Clinical assessment of tolerability, immunological and cutaneous reactivity effects of an abbreviated schedule with Olea europaeanative extract of subcutaneous immunotherapy.

Summary: Objectives. To evaluate the tolerability and efficacy of Olea europaea subcutaneous immunotherapy (SCIT) on patients with rhinoconjunctivitis. Methods. In this open clinical trial patients were assigned to an abbreviated build-up scheme. The outcomes were: number, percentage, and severity of adverse reactions. Secondary outcomes included: changes in immunoglobulin titers and changes in dose-response skin prick tests. Results. Only 8 systemic reactions were registered, which represented 7/47 (14.9%) of patients and 8/429 (1.9%) of administered doses. Regarding immunological parameters the significant increases of sIgG and sIgG4 evidenced the changes in the patient immune system. Cutaneous reactivity decreased significantly. Conclusions. Olea europaea SCIT (Allergovac® depot ROXALL Medicina España S.A.) showed a good safety and tolerability profile. Immunological changes with induction of blocking IgG and decreases in cutaneous reactivity were detected in the patients.

Las matronas y la detección de la violencia en el embarazo / Midwives and intimate partner violence during pregnancy

La violencia de género es un grave problema social en todo el mundo, por su gravedad y su elevada prevalencia. Puede provocar patologías, incapacidad e incluso la muerte, y tiene repercusiones sobre la salud física, psíquica, social y sexual-reproductiva de la mujer. Si la violencia se ejerce durante el embarazo, puede tener consecuencias no sólo para la mujer, sino también para el feto en desarrollo y el futuro hijo. Existen una serie de funciones mínimas que los profesionales deben desarrollar, como preguntar sobre violencia de género con regularidad, informar y remitir a las mujeres que la sufran a los recursos disponibles de la comunidad, registrar los casos y conocer la legislación vigente del país

Gender violence is a major social problem at global level due to its serious nature and prevalence. It can lead to pathologies, disabilities and even death, and has repercussions for women’s physical, mental, social and sexual/reproductive health. If it occurs during pregnancy it can have consequences not only for the woman but for the developing foetus and the future child. There are a series of minimum functions professionals can perform, such as asking regularly about gender violence, informing women who suffer it about and referring them to the resources available in the community, recording cases and being familiar with current legislation in the country