[Exploration and example interpretation of real-world herbal prescription classification based on similarity matching algorithm].

In observational studies, herbal prescriptions are usually studied in the form of "similar prescriptions". At present, the classification of prescriptions is mainly based on clinical experience judgment, but there are some problems in manual judgment, such as lack of unified criteria, labor consumption, and difficulty in verification. In the construction of a database of integrated traditional Chinese and western medicine for the treatment of coronavirus disease 2019(COVID-19), our research group tried to classify real-world herbal prescriptions using a similarity matching algorithm. The main steps include 78 target prescriptions are determined in advance; four levels of importance labeling shall be carried out for the drugs of each target prescription; the combination, format conversion, and standardization of drug names of the prescriptions to be identified in the herbal medicine database; calculate the similarity between the prescriptions to be identified and each target prescription one by one; prescription discrimination is performed based on the preset criteria; remove the name of the prescriptions with "large prescriptions cover the small". Through the similarity matching algorithm, 87.49% of the real prescriptions in the herbal medicine database of this study can be identified, which preliminarily proves that this method can complete the classification of herbal prescriptions. However, this method does not consider the influence of herbal dosage on the results, and there is no recognized standard for the weight of drug importance and criteria, so there are some limitations, which need to be further explored and improved in future research.

[Exploration on the rules of acupoints selection for phlegm disorder treated with acupuncture and moxibustion based on ancient literature study].

OBJECTIVE: To analyze the rules of acupoints selection for phlegm disorder in treatment with acupuncture and moxibustion in ancient literature so as to provide guidance to clinical treatment of phlegm disorder. METHODS: The word "phlegm" was taken as the search term and the relevant articles were retrieved from Zhonghuayidian (Dictionary of Chinese Medicine). According to the inclusion and exclusion criteria, the articles were screened and the database was set up. The analysis was conducted on acupoint selection, the correlation with meridians involved and distribution location, as well as the use frequency of specific points and acupoint combination. RESULTS: It was found that in treatment of phlegm disorder, the highest frequently used acupoints were Zusanli (ST36) and Zhongwan (CV12). The use frequency of three yang meridians was higher than that of three yin meridians. The commonly involved meridians were the Conception Vessel, Bladder Meridian of Foot-taiyang and the Governor Vessel. The acupoints located in the chest and abdomen were highly used. The use frequency of specific points was higher than that of non-specific ones. The sequence of the use frequency of specific points, from high to low, is the crossing point, the front-mu point and luo-connecting point. The combination of Danzhong (CV17) and Zusanli (ST36) is of the high frequency. CONCLUSION: Ancient medical scholars focus on regulating spleen and stomach functions, as well as qi activity in treatment of phlegm disorder with acupuncture and moxibustion, which is coincident with the treatment principle of phlegm disorder in traditional Chinese medicine. In treatment, acupuncture-moxibusiton is characterized as laying the emphasis on the specific points, the local acupoints and the holistic idea as " regulation of yang for yin disorder"．.