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Artigo em Chinês | WPRIM | ID: wpr-321376

RESUMO

This study compared the decoction's HPLC figures of the different processed rhizomes of Cibotium barometz including the raw, the sand-baked, the wined, the steamed and the salted, on the basis of which, with the sand-baked Drynaria fortunei decoction as the positive control group, comparingall groups' decoction, concentration of which was 104.2 g x L(-1), for 4 weeks, by their effects (s-TRAP and total scores of OPG, Ca, P, IL-6, TNF-alpha and IL-1) on retinoic acid induced male rats osteoporosis. The experiment results showed the sand-baked and the wined were better than the steamed, the salted and the raw;in the processing methods' selection, the sand-baked was a better heating method than the steamed and the rice wine was the better excipient than the salt. It provided a reference to explain the processing principle of rhizomes of C. barometz and work mechanism of anti-osteoporosis.


Assuntos
Animais , Masculino , Ratos , Biomarcadores , Sangue , Cromatografia Líquida de Alta Pressão , Composição de Medicamentos , Métodos , Medicamentos de Ervas Chinesas , Química , Farmacologia , Usos Terapêuticos , Osteoporose , Sangue , Tratamento Farmacológico , Traqueófitas , Química , Ratos Sprague-Dawley , Rizoma , Química , Tretinoína
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