RESUMO
Experimental and clinical data on the employment of assisted circulation with extracorporeal oxygenation of the blood, exchange replacement of the blood in high volumes, hemoperfusion, and hyperbaric therapy in the treatment of exotoxic shock caused by methemoglobin-forming and corrosive poisons demonstrate a high efficacy of assisted circulation in the normalization of central hemodynamics (which permits exchange replacement of the blood and hemoperfusion), of the hepatorenal function, hemostasis, and other parameters of the internal media in humans and animals. The method is recommended for wide use at large reanimation and toxicological centers.
Assuntos
Circulação Assistida , Transfusão Total , Exotoxinas , Oxigenação por Membrana Extracorpórea , Hemoperfusão , Oxigenoterapia Hiperbárica , Choque Séptico/terapia , Adulto , Animais , Cães , Feminino , Hemodinâmica , Hemostasia , Humanos , Rim/fisiopatologia , Fígado/fisiopatologia , Masculino , Choque Séptico/fisiopatologiaRESUMO
The study of 34 patients with septic shock has shown that active detoxication with hemosorption leads to prompt stabilization of systemic hemodynamics with a considerable increase in oxygen delivery and consumption. When hemosorption was followed by HBO procedures the functional capacities of the cardiac muscle were improved, the elimination of anaerobic metabolism inversion facilitated, and the level of oxygen consumption normalized.