Use of probiotics in medical devices applied to some common pathologies.

Probiotics, defined as "living microorganisms that, whether ingested in useful amount, may have beneficial effects on human body", are widely used in various products for human use, such as dietary supplements, medical devices and pharmaceutical products. The European Directive on medical devices (MDs) (DDM 93/42), also includes those MDs containing live microorganisms, particularly probiotics, that may have various destinations of use, including that of assisting the therapy of several human pathologies. In this brief note we analyzed the use of probiotics in MDs and how probiotics administration could represent one of the new frontiers of scientific research on the prevention and treatment of various diseases. We'll analyze the literature on probiotics based MDs, to review their major targets in the therapy of some of the most common human pathologies: bacterial vaginosis and vaginitis, atopic dermatitis, infantile colic, obesity, type 2 diabetes, and pharyngotonsillitis.

Mental rotation training in older adults: The role of practice and strategy.

There is evidence of mental rotation (MR) abilities responding to training even in older adults, but it is still not clear whether such training would have generalized and maintained effects. The aim of the present study was to examine the specific short- and long-term gains, and any transfer effects, induced by rotation training in healthy older adults. The study involved 43 healthy older adults: 14 practiced with 2 MR tasks, that is, a 3D same/different comparisons task and a Tetris game (the Mental Rotation [MR] group); 15 were trained to use a strategy based on concrete object manipulation and imagery, then practiced with the 2 rotation tasks (Strategy [S] + MR group); and 14 were involved in alternative nonspatial activities (active control group). Transfer and maintenance effects were assessed (after 1 month) using tasks similar to those used in the training (criterion tasks), different spatial tasks (mental rotation and perspective taking tasks) and a fluid intelligence task. The results showed a trend toward an improvement in successive training sessions. The S + MR and MR groups both gained substantially more than the active control group in the short- and long-term, in the criterion tasks and most of the tasks testing transfer effects. The S + MR group showed greater long-term gains than the MR group in most tasks. These findings support a positive effect of rotation training in older adults, particularly when associated with strategy use. (PsycINFO Database Record

Identification of aminoethylcysteine ketimine decarboxylated dimer, a natural antioxidant, in dietary vegetables.

Aminoethylcysteine ketimine decarboxylated dimer (simply named dimer) is a natural sulfur-containing tricyclic compound detected, until now, in human urine, bovine cerebellum, and human plasma. Recently, the antioxidant properties of this compound have been demonstrated. In this investigation, the presence of aminoethylcysteine ketimine decarboxylated dimer was identified in garlic, spinach, tomato, asparagus, aubergine, onion, pepper, and courgette. Identification of this compound in dietary vegetables was performed using gas chromatography, high-performance liquid chromatography, and gas chromatography-mass spectrometry. Results from GC analysis range in the order of 10(-4) micromol of dimer/g for all the tested vegetables. These results and the lack of a demonstrated biosynthetic pathway in humans might account for a dietary supply of this molecule.