RESUMO
AIM: Sacral nerve stimulation (SNS) has a place in the treatment algorithm for faecal incontinence (FI). However, after implantation, 15-30% of patients with FI fail to respond for unknown reasons. We investigated the effect of SNS on continence and quality of life (QOL) and tried to identify specific predictive factors of the success of permanent SNS in the treatment of FI. METHOD: Two hundred consecutive patients (six men; median age = 60; range 16-81) underwent permanent implantation for FI. The severity of FI was evaluated by the Cleveland Clinic Score. Quality of life was evaluated by the French version of the American Society of Colon and Rectal Surgeons (ASCRS) quality of life questionnaire (FIQL). All patients underwent a preoperative evaluation. After permanent implantation, severity and QOL scores were reevaluated after six and 12 months and then once a year. RESULTS: The severity scores were significantly reduced during SNS (P = 0.001). QOL improved in all domains. At the 6-month follow-up, the clinical outcome of the permanent implant was not affected by age, gender, duration of symptoms, QOL, main causes of FI, anorectal manometry or endoanal ultrasound results. Only loose stool consistency (P = 0.01), persistent FI even though diarrhoea was controlled by medical treatment (P = 0.004), and low stimulation intensity (P = 0.02) were associated with improved short-term outcomes. Multivariate analysis confirmed that loose stool consistency and low stimulation intensity were related to a favourable outcome. CONCLUSION: Stool consistency and low stimulation intensity have been identified as predictive factors for the short-term outcome of SNS.
Assuntos
Terapia por Estimulação Elétrica , Incontinência Fecal/terapia , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Eletrodos Implantados/efeitos adversos , Incontinência Fecal/cirurgia , Fezes , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Seleção de Pacientes , Qualidade de Vida , Análise de Regressão , Região Sacrococcígea/inervação , Índice de Gravidade de Doença , Inquéritos e Questionários , Adulto JovemRESUMO
OBJECTIVE: Since the first paper published by Matzel et al., in 1995, on the efficacy of sacral nerve stimulation (SNS) in patients with faecal incontinence, the indications, the contraindications, the stimulation technique and follow up of implanted patients have changed. The aim of this article was to provide a consensus opinion on the management of patients with faecal incontinence treated with SNS. METHOD: Recommendations were based on a critical review of the literature when available and on expert opinions in areas with insufficient evidence. RESULTS: We have reviewed the indications and contraindications, proposed an algorithm for patient management showing the place of SNS. The temporary test technique, the implantation technique, the patient follow up and the approach in case of treatment failure were discussed. CONCLUSION: We hope not only to provide a guide on patient management to clinical practitioners interested in SNS but also to harmonize our practices.
Assuntos
Canal Anal/inervação , Terapia por Estimulação Elétrica/métodos , Incontinência Fecal/terapia , Guias de Prática Clínica como Assunto , Eletrodos Implantados , Medicina Baseada em Evidências , Humanos , Região Sacrococcígea/inervaçãoRESUMO
The authors have used autotransfusion of intraoperatively collected blood in 58 vascular surgery cases over a period of more than two years. The clinical results confirm the experimental and laboratory studies on the quality of the autotransfused blood. A more liberal use of intraoperative autotransfusion is advocated. Intraoperative autotransfusion is a simple, safe, inexpensive and cost-effective technique. It saves homologous banked blood and provides a readily available, compatible, normothermic transfusate with superior hematologic qualities.
Assuntos
Transfusão de Sangue Autóloga , Humanos , Período Intraoperatório , Procedimentos Cirúrgicos VascularesAssuntos
Transfusão de Sangue Autóloga , Procedimentos Cirúrgicos Vasculares/métodos , Coleta de Amostras Sanguíneas , Transfusão de Sangue Autóloga/efeitos adversos , Transfusão de Sangue Autóloga/instrumentação , Equipamentos Descartáveis , Estudos de Avaliação como Assunto , Feminino , Humanos , Masculino , Sucção , Procedimentos Cirúrgicos Vasculares/instrumentaçãoRESUMO
This procedure is well known, there were 2 000 cases reported in the literature with a very small number of complications. Is autotransfusion really efficacious? According to the author's results in 9 cases of hemoperitoneum, the red cells obtained by this method are quantitatively valid, but hemolysis starts early (6 hours) and the disappearance of the platelets and coagulation factors occurs even more early (2 hours). However, clinical tolerance is perfect, thus confirming the good experimental results obtained in animals. The true limits are hemolysis and the risk of contamination but, with appropriate apparatus and precise indications, and unsoiled blood, less than 24 hours old, autotransfusion is a good method which may provide a solution in certain emergencies.