Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 2 de 2
Filtrar
Mais filtros

Base de dados
País/Região como assunto
Ano de publicação
Tipo de documento
País de afiliação
Intervalo de ano de publicação
1.
J Immunother Cancer ; 9(3)2021 03.
Artigo em Inglês | MEDLINE | ID: mdl-33771890

RESUMO

Treatment with programmed cell death 1 inhibitors is associated with a wide range of cutaneous immune-related adverse events, with lichenoid eruptions representing one of the major cutaneous toxicities. We describe the case of an 81-year-old man with metastatic melanoma treated with pembrolizumab who subsequently developed a delayed-onset generalized lichenoid dermatitis. After failing multiple lines of systemic immunosuppression, narrowband ultraviolet B (NBUVB) phototherapy three times per week for 17 sessions resulted in a significant clinical response in his cutaneous eruption and was well tolerated. NBUVB is a safe, lower-cost modality that induces local, skin-specific immunosuppression without the toxicities of traditional systemic immunosuppressive agents. To date, this is the first report of use of NBUVB in immune-related lichenoid dermatitis resistant to multiple standard therapies.


Assuntos
Anticorpos Monoclonais Humanizados/efeitos adversos , Inibidores de Checkpoint Imunológico/efeitos adversos , Erupções Liquenoides/radioterapia , Melanoma/tratamento farmacológico , Receptor de Morte Celular Programada 1/antagonistas & inibidores , Neoplasias Cutâneas/tratamento farmacológico , Terapia Ultravioleta , Idoso de 80 Anos ou mais , Humanos , Erupções Liquenoides/induzido quimicamente , Erupções Liquenoides/imunologia , Erupções Liquenoides/patologia , Masculino , Melanoma/imunologia , Melanoma/secundário , Receptor de Morte Celular Programada 1/imunologia , Neoplasias Cutâneas/imunologia , Neoplasias Cutâneas/patologia , Resultado do Tratamento
2.
J Cutan Med Surg ; 11(2): 53-6, 2007.
Artigo em Inglês | MEDLINE | ID: mdl-17374315

RESUMO

BACKGROUND: Nonattendance at scheduled appointments is a major problem. Previous studies have shown rates between 17 and 31%. Most US studies found the type of payer to be the greatest determinant of attendance rates. OBJECTIVES: This study examines the no-show rate in a private dermatology practice under a single universal payer model, including the effects of old versus new patient, gender, day of the week, month, and weather. RESULTS: The overall rate of nonattendance was lower than in all previous studies (7.79%), with the only statistically significant variable being established versus new patients. LIMITATIONS: Certain demographic data investigated in previous studies (eg, age, socioeconomic status) were not assessable. Data are from a single office. CONCLUSION: The no-show rate in a single universal payer, private practice model is low, especially for established patients.


Assuntos
Agendamento de Consultas , Dermatologia/estatística & dados numéricos , Pacientes Desistentes do Tratamento/estatística & dados numéricos , Prática Privada/estatística & dados numéricos , Sistema de Fonte Pagadora Única/estatística & dados numéricos , Dermatologia/economia , Feminino , Humanos , Masculino , Programas Nacionais de Saúde , Pacientes Desistentes do Tratamento/classificação , Prática Privada/economia , Quebeque
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA