RESUMO
Reversed-phase preparative HPLC analyses of the methanol extract of the aerial parts of Stachys lavandulifolia afforded a new phenylethanoid glycoside, 4,3',4'-trimethoxy-lavandulifolioside A, named lavandulifolioside B, together with three other known phenylethanoid glycosides, lavandulifolioside A, verbascoside and leucosceptoside A, and an iridoid glycoside 5-O-ß-allopyranosyloxy-aucubin (5-O-ß-allopyranosyl-monomelittoside). While the structures of the known compounds, except the iridoid glycoside, were established by direct comparison of their spectroscopic data with respective literature data, lavandulifolioside B and 5-O-ß-allopyranosyloxy-aucubin were identified comprehensively by extensive 1D and 2D NMR analyses. The distribution of the isolated compounds within the genus Stachys has been discussed.
Assuntos
Glicosídeos , Glicosídeos Iridoides , Componentes Aéreos da Planta/química , Stachys/química , Glicosídeos/química , Glicosídeos/isolamento & purificação , Glicosídeos Iridoides/química , Glicosídeos Iridoides/isolamento & purificação , Espectroscopia de Ressonância Magnética , Estrutura Molecular , Extratos Vegetais/químicaRESUMO
Annotemoyin-1, Annotemoyin-2, squamocin and cholesteryl glucopyranoside were isolated from the seeds of Annona squamosa. These compounds and plant extracts showed remarkable antimicrobial and cytotoxic activities.
Assuntos
Annona , Anti-Infecciosos/farmacologia , Bactérias Gram-Negativas/efeitos dos fármacos , Bactérias Gram-Positivas/efeitos dos fármacos , Fitoterapia , Extratos Vegetais/farmacologia , Animais , Anti-Infecciosos/administração & dosagem , Anti-Infecciosos/uso terapêutico , Artemia/efeitos dos fármacos , Humanos , Dose Letal Mediana , Fungos Mitospóricos/efeitos dos fármacos , Extratos Vegetais/administração & dosagem , Extratos Vegetais/uso terapêutico , SementesRESUMO
A new C-benzylated chalcone was isolated from the leaves of Desmos chinensis. Its structure was established as 2',4'-dihydroxy-3'-(2,6-dihydroxybenzyl)-6'-methoxychalcone on the basis of spectroscopic data.
Assuntos
Annonaceae , Fitoterapia , Extratos Vegetais/química , Chalcona/química , Humanos , Folhas de PlantaRESUMO
1-Methyl-1H-pyrimidine-2,4-dione and 3-O-beta-D-glucopyranosyl-(24beta)-ethylcholesta-5,22,25-triene, isolated from the flowers of Alangium salviifolium, showed remarkable antibacterial activities against a number of Gram-positive and Gram-negative bacterial species.