RESUMO
The authors studied influence of occupational environment and work process factors on health of workers engaged into oil extraction. Analysis covered 7487 oil industry workers. Locomotory system and peripheral nervous system diseases, arterial hypertension, ENT diseases, gastro-intestinal disorders appeared to play leading role in the morbidity structure revealed. The studies helped to specify measures to preserve the oil workers health.
Assuntos
Indústrias Extrativas e de Processamento , Doenças Profissionais/epidemiologia , Exposição Ocupacional/efeitos adversos , Petróleo , Adulto , Bashkiria/epidemiologia , Doença Crônica , Gastroenteropatias/epidemiologia , Humanos , Hipertensão/epidemiologia , Masculino , Pessoa de Meia-Idade , Doenças Musculoesqueléticas/epidemiologia , Doenças Profissionais/induzido quimicamente , Doenças Profissionais/prevenção & controle , Ocupações , Otorrinolaringopatias/epidemiologia , Doenças do Sistema Nervoso Periférico/epidemiologia , Fatores de Risco , Fatores de TempoAssuntos
Nível de Saúde , Petróleo/história , Bashkiria , História do Século XX , História do Século XXI , HumanosRESUMO
Increasing use of aromatic hydrocarbons and their derivatives, known mutagens and carcinogens, in petrochemistry leads to higher number of workers having occupational contact with those chemicals. Most alien chemicals (xenobiotics) incorporated into human body do not demonstrate direct biological effects but undergo various biologic transformations. Humans proved to have genetic control over metabolism of xenobiotics entering the body, so various individuals depending on genetic features could be resistant or otherwise be extremely sensitive to chemical agents.
Assuntos
Poluentes Ocupacionais do Ar/farmacocinética , Citocromo P-450 CYP1A1/genética , Indústrias Extrativas e de Processamento , Glutationa Transferase/genética , Polimorfismo Genético , Xenobióticos/farmacocinética , Adulto , Idoso , Alelos , DNA/análise , Feminino , Deleção de Genes , Frequência do Gene/genética , Humanos , Inativação Metabólica/genética , Masculino , Pessoa de Meia-Idade , Petróleo , Reação em Cadeia da Polimerase , Federação Russa , Local de Trabalho/normasRESUMO
Thorough medical examination covered 1,400 individuals who work with oil and gas extraction devices, are aged 20 to 58 and have length of service 5 to 30 years. Findings are high prevalence of locomotory disorders, cardiovascular and gastrointestinal diseases, signs of ear exposure to noise. The authors justified complex of primary prophylactic measures including work optimization, meticulous occupational selection, qualified medical control and sanative measures.