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1.
Expert Rev Clin Pharmacol ; 16(5): 435-451, 2023 May.
Artigo em Inglês | MEDLINE | ID: mdl-37083548

RESUMO

INTRODUCTION: Extraction of impacted molar teeth is a common procedure performed by oral surgeons and general dentists, with postoperative pain being a significant adverse event post-surgery. If mismanaged, pain can lead to complications that impact oral and systemic health. The current scourge of the opioid epidemic has ushered in a new era of provider-directed analgesic (PDA) therapy in dentistry. AREAS COVERED: This article provides an in-depth review on the major pharmacological and therapeutic properties of established and alternative analgesics used to manage dental pain. EXPERT OPINION: Substantial evidence-based literature shows a combination of a non-steroidal anti-inflammatory drug (NSAID; e.g. ibuprofen) and acetaminophen provides superior pain relief than single-agent or combination opioid regimens. However, there are clinical scenarios (e.g. severe pain) where a short-course opioid prescription is appropriate in select patients, for which a 2-3-day treatment duration is typically sufficient. Alternative agents (e.g. caffeine, gabapentin, phytotherapies), typically in combination with established agents, can mitigate postoperative dental pain. Some evidence suggests preemptive therapies (e.g. corticosteroids, NSAIDs) reduce amounts of postsurgical analgesic consumption and might lessen opioid prescription burden. In summary, this comprehensive review provides an opportune update on the evolving landscape of pharmacotherapy for acute postsurgical dental pain, informing best practices for PDA in the dental setting.


Assuntos
Analgesia , Analgésicos Opioides , Humanos , Anti-Inflamatórios não Esteroides/efeitos adversos , Analgésicos , Dor Pós-Operatória/tratamento farmacológico , Dor Pós-Operatória/etiologia
2.
J Am Dent Assoc ; 134(7): 888-93, 2003 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-12892447

RESUMO

BACKGROUND: Dentists administer thousands of local anesthetic injections every day with few reports of serious complications. However, misjudging the anatomy involved during local anesthetic administration can result not only in inadequate or incomplete anesthesia, but in other complications such as paresthesia, bleeding or hematoma formation, or in serious systemic complications. OVERVIEW: The authors discuss anatomical considerations that dentists should keep in mind when administering local anesthetic injections. In particular, they discuss ways in which dentists can minimize the risk of nerve or vascular injury, as well as systemic complications. CONCLUSIONS AND CLINICAL IMPLICATIONS: Even the most experienced practitioner can benefit from a periodic review of the anatomy associated with local anesthesia. This article offers dentists the opportunity to consider needle placement with regard to location of nerves, blood vessels and glands, and to review injection protocols that can minimize the risk of complications.


Assuntos
Anestesia Dentária/efeitos adversos , Anestesia Local/efeitos adversos , Face/anatomia & histologia , Face/irrigação sanguínea , Face/inervação , Hemorragia/prevenção & controle , Humanos , Injeções/efeitos adversos , Parestesia/prevenção & controle , Fatores de Risco
3.
J Am Dent Assoc ; 134(6): 753-60, 2003 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-12839412

RESUMO

BACKGROUND: To achieve profound dental local anesthesia, it is necessary for the dentist to have a thorough knowledge of the details of sensory innervation to the maxilla and mandible. Since the early 1970s, dentistry has experienced a resurgence of interest in the neuroanatomical basis of local anesthesia, resulting in numerous scientific reports on the subject. OVERVIEW: Current studies afford a more detailed knowledge of the branching of various divisions of the trigeminal nerve, the great sensory nerve of the head region. In this article, the authors provide an update of the peripheral distribution of the trigeminal nerve to enhance induction of safe and effective dental local anesthesia. CONCLUSIONS AND PRACTICAL IMPLICATIONS: An understanding of the potential variations in innervation should help the dentist improve his or her ability to induce profound local anesthesia.


Assuntos
Anestesia Dentária/métodos , Anestesia Local/métodos , Mandíbula/inervação , Maxila/inervação , Bloqueio Nervoso/métodos , Nervo Trigêmeo/anatomia & histologia , Anestésicos Locais , Humanos , Dente/inervação
4.
J Am Dent Assoc ; 134(2): 228-34, 2003 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-12636129

RESUMO

BACKGROUND: The authors review four techniques for producing block and topical anesthesia that have been advocated as alternatives to conventional methods. The objective of this review is to examine the basis for each method's application in dentistry, including scientific studies where available. TYPES OF STUDIES REVIEWED: The authors reviewed both historical (1912 and 1923) and more recent (1977 to present) reports relating to specific local anesthetic delivery systems. While this article is not a comprehensive literature review, the clinical reports and double-blind scientific reports from peer-reviewed publications are specific to the various attributes of the delivery systems being described. In addition, the authors identify any claims lacking scientific validity. RESULTS: Several alternative local anesthetic delivery systems are clinically effective in producing local anesthesia. Potential adverse effects and complications do, however, differ from one technology to another, depending on the mechanical characteristics of the particular system. Finally, all of the alternative local anesthetic delivery systems represent additional costs when compared with those of conventional applications, and cost-effectiveness is an important factor to be considered when implementing these systems in a dental practice. CLINICAL IMPLICATIONS: Alternative local anesthetic delivery systems may offer some advantages over conventional techniques in certain situations, although the costs may outweigh the advantages in certain cases.


Assuntos
Anestesia Dentária , Anestésicos Locais/administração & dosagem , Administração Tópica , Anestesia Dentária/efeitos adversos , Anestesia Dentária/instrumentação , Anestesia Dentária/métodos , Anestesia Local/efeitos adversos , Anestesia Local/instrumentação , Anestesia Local/métodos , Animais , Frequência Cardíaca/efeitos dos fármacos , Humanos , Bombas de Infusão , Injeções/instrumentação , Arcada Osseodentária , Nervo Maxilar , Bloqueio Nervoso/efeitos adversos , Bloqueio Nervoso/instrumentação , Bloqueio Nervoso/métodos , Ligamento Periodontal
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