Increasing long-chain n-3PUFA consumption improves small peripheral artery function in patients at intermediate-high cardiovascular risk.

Dietary long-chain n-3 polyunsaturated fatty acids (LCn-3PUFA) improve endothelial function in medium-large-sized arteries, but effects on small peripheral arteries, responsible for most arterial resistance, are little known. We investigated the effects of increasing LCn-3PUFA intake with the usual diet on small artery reactive hyperemia index (saRHI). Within a clinical trial evaluating the effects of 1 year of intensive lifestyle intervention versus standard care on cardiovascular markers in subjects at risk, we selected 108 participants regardless of treatment allocation (n=47 standard care; n=61 intensive intervention) with complete baseline and follow-up information on dietary, clinical, saRHI and biochemical data, including biomarkers of inflammation and endothelial activation. At the end of follow-up, saRHI increased across tertiles of change in dietary LCn-3PUFA. Subjects in the top tertile (increased LCn-3PUFA intake) increased serum ApoA1 and decreased hs-CRP, serum TNF-α, sICAM-1, sVCAM-1 and oxLDL from baseline. After pooling data, in unadjusted models, changes in saRHI significantly correlated to changes in LCn-3PUFA intake and ApoA1 (directly) and changes in systolic blood pressure, waist circumference, TNF-α, sVCAM-1 and sE-selectin (inversely). In a multivariate model, changes in dietary LCn-3PUFA were significantly associated with changes in saRHI [B=0.08 (95% confidence interval=0.083-0.291) for an increase by 100 mg/day]. Systolic blood pressure was inversely associated with saRHI changes [B=-0.203 (-0.441 to -0.029) for a 9-mmHg increase]. We conclude that increased dietary consumption of LCn-3PUFA might be a cost-effective strategy to improve peripheral vasoactivity.

Cumplimiento de las visitas de mantenimiento periódico periodontal / Compliance with supportive periodontal therapy

las visitas de mantenimiento periodontal periódico, también llamadas de tratamiento de refuerzo periódico periodontal, son necesarias para el éxito del tratamiento periodontal Tan importante como el control de la situación periodontal es indispensable la colaboración del paciente en el cumplimiento de dichas citas Esta revisión de literatura pretende ayudar a conocer la pauta de comportamiento de los pacientes en visitas de mantenimiento y conocer las características de los pacientes que más fácilmente pueden fallar, ya que ello nos servirá para modificar esta conducta y conseguir pacientes lo más cumplidores pos eles, y por tanto con unas buenas condiciones periodontales. Los pacientes menos cumplidores son los jóvenes que no han recibido tratamiento quirurgico. Entre los factores que influyen en la falta de cumplimiento influye el tiempo pasado desde la fase activa del tratamiento, la excesiva frecuencia de las visitas, factores psicológicos y personales y la falta de información (AU)