RESUMO
The majority of patients with Covid-19 have a good outcome. However, complications principally of acute respiratory distress syndrome (ARDS) and multiple-organ failure can occur rapidly. Leptospirosis, a zoonotic disease, is similar to Covid-19 in that most infections are mild or asymptomatic and only a small number develop ARDS. Cytokine storm is considered to be the main incriminating factor in both. High dose steroids have been used to ameliorate the effects in leptospirosis, and similarly, reports suggest a benefit in Covid-19. SARS CoV-2 and leptospira, one a virus and the other a bacterium, are two species separated by millions of years of evolution, but producing illnesses with similar spectra, with cytokine storm being the common precipitating factor. As data are accrued from around the world, more light may be shed on features analogous to both pathways.
Assuntos
Tratamento Farmacológico da COVID-19 , Síndrome da Liberação de Citocina/tratamento farmacológico , Leptospirose/tratamento farmacológico , Esteroides/uso terapêutico , Animais , COVID-19/complicações , COVID-19/virologia , Síndrome da Liberação de Citocina/etiologia , Humanos , Leptospira/patogenicidade , Leptospirose/complicações , Leptospirose/microbiologia , Masculino , Síndrome do Desconforto Respiratório/tratamento farmacológico , Síndrome do Desconforto Respiratório/etiologia , SARS-CoV-2/patogenicidadeRESUMO
BACKGROUND: Eucalyptus oil poisoning is rare in adults but is not that uncommon in children. The common side effects in children include depression in the level of consciousness, ataxia, seizures, and vomiting. Unlike in children, seizures are unusual in adult patients with eucalyptus oil poisoning. We report the cases of two patients with eucalyptus oil poisoning, both adults who unintentionally took eucalyptus oil and presented to the emergency room of our institution with seizures. CASE PRESENTATION: Two adult Indian men who unintentionally consumed eucalyptus oil presented to the emergency room of our institution with seizures. In both patients, arterial blood gas analysis showed the presence of severe metabolic acidosis. Both the patients were managed in the intensive care unit and received standard supportive care. Metabolic acidosis was corrected with intravenous bicarbonate infusion. They were successfully discharged on the fourth day. CONCLUSIONS: All physicians should be aware of the toxic effects of eucalyptus oil, which is used often in daily life in India. Supportive care in an intensive care unit, including rapid correction of metabolic acidosis and adequate maintenance of hemodynamic parameters, will lead to a rapid recovery. Warning labels should be made mandatory on all products that contain eucalyptus oil.
Assuntos
Acidose/induzido quimicamente , Óleo de Eucalipto/intoxicação , Plantas Medicinais/intoxicação , Convulsões/induzido quimicamente , Bicarbonato de Sódio/administração & dosagem , Lesões Acidentais , Acidose/tratamento farmacológico , Adulto , Humanos , Infusões Intravenosas , Masculino , Convulsões/tratamento farmacológico , Resultado do Tratamento , Adulto JovemRESUMO
We report a case of a Russell's viper (Daboia russelii) bite involving a 55-year-old male who developed a bilateral thalamic infarction. Although the coagulopathy was controlled within twenty-four hours, the patient became restless and disoriented. Due to the initial prolonged clotting time, we suspected an intracranial bleed. T2 magnetic resonance imaging (MRI) of the brain showed bilateral infarcts of the thalamus. Cerebral infarction secondary to snake envenomation has been reported before, but to our knowledge bilateral involvement of the thalamus has not been reported.