RESUMO
Twenty-one patients with documented coronary artery disease were tested at baseline by exercise tolerance testing, and assigned to either stress reduction using the Transcendental Meditation (TM) program or to a wait-list control, After 8 months, the TM group had a 14.7% increase in exercise tolerance, an 11.7% increase in maximal workload, an 18% delay in onset of ST-segment depression, and significant reductions in rate-pressure product at 3 and 6 minutes, and at maximal exercise compared with the control group.
Assuntos
Doença das Coronárias/terapia , Meditação , Angina Pectoris/terapia , Doença das Coronárias/fisiopatologia , Doença das Coronárias/psicologia , Teste de Esforço , Hemodinâmica , Humanos , Projetos Piloto , Estudos Prospectivos , Método Simples-Cego , Estresse Psicológico , Resultado do TratamentoAssuntos
Anticorpos Monoclonais/biossíntese , Técnicas de Cultura/métodos , Anticorpos Anti-HIV/biossíntese , Proteína gp120 do Envelope de HIV/imunologia , Cadeias Pesadas de Imunoglobulinas/biossíntese , Cadeias Leves de Imunoglobulina/biossíntese , Proteínas Recombinantes de Fusão/biossíntese , Aminoácidos/análise , Animais , Anticorpos Monoclonais/genética , Citomegalovirus/genética , DNA Complementar/genética , Regulação da Expressão Gênica/efeitos dos fármacos , Genes Reporter , Genes Sintéticos , Vetores Genéticos , Glutamato-Amônia Ligase/biossíntese , Glutamato-Amônia Ligase/genética , Anticorpos Anti-HIV/genética , Humanos , Cadeias Pesadas de Imunoglobulinas/genética , Cadeias Leves de Imunoglobulina/genética , Camundongos , Plasmocitoma/patologia , Regiões Promotoras Genéticas , Proteínas Recombinantes de Fusão/genética , Células Tumorais CultivadasRESUMO
An ancient system of natural medicine--Maharishi Ayur-Vedic--prescribes certain herbal formulas to enhance cognitive functioning, prevent illness, and alleviate the detrimental effects of the aging process. A double-blind study was conducted to test the effect of an Ayurvedic herbal preparation, Maharishi Amrit Kalash (MAK), on an age-related alertness task. Forty-eight men over 35 years of age were randomly assigned to receive MAK tablets or a closely matched placebo twice daily for six weeks. A visual discrimination task consisted of the identification of the exact location of a stimulus "v" within an array of x symbols in tachistoscopic presentations. The MAK group improved significantly more in their performance of this task after three and six weeks of treatment relative to the placebo group. Performance was highly correlated with age, and because successful performance apparently requires an unrestricted flow of homogeneous attention as well as focalized concentration, it is concluded that MAK may enhance attentional capacity or alertness, and thus reverse some of the detrimental cognitive effects of aging.
Assuntos
Envelhecimento/efeitos dos fármacos , Atenção/efeitos dos fármacos , Aprendizagem por Discriminação/efeitos dos fármacos , Ayurveda , Extratos Vegetais/uso terapêutico , Percepção Visual/efeitos dos fármacos , Adulto , Humanos , Masculino , FitoterapiaRESUMO
As part of a large-scale international, co-operative investigation into the side-effects produced by thioacetazone employed in the treatment of tuberculosis, an evaluation has been made of a supplement incorporating vitamins and an antihistamine as a prophylactic.Over a 12-week period of treatment, the additive supplement failed to reduce the over-all frequency of side-effects or the frequency of side-effects leading to a major departure from prescribed treatment. There was also no evidence that the more serious side-effects, particularly rashes, jaundice and agranulocytosis, were reduced by the additives, although the occurrence of vomiting, which was however infrequent, was reduced.In view of this lack of appreciable benefit, as well as the higher cost and impaired keeping properties of tablets containing thioacetazone plus isoniazid when the supplement is added, the use of the supplement as a prophylactic cannot be recommended.