[The role of oxidative metabolism in development of adaptation effect after exposure to ethanol and pulsed hypoxic training]. / Rol' okysnoho metabolizmu u formuvanni adaptatsiinoho efektu za umov vplyvu etanolu ta koryhuiuchoï diï impul'snoho hipoksychnoho trenuvannia.

The activities of lipid peroxidation and the antioxidative defence systems, the content of nitric oxide metabolites, an erythrocyte resistance to peroxide hemolysis in rats exposed to ethanol and hypoxic training were studied. We also evaluated the detoxicant capacity of the liver by 4-aminoantipyrine clearance. It was established that an effect of ethanol was accompanied by the disturbances in the oxygen-dependent metabolic reactions if the liver in different organs and systems. The results have confirmed the expediency of using the hypoxic training in the complex treatment of the chronic alcohol intoxication.

[Metabolic effect of amaranth oil and impulse hypoxic training under chronic fluoride intoxication and small doses of ionizing radiation]. / Metabolichni efekty oliï amarantu ta impul'snoho hipoksychnoho trenuvannia za umov diï ftorystoï intoksykatsiï ta malykh doz radiatsiï.

Lipid peroxidation and antioxidative defence system in blood, liver and heart tissues, nitric oxide metabolites content in brain tissue of rats under binary action of small-doses of ionizing radiation and fluoride intoxication treated by amaranth oil and interval hypoxic training have been studied. Complex using of amaranth oil and interval hypoxic training result in increase both enzymatic, as nonezymatic links of antioxidant defence in all investigated tissues. It was revealed also enhance of NO system metabolites content in brain gomogenate. In this conditions lipid peroxidation processes in liver and heart tissues normalize comparison with essential increase level LPO under binary action influence. On the basis of obtained results LPO metabolites content we can suppossed that complex using of amaranth oil and interval hypoxic training result in increase of organism adaptative possibility. This complex can be using for binary action of ionizing radiation and fluoride intoxication correction.