RESUMO
Experimental investigations carried out in 154 white rats and 24 mongrel dogs have proved pathogenetical effectiveness and safety of using the method of parietal-cavitary sanitation of the intestine in treatment of acute experimental peritonitis. This method used in complex treatment in 28 patients with acute diffuse peritonitis allowed a 1.5-2 times quicker arrest of the syndrome of endogenous intoxication and liquidation of intestinal paresis. Infectious complications were 43% less frequent and the lethality indices were reduced by 9.5% as compared with the results obtained in the control group.
Assuntos
Ozônio/uso terapêutico , Peritonite/terapia , Irrigação Terapêutica/métodos , Doença Aguda , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Animais , Cães , Humanos , Pessoa de Meia-Idade , Lavagem Peritoneal/métodos , Ratos , Resultado do TratamentoRESUMO
Results of treatment of 214 patients with severe sepsis and septic shock were analyzed. 125 patients treated with various methods of ozonotherapy and hydropressive sanation of infectious foci formed the study group. Control group consisted of 89 patients treated according to generally accepted principles. Comparative analysis of treatment efficacy was carried out with numerous laboratory and instrumental study methods. It is shown that ozonotherapy and hydropressive technologies reduced a lethality from 39.2% in the control group to 25.6% in the study group.
Assuntos
Cuidados Críticos , Hidroterapia/métodos , Ozônio/uso terapêutico , Sepse/terapia , APACHE , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Terapia Combinada , Interpretação Estatística de Dados , Endoscopia , Humanos , Pessoa de Meia-Idade , Pressão , Sepse/diagnóstico , Sepse/mortalidade , Choque Séptico/diagnóstico , Choque Séptico/mortalidade , Choque Séptico/terapia , Fatores de Tempo , Resultado do TratamentoRESUMO
In the experiment on 144 mongrel dogs and 546 white rats the methods of ozone therapy and hydropressive treatment of the abdominal cavity have been worked out. These methods were used in the treatment of 94 patients aged from 13 to 89 years with severe forms of acute peritonitis. The control group consisted of 174 patients with peritonitis. A high antimicrobial effect was detected in the treatment of the abdominal cavity with microdisperse stream of the ozonated solution under pressure. After 1-2 procedures of the intestinal ozone dialysis the number of microbial bodies in the lumen of the small bowel in 65% of patients has decreased 2-3 times, the terms of elimination of the paresis has decreased 3-4 times, and more rapid dynamics of elimination of the endogenous intoxication syndrome was detected. The application of the developed programme of curative measures promote lowering of the lethality from 62.07% in the control group to 37.23%--in the test one.
Assuntos
Oxidantes Fotoquímicos/uso terapêutico , Ozônio/uso terapêutico , Peritonite/tratamento farmacológico , Desintoxicação por Sorção/métodos , Doença Aguda , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Animais , Cães , Sistemas de Liberação de Medicamentos , Seguimentos , Humanos , Intestino Delgado , Microesferas , Pessoa de Meia-Idade , Pressão , Ratos , Irrigação Terapêutica , Resultado do TratamentoRESUMO
The use of the method of jet dissection of tissue with the "jet scalpel" in resection of the liver for separation of the parenchyma allows to substantially decrease the intraoperative blood loss, to visualize the vessels and ducts and thus facilitates their ligation which prevents different complications. The device developed by the authors for reinfusion of blood is very helpful for preventing complications associated with the hemotransfusion therapy.