RESUMO
Diseases caused by viruses are a global threat, resulting in serious medical and social problems for humanity. They are the main contributors to many minor and major outbreaks, epidemics, and pandemics worldwide. Over the years, medicinal plants have been used as a complementary treatment in a range of diseases. In this sense, this review addresses promising antiviral plants from Marajó island, a part of the Amazon region, which is known to present a very wide biodiversity of medicinal plants. The present review has been limited to articles and abstracts available in Scopus, Web of Science, Science Direct, Scielo, PubMed, and Google Scholar, as well as the patent offices in Brazil (INPI), United States (USPTO), Europe (EPO) and World Intellectual Property Organization (WIPO). As a result, some plants from Marajó island were reported to have actions against HIV-1,2, HSV-1,2, SARS-CoV-2, HAV and HBV, Poliovirus, and influenza. Our major conclusion is that plants of the Marajó region show promising perspectives regarding pharmacological potential in combatting future viral diseases.
Assuntos
Antivirais/uso terapêutico , Tratamento Farmacológico da COVID-19 , Extratos Vegetais/química , Plantas Medicinais/química , Antivirais/química , Antivirais/isolamento & purificação , Antivirais/farmacologia , Brasil , COVID-19/virologia , HIV-1/efeitos dos fármacos , Vírus da Hepatite A/efeitos dos fármacos , Herpesvirus Humano 1/efeitos dos fármacos , Humanos , Extratos Vegetais/farmacologia , Extratos Vegetais/uso terapêutico , Plantas Medicinais/metabolismo , SARS-CoV-2/efeitos dos fármacos , SARS-CoV-2/isolamento & purificaçãoRESUMO
OBJECTIVES: To assess the association of academic education in health professions programs with the knowledge and use of Complementary and Alternative Medicine (CAM) by university students and to determine whether CAM can promote a healthy university environment. METHODS: A cross-sectional study was carried out with 512 university students enrolled in health professions programs in the city of Fortaleza, Ceará, Brazil, from April to November 2017. The Assessment Tool for Health Promotion at the University was used to collect sociodemographic, academic and CAM data. Bivariate and multivariate analyses were performed considering the outcomes "knowledge of CAM" and "CAM in the promotion of a healthy university environment" using SPSS Statistic version 20.0. RESULTS: Data from 512 participants were analyzed. Women (n = 357; 69.7%), young students (n = 393; 76.8%) and unemployed students (n = 429; 83.8%) predominated. Knowledge of CAM was associated with health profession program (OR = 0.934; p = 0.047), paternal education (OR = 0.641; p = 0.024), employment (OR = 0.542; p = 0.028) and participation in extracurricular activities (OR = 1.275; p = 0.007). There was a proportional difference between knowledge and use of CAM ranging from 2:1 to 11:1 among the 21 modalities. University students believed that CAM could promote a healthy university environment (p = 0.000), which was influenced by gender (OR = 2.089; p = 0.004) and knowledge of CAM (OR = 16.601; p = 0.000). CONCLUSIONS: University students' knowledge of CAM was influenced by the health profession program, paternal education, employment and participation in extracurricular activities. The percentage of use of CAM modalities was lower than the percentage of knowledge. University students' belief that CAM could foster a healthy university environment is influenced by gender and knowledge of CAM.