RESUMO
Nanotechnology is an emerging branch of science that involves the engineering of functional systems on the nanoscale (1-100 nm). Nanotechnology has been used in biomedical and therapeutic agents with the aim of providing novel treatment solutions where small molecule size may be beneficial for modulation of biologic function. Recent investigation in nanomedicine has become increasingly important to cutaneous pathophysiology, such as functional designs directed towards skin cancers and wound healing. This review outlines the application of nanoparticles relevant to dermatologic surgery.
Assuntos
Procedimentos Cirúrgicos Dermatológicos , Portadores de Fármacos/uso terapêutico , Nanopartículas/uso terapêutico , Quitosana/administração & dosagem , Quitosana/uso terapêutico , Dendrímeros/administração & dosagem , Dendrímeros/uso terapêutico , Avaliação Pré-Clínica de Medicamentos , Fulerenos/administração & dosagem , Fulerenos/uso terapêutico , Humanos , Lipossomos/administração & dosagem , Estudos Multicêntricos como Assunto , Óxido Nítrico/administração & dosagem , Óxido Nítrico/uso terapêutico , Fármacos Fotossensibilizantes/administração & dosagem , Fármacos Fotossensibilizantes/uso terapêutico , Ensaios Clínicos Controlados Aleatórios como Assunto , Neoplasias Cutâneas/tratamento farmacológico , Neoplasias Cutâneas/cirurgia , Adesivos Teciduais/administração & dosagem , Virossomos/administração & dosagem , Cicatrização/efeitos dos fármacosRESUMO
Skin appearance is affected by intrinsic factors (eg, aging) and extrinsic factors (eg, UV light). A myriad of treatments has been created to combat the phenotypic effects of these forces, including vitamins and supplements. This article reviews these therapies with a focus on carotenoids; vitamins C, E, and D; as well as collagen, ceramides, and mixed supplements.
Assuntos
Suplementos Nutricionais , Pele/patologia , Vitaminas/administração & dosagem , Humanos , Envelhecimento da Pele/patologiaRESUMO
Patterned hair loss is common and can negatively impact quality of life. Patients often seek nonsurgical treatment options as a first-line measure to avoid undue risks and expense associated with surgery. This article discusses these noninvasive treatment options, with a focus on minoxidil, finasteride, dutasteride, spironolactone, low-level laser therapy (LLLT), platelet-rich plasma (PRP), microneedling, and oral supplements.
Assuntos
Alopecia/terapia , Cabelo/crescimento & desenvolvimento , Humanos , Terapia com Luz de Baixa Intensidade/métodos , Agulhas , Plasma Rico em Plaquetas , Qualidade de VidaRESUMO
As interest in complementary and alternative medicine has grown, the relationship between diet and skin health has become an active area of research. Various supplements, plant derivatives, and antioxidants have gained attention as possible tools to prevent signs of aging and improve skin conditions. As such, knowledge of clinical trial data is important to counsel patients appropriately on risks and benefits of these complementary treatments and lifestyle modifications. Herein, we review the role of diet and supplements in preventing photoaging and treating common skin conditions.
Assuntos
Antioxidantes/uso terapêutico , Suplementos Nutricionais , Envelhecimento da Pele , Dermatopatias/dietoterapia , Dermatopatias/prevenção & controle , Vitaminas/uso terapêutico , Dieta , Humanos , Pele/efeitos dos fármacos , Pele/fisiopatologia , Dermatopatias/fisiopatologiaRESUMO
Atopic dermatitis affects up to 20% of children and continues to increase in prevalence. Effective disease control is aimed at decreasing symptoms and reducing the frequency of flares, which may be complicated by secondary bacterial infections. Although recent advances have produced a number of non-systemic treatment options, topical corticosteroids remain a fundamental component of treatment algorithms. J Drugs Dermatol. 2019;18(2 Suppl):s112-116.
Assuntos
Antibacterianos/administração & dosagem , Coinfecção/tratamento farmacológico , Dermatite Atópica/tratamento farmacológico , Desonida/administração & dosagem , Glucocorticoides/administração & dosagem , Administração Cutânea , Ensaios Clínicos como Assunto , Coinfecção/microbiologia , Procedimentos Clínicos/normas , Dermatite Atópica/complicações , Dermatologia/normas , Humanos , Resultado do TratamentoRESUMO
Local anesthetics play an important role in cosmetic dermatology. Techniques using topical and regional anesthesia provide numerous pain management options for laser and injection treatments. In this article, we review strategies to maximize patient comfort during cosmetic interventions.