RESUMO
The present study was aimed to archive the etnhnomedicinal knowledge of plants used by inhabitants of seven villages of HolguiÌn, Eastern region, Cuba. The ethnomedicinal information was collected through interviews. The collected data were analyzed through use value (UV), informant consensus factor (Fic) and fidelity level (FL). A total of 195 species of plants distributed in 166 genera belonging to 70 families were identified for the treatment of 17 ailment categories. The most treated conditions were digestive and liver disorders. The most important species according to their use value were Lippia alba (Mill.) N.E. Br. ex Britton & P. Wilson (0.236) and Annona muricata L. (0.194). Cancer and tumors had the Fic value of 0.94. A total of 19 species has a highest FL of 100 percent. This was the first ethnobotanical survey conducted in HolguiÌn region, which will contribute to preserve valuable information of medicinal plants that may otherwise be lost to future generations.
El presente estudio tuvo como objetivo registrar el conocimiento etnomedicinal de las plantas usadas por los pobladores en 7 comunidades de HolguiÌn, RegioÌn Oriental, Cuba. La informacioÌn fue recogida a traveÌs de entrevistas y analizada cuantitativamente mediante indicadores etnobotaÌnicos: valor de uso (UV), factor del consenso de los informantes (Fic) e iÌndice de fidelidad (FL). Fueron reportadas un total de 195 especies de plantas, distribuidas en 166 geÌneros y 70 familias, para el tratamiento de 17 categoriÌas de usos. Las indicaciones maÌs frecuentes fueron los problemas digestivos y del hiÌgado. Las especies medicinales con mayor UV fueron Lippia alba (Mill.) N.E. Br. ex Britton & P. Wilson (0.236) y Annona muricata L. (0.194). CaÌncer y tumores tuvieron el valor maÌs alto de Fic (0.94). Solo 19 especies presentaron un valor de FL de 100 %. Este primer estudio contribuiraÌ a preservar la informacioÌn de las plantas medicinales y que esta no se pierda en las futuras generaciones.
Assuntos
Humanos , Plantas Medicinais , Etnobotânica , Inquéritos e Questionários , CubaRESUMO
Thyroid hormones (THs) act in the brain to modulate energy balance. We show that central triiodothyronine (T3) regulates de novo lipogenesis in liver and lipid oxidation in brown adipose tissue (BAT) through the parasympathetic (PSNS) and sympathetic nervous system (SNS), respectively. Central T3 promotes hepatic lipogenesis with parallel stimulation of the thermogenic program in BAT. The action of T3 depends on AMP-activated protein kinase (AMPK)-induced regulation of two signaling pathways in the ventromedial nucleus of the hypothalamus (VMH): decreased ceramide-induced endoplasmic reticulum (ER) stress, which promotes BAT thermogenesis, and increased c-Jun N-terminal kinase (JNK) activation, which controls hepatic lipid metabolism. Of note, ablation of AMPKα1 in steroidogenic factor 1 (SF1) neurons of the VMH fully recapitulated the effect of central T3, pointing to this population in mediating the effect of central THs on metabolism. Overall, these findings uncover the underlying pathways through which central T3 modulates peripheral metabolism.
Assuntos
Metabolismo Energético , Hipotálamo/metabolismo , Proteína Quinase 8 Ativada por Mitógeno/metabolismo , Transdução de Sinais , Hormônios Tireóideos/metabolismo , Tecido Adiposo Marrom/metabolismo , Animais , Metabolismo dos Lipídeos , Fígado/metabolismo , Masculino , Camundongos Endogâmicos C57BL , Ratos , Ratos Sprague-Dawley , Termogênese , Tri-Iodotironina/metabolismoRESUMO
Pedilanthus tithymaloides (L) Poit (ítamo real) se emplea tradicionalmente y en estomatología por la acción antiinflamatoria. Objetivos: evaluar la estabilidad de 2 tinturas de ítamo real almacenadas en condiciones de refrigeración y temperatura ambiente durante 1 año...(AU)
Pedilanthus tithymaloides (L) Point (ítamo real) is traditionally used in dentistry due to its antiinflammatory effect. Objectives: to evaluate the stability of two itamo real tinctures stored under refrigeration conditions and at room temperature for one year...(AU)
Assuntos
Plantas Medicinais/crescimento & desenvolvimento , Reatividade-EstabilidadeRESUMO
Pedilanthus tithymaloides (L) Poit (ítamo real) se emplea tradicionalmente y en estomatología por la acción antiinflamatoria. Objetivos: evaluar la estabilidad de 2 tinturas de ítamo real almacenadas en condiciones de refrigeración y temperatura ambiente durante 1 año...
Pedilanthus tithymaloides (L) Point (ítamo real) is traditionally used in dentistry due to its antiinflammatory effect. Objectives: to evaluate the stability of two itamo real tinctures stored under refrigeration conditions and at room temperature for one year...