RESUMO
The paper presents the results of clinical examination of 114 patients aged 60-88 years with acute odontogenous periostitis receiving treatment in in-patient maxillofacial surgery unit. The dynamic of clinical symptoms is used to carry out the comparative effectiveness study of several peroral antibiotics in elderly patients.
Assuntos
Antibacterianos/uso terapêutico , Doenças Maxilomandibulares/tratamento farmacológico , Doenças Maxilomandibulares/microbiologia , Periostite/tratamento farmacológico , Periostite/microbiologia , Doença Aguda , Idoso , Idoso de 80 Anos ou mais , Combinação Amoxicilina e Clavulanato de Potássio/uso terapêutico , Ciprofloxacina/análogos & derivados , Feminino , Fluoroquinolonas/uso terapêutico , Humanos , Doenças Maxilomandibulares/diagnóstico , Masculino , Pessoa de Meia-Idade , Ofloxacino/uso terapêutico , Periostite/diagnóstico , Supuração/diagnóstico , Supuração/tratamento farmacológico , Supuração/microbiologia , Resultado do TratamentoRESUMO
A comprehensive treatment with Likopid of chronic generalized parodontitis in 114 elderly and senile patients was carried out. The state of mechanisms of innate immunity (phagocytosis mechanisms) as well as the profile of proinflammatory cytokines was assessed. The effect of antibiotic-resistant strains of prior microflora on the combined therapy of patients of different age with chronic generalized parodontitis was studied. It is established that due to presence of various types of opportunistic pathogens in patients of different age with parodontitis using the prophylactic antibiotics for the empirical (to determine the antibiotic resistance), a combination of Metronidazole and Lincomycin with the mandatory appointment of immunomodulatory drugs for activation of monocyte-phagocytic system of the patient elderly is most advisable. Use of the drug , "Likopid" significantly improves the results of treatment the elderly and old patients with chronic generalized parodonthitis.
Assuntos
Acetilmuramil-Alanil-Isoglutamina/análogos & derivados , Antibacterianos/uso terapêutico , Antibioticoprofilaxia/métodos , Periodontite Crônica/tratamento farmacológico , Terapia Combinada/métodos , Periodonto/efeitos dos fármacos , Fagocitose/efeitos dos fármacos , Acetilmuramil-Alanil-Isoglutamina/uso terapêutico , Adulto , Idoso , Periodontite Crônica/imunologia , Periodontite Crônica/fisiopatologia , Citocinas/imunologia , Resistência Microbiana a Medicamentos , Feminino , Humanos , Fatores Imunológicos/uso terapêutico , Lincomicina/uso terapêutico , Masculino , Metronidazol/uso terapêutico , Testes de Sensibilidade Microbiana , Pessoa de Meia-Idade , Monitorização Imunológica , Periodonto/imunologia , Periodonto/microbiologia , Índice de Gravidade de Doença , Resultado do TratamentoRESUMO
In the above study, the comparison of efficiency of complex treatment of elderly and senile patients with fractures of mandibula has been carried out. After osteosynthesis of mandibula with mini-plates, frequency of development of traumatic osteomyelitis in these patients was lower than that after osteosynthesis by means of bone suture, especially in the group of patients who were admitted with signs of inflammation of osteal wound, where traumatic osteomyelitis developed 3 times less often than after osteosynthesis with bone suture. At bilateral fractures of mandibula, osteosynthesis with bone suture is not prescribed to the elderly patients who are admitted with signs of inflammation of osteal wound. Application of mini-plates for osteosynthesis at fractures of mandibula in the elderly patients enabled to restore mandibula motion and chewing function within much earlier terms.
Assuntos
Fixação Interna de Fraturas/métodos , Serviços de Saúde para Idosos/organização & administração , Fraturas Mandibulares/cirurgia , Idoso , Idoso de 80 Anos ou mais , Placas Ósseas , Feminino , Fixação Interna de Fraturas/instrumentação , Consolidação da Fratura/efeitos da radiação , Humanos , Terapia com Luz de Baixa Intensidade , Masculino , Fraturas Mandibulares/diagnóstico por imagem , Fraturas Mandibulares/radioterapia , Pessoa de Meia-Idade , Radiografia , Resultado do TratamentoRESUMO
Bioceramics-based materials manufactured in Russia were experimentally and clinically tried with the aim of optimizing repair osteogenesis of the jaws. Powder, granules, and porous blocks of hydroxyapatite alone and mixed with tricalcium phosphate may be effectively used for plastic repair of osseous pouches and post-operative defects of the jaws in surgical treatment of periodontitis, periradicular cysts of the jaws, and for filling the wells after removal of teeth.
Assuntos
Substitutos Ósseos/uso terapêutico , Cerâmica/uso terapêutico , Materiais Dentários/uso terapêutico , Adolescente , Adulto , Idoso , Animais , Avaliação Pré-Clínica de Medicamentos , Feminino , Humanos , Masculino , Mandíbula/efeitos dos fármacos , Pessoa de Meia-Idade , Osteogênese/efeitos dos fármacos , Doenças Periodontais/cirurgia , Coelhos , Fatores de TempoRESUMO
Experimental studies making use of morphological and x-ray methods demonstrated that in comparison with control (filling of mandibular bone defects with blood clots) chonsuride, an animal polysaccharide, promoted earlier filling of postoperative bone cavities with connective tissue replacement of this tissue with coarse-fiber bone tissue. Secondary restructuring and mineralization of bone regenerate were enhanced as well.
Assuntos
Regeneração Óssea/efeitos dos fármacos , Substitutos Ósseos/farmacologia , Sulfatos de Condroitina/farmacologia , Mandíbula/efeitos dos fármacos , Animais , Substitutos Ósseos/uso terapêutico , Sulfatos de Condroitina/uso terapêutico , Avaliação Pré-Clínica de Medicamentos , Feminino , Masculino , Mandíbula/diagnóstico por imagem , Mandíbula/patologia , Mandíbula/cirurgia , Coelhos , Radiografia , Fatores de Tempo , Cicatrização/efeitos dos fármacosRESUMO
Presents the immediate and late (a follow-up of up to 3 years) results of the treatment of 30 patients with oral mucosa paresthesia by the method of hirudotherapy. Discusses the factors influencing the treatment efficacy and leading to recurrences of the disease.
Assuntos
Sanguessugas , Doenças da Boca/terapia , Parestesia/terapia , Idoso , Animais , Doença Crônica , Feminino , Seguimentos , Humanos , Masculino , Métodos , Pessoa de Meia-Idade , Doenças da Boca/epidemiologia , Parestesia/epidemiologia , Recidiva , Indução de RemissãoRESUMO
Immediate and late (up to 4 years) results of acupuncture are described in 42 patients with oral mucosa paresthesias. The data suggest that this is an efficient technique.