RESUMO
Epizootiological, clinical, bacteriological and haematological studies were carried out to assess the effectiveness of the recently developed cephalosporin preparation Cefquinome in the treatment of the puerperal septicaemia and toxaemia syndrome. Cefquinome was administered at three different doses (1, 2 and 4 mg/kg BW) to 188 sows with feverish puerperal illness. Amoxicillin (7 mg/kg BW) was used as a control drug. In 41% of cases endometritis was a monoinfection whereas in 70% of mammary infections mixed infections were diagnosed. Results showed that for therapy of puerperal septicaemia and toxaemia Cefquinome at doses of 2 mg/kg BW and 4 mg/kg BW is clearly more effective than the control drug Amoxicillin and Cefquinome at its lowest dose of 1 mg/kg BW.
Assuntos
Cefalosporinas/uso terapêutico , Transtornos Puerperais/veterinária , Sepse/veterinária , Doenças dos Suínos/tratamento farmacológico , Toxemia/veterinária , Amoxicilina/uso terapêutico , Animais , Cefalosporinas/farmacologia , Endometrite/tratamento farmacológico , Endometrite/veterinária , Feminino , Testes de Sensibilidade Microbiana , Transtornos Puerperais/tratamento farmacológico , Transtornos Puerperais/microbiologia , Sepse/tratamento farmacológico , Suínos , Síndrome , Toxemia/tratamento farmacológicoRESUMO
In a feeding trial lasting for months Halothane-positive fattening pigs were put on a diet containing different concentrations of vitamin E and selenium. After a Myostress application vitamin E and selenium were additionally injected in order to examine stress resistance (CK-test) and regenerative capacity (histological examination of Musculus longissimus dorsi) of skeletal muscle. The study revealed that neither high dietary levels of vitamin E/selenium nor a vitamin E/selenium treatment applied after stress are capable of preventing stress related myopathy nor can they influence its healing up favourably.