphi technique. RESULTS: 91 HIA characteristics were organized into 20 categories. The interviews showed that four core concepts i.e. context, actors, HIA principles and policies and HIA capacities influence HIA practice in Iran. Comprehensive content of HIA considering all health dimensions and health determinants, assessing health inequalities, appropriate HIA type, quantification and participation is formed under influence of the above mentioned four factors. The study also demonstrated need to redefine the HIA principles and make decision about integration of HIA in Environmental Impact Assessment and also about the level of HIA before implementing HIA. The e-Delphi resulted in expert consensus on the variables, concepts, and their relations in proposed framework. CONCLUSIONS: Progressing HIA practice in Iran is perceived locally as subject to similar contextual conditions to those identified in the international literature. Further we have demonstrated the utility of mixed methods to progress HIA implementation in differing country contexts.