RESUMO
Androgenetic alopecia is the most common hair loss disorder, affecting both men and women. Initial signs of androgenetic alopecia usually develop during teenage years leading to progressive hair loss with a pattern distribution. Moreover, its frequency increases with age and affects up to 80% Caucasian men and 42% of women. Patients afflicted with androgenetic alopecia may undergo significant impairment of quality of life. The European Dermatology Forum (EDF) initiated a project to develop evidence-based guidelines for the treatment of androgenetic alopecia. Based on a systematic literature research the efficacy of the currently available therapeutic options was assessed and therapeutic recommendations were passed in a consensus conference. The purpose of the guideline is to provide dermatologists with an evidence-based tool for choosing an efficacious and safe therapy for patients with androgenetic alopecia.
Assuntos
Alopecia/terapia , Medicina Baseada em Evidências , Inibidores de 5-alfa Redutase/uso terapêutico , Quimioterapia Combinada , Dutasterida/uso terapêutico , Feminino , Finasterida/uso terapêutico , Cabelo/transplante , Humanos , Terapia com Luz de Baixa Intensidade , Masculino , Minoxidil/uso terapêutico , Avaliação de Resultados em Cuidados de Saúde , Plasma Rico em Plaquetas , Guias de Prática Clínica como Assunto , Vasodilatadores/uso terapêuticoRESUMO
BACKGROUND: Coronary artery disease is an important cause of death and disability among older women. Modification in lipid profile lowers the risk of coronary artery disease. It is claimed that yoga and transcendental meditation have a cholesterol lowering effect. This study was designed to assess the effect of raja yoga meditation of Brahmakumaris which is very simple to practice, on serum lipids in normal Indian women. METHODS AND RESULTS: 49 normal female volunteers were the subjects. They were divided into pre-menopausal (n=23) and post-menopausal (n=26) groups. They were further divided into non-meditators (who had never done any kind of meditation), short-term meditators (meditating for 6 months to 5 years) and long-term meditators (meditating for more than 5 years). Lipid profile was assessed using their respective reagent sets. Serum cholesterol, triglyceride and low-density lipoprotein-cholesterol in nonmeditators were significantly more in post-menopausal women as compared to pre-menopausal women. Serum cholesterol and low density lipoprotein-cholesterol were significantly lowered in both short and long term meditators as compared to non-meditators in post-menopausal women. No significant difference was observed in lipid profile in pre-menopausal women. CONCLUSION: Raja yoga meditation lowered serum cholesterol and low-density lipoprotein-cholesterol in post-menopausal women thus reducing the risk of coronary artery disease in them.