RESUMO
The nature of the anticoagulant isolated from the Chinese peony roots has been determined. Physicochemical analysis (infrared and mass spectroscopy, and polyacrylamide gel electrophoresis) demonstrated the presence of a glycopeptide in Paeonia suffraticosae roots. This glycopeptide shares a structural similarity with heparin.
Assuntos
Anticoagulantes/isolamento & purificação , Plantas Medicinais , Anticoagulantes/análise , Eletroforese em Gel de Poliacrilamida , Glicopeptídeos/análise , Glicopeptídeos/isolamento & purificação , Espectrometria de Massas , Peso Molecular , Raízes de Plantas , Federação Russa , Espectrofotometria InfravermelhoRESUMO
In the present work, the nature of an anticoagulant from Philipendula ulmaria was studied. A method for purification of this anticoagulant was developed. Using diverse methods it was shown that the molecular weight, data on element (sulphur, nitrogen, and hydrogen) content, spectral characteristics in the infrared region of the spectrum, and electrophoretic properties of the product indicate its similarity to heparin of animal origin.
Assuntos
Heparina/isolamento & purificação , Plantas Medicinais , Animais , Cromatografia em Gel , Eletroforese em Gel de Poliacrilamida , Heparina/análise , Heparina/farmacologia , Peso Molecular , Tempo de Tromboplastina Parcial , Ratos , Espectrometria de Massas de Bombardeamento Rápido de Átomos , Espectrofotometria Infravermelho , Tempo de TrombinaRESUMO
Psychological personality profiles were evaluated in 87 patients with bronchial asthma and chronic obstructive bronchitis treated by means of acupuncture. The data point to the improvement of psychological state and reduction of pathological types in patients that run parallel with their clinical improvement. The transition from one pathological state to another having a more benign course was also observed.
Assuntos
Asma/psicologia , Bronquite/psicologia , Transtornos Neurocognitivos/etiologia , Transtornos da Personalidade/etiologia , Adolescente , Adulto , Idoso , Asma/complicações , Asma/terapia , Bronquite/complicações , Bronquite/terapia , Broncodilatadores/uso terapêutico , Terapia Combinada , Humanos , Pessoa de Meia-Idade , Transtornos Neurocognitivos/terapia , Transtornos da Personalidade/terapia , ReflexoterapiaAssuntos
Terapia por Acupuntura , Asma/terapia , Adolescente , Adulto , Idoso , Terapia Combinada , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Fatores de TempoAssuntos
Asma/terapia , Reflexoterapia , Terapia por Acupuntura , Adolescente , Adulto , Asma/fisiopatologia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , RespiraçãoRESUMO
Activity of sympathoadrenal system in patients with infectious-allergic bronchial asthma treated with reflexotherapy by monitoring alterations in spontaneous and L-DOPA stimulated daily excretion of adrenaline, noradrenaline, dopamine and L-DOPA with urine. Before and after the reflexotherapy course spontaneous excretion of catecholamines and L-DOPA with urine was found to be similar to the physiologically normal level. The test with per oral administration of 250 mg of L-DOPA showed that before the reflexotherapy the course of consumption of L-DOPA was impaired and, hence, the functional state of sympathoadrenal system was altered. The reflexotherapy improved the L-DOPA consumption suggesting normalization of catecholamine metabolism. The data obtained suggest that normalization of sympathoadrenal system activity is one of important effects of the acupuncture therapy.