1.
Eksp Klin Farmakol
; 68(2): 47-50, 2005.
Artigo
em Russo
| MEDLINE
| ID: mdl-15934368
RESUMO
The results of experiments on white rats with CCl4-induced hepatitis showed that the combined introduction of cyclophosphamide and hepatoprotectors of the plant origin (lochein, maksar, silimarin) leads to a decrease in acute toxicity and to less pronounced manifestations of hepatotoxicity of cyclophosphamide. Hepatoprotectors decrease the activity of aminotransferases, reduce the level of bilirubin, normalize the content of protein andpipids in the blood serum, and suppress the development of morphological disorders in the liver.