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Vet Immunol Immunopathol ; 136(1-2): 138-43, 2010 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-20236709

RESUMO

This study evaluated the transference of maternal-specific antibodies against Haemonchus contortus and the humoral immune response of 32 goat kids to natural infection by the parasite, from birth to 5 months of age. All serum samples collected immediately after birth and before colostrum ingestion were negative for H. contortus antibodies, as demonstrated by ELISA. However, 30 and 60 days after colostrum and milk ingestion, antibody detection was positive and faecal egg count (FEC) was negative, suggesting the transference of humoral immunity by colostrum. All animals were FEC-negative for Strongylodea until four months of age, consistent with the stage of animal development where nourishment comes only from breastfeeding. Animals also presented a high serum IgA concentration, associated with lower levels of total IgG. This work demonstrated that passive humoral immunity against H. contortus in goat kids occurs via the colostrum and not by transplacental transference of antibodies.


Assuntos
Doenças das Cabras/imunologia , Hemoncose/veterinária , Haemonchus/imunologia , Imunidade Materno-Adquirida , Fatores Etários , Animais , Animais Recém-Nascidos , Anticorpos Anti-Helmínticos/sangue , Colostro/imunologia , Feminino , Doenças das Cabras/parasitologia , Cabras , Hemoncose/imunologia , Hemoncose/parasitologia , Imunidade Humoral , Imunoglobulina A/sangue , Imunoglobulina G/sangue , Imunoglobulina M/sangue , Masculino , Leite/imunologia , Contagem de Ovos de Parasitas , Gravidez
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