RESUMO
A 37-year-old man was admitted to our hospital with acute phenobarbital poisoning. On arrival, he was in deep coma with respiro-circulatory depressions. The serum concentration of the agent was elevated to 149.04 µg/mL which was consistent with a lethal concentration level. He underwent a gastric lavage, administration of activated charcoal, urinary alkalinazation and bowel irrigation. Respiro-circulatory status was recovered rapidly, while the serum concentration of phenobarbital did not decrease smoothly. Although the concentration of the agent decreased to 77.07 µg/mL that should be a comatose level, BIS values were gradually elevated, and then eventually the patient regained his consciousness. Because he was a chronic user of Vegetamin-A containing phenobarbital, the serum level might not have been correlated with symptoms. BIS values were highly reflective of the consciousness level, so it could be a useful indicator for predicting the consciousness levels of patients in deep coma with acute poisoning from hypnotic agents.
Assuntos
Clorpromazina/intoxicação , Coma/induzido quimicamente , Coma/diagnóstico , Monitores de Consciência , Hipnóticos e Sedativos/intoxicação , Fenobarbital/intoxicação , Recuperação de Função Fisiológica , Inconsciência/induzido quimicamente , Inconsciência/diagnóstico , Doença Aguda , Adulto , Carvão Vegetal/administração & dosagem , Clorpromazina/sangue , Coma/fisiopatologia , Coma/terapia , Combinação de Medicamentos , Enema , Lavagem Gástrica , Humanos , Hipnóticos e Sedativos/sangue , Masculino , Fenobarbital/sangue , Comprimidos , Resultado do Tratamento , Inconsciência/fisiopatologia , Inconsciência/terapiaRESUMO
Molasses-based distilleries generate large volumes of a highly polluted and dark brown-colored wastewater. The present work describes the way in which an adsorbent-column chromatography can effectively remove the colorant and produce biomass ethanol from sugarcane or sugar beet molasses. It was found that the color and chemical oxygen demand of the resulting wastewater was respectively reduced by approximately 87% and 28% as compared with conventional molasses fermentation. Gas chromatography showed that the decolorized molasses maintained good ethanol productivity almost equal to that of the original molasses. Furthermore, it was revealed that the colorant concentrations of about 5 mg ml(-1) in the medium were the most favorable for ethanolic fermentation. In summary, we have concluded that this method is the most effective when the adsorbent chromatography is performed just before molasses fermentation and that the decolorized molasses is an ideal substrate for fuel ethanol production.