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1.
Nutr Cancer ; 75(1): 228-235, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-35938484

RESUMO

There is still no consensus in the literature regarding the role of coffee in head and neck cancer. Thus, we sought to analyze the cumulative consumption of coffee as a protective factor in the genesis of head and neck cancer in Brazil, one of the main coffee producing countries, from January 2011 to February 2017. We carried out a case-control study in 5 referral centers for head and neck cancer with 839 cases and 842 non-cancer hospital controls matched by sex, data collection center and age group. The results of logistic regression analysis showed that the cumulative consumption of >2 cups of coffee per day is an important protective factor (OR: 0.73, 95% CI: 0.5-0.9) against head and neck cancer. Smoking increased the risk by 22 times (OR: 22.19; 95% CI: 13.7-35.8) in individuals who smoke more than 50 packs per year, and the habit of ingesting more than 155 ml of alcohol per day represented approximately twice as high risk (OR: 2.20; 95% CI: 1.4-3.4). In summary, this study suggests that coffee consumption is associated with a lower chance of head and neck cancer.


Assuntos
Café , Neoplasias de Cabeça e Pescoço , Humanos , Estudos de Casos e Controles , Fatores de Proteção , Fatores de Risco , Neoplasias de Cabeça e Pescoço/epidemiologia , Neoplasias de Cabeça e Pescoço/etiologia , Neoplasias de Cabeça e Pescoço/prevenção & controle
2.
Medicine (Baltimore) ; 101(50): e31262, 2022 Dec 16.
Artigo em Inglês | MEDLINE | ID: mdl-36550825

RESUMO

BACKGROUND: Globally, pancreatic cancer is the seventh most common cause of cancer-related death in both sexes, accounting for 466,003 deaths and 495,773 new cases in 2020. The purpose of this study was to synthesize and evaluate evidence on the effects of omega-3 supplementation on the nutritional status of patients with pancreatic cancer. METHODS: This systematic review protocol will be guided by Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocols. Five databases will be searched: MEDLINE/PubMed, CENTRAL Cochrane, EMBASE, Web of Science, and SCOPUS, with no restrictions on the publication date nor language. The internal validity and risk of bias of randomized controlled trials will be assessed using the revised Cochrane Risk-Of-Bias tool for randomized trials (RoB 2), whereas the risk of bias in non-randomized studies of interventions will be evaluated using the ROBINS-I. The heterogeneity among the studies will be assessed using the I2 statistic. Based on the results of this test, we will verify whether the meta-analysis would be feasible. If feasibility would be confirmed, a random-effect model analysis will be performed. For data analysis, the calculation of the pooled effect estimates will have a 95% confidence interval, while the alpha will be set to 0.05 using the R statistical software version 4.0.4. All methodological steps of this review will be performed independently by two reviewers and will be conducted and managed in the EPPI-Reviewer Software™. RESULTS: This review may be of particular interest to researchers and clinicians, given the low survival and overall burden of patients with pancreatic cancer. Furthermore, the results of this systematic review may contribute to the development of new nutritional interventions in these patients. CONCLUSION: To the best of our knowledge, this will be the first study to critically assess the scientific evidence and estimate the effect of omega-3 supplementation on the nutritional status of patients with pancreatic cancer. The review will perform a rigorous approach, adhering to the PRISMA Statement 2020 using a comprehensive and systematic search strategy in five databases and additional sources with no time period nor language restrictions.


Assuntos
Estado Nutricional , Neoplasias Pancreáticas , Masculino , Feminino , Humanos , Viés , Suplementos Nutricionais , Revisões Sistemáticas como Assunto , Metanálise como Assunto , Neoplasias Pancreáticas
3.
Interface (Botucatu, Online) ; 25: e200511, 2021.
Artigo em Português | SES-SP, LILACS | ID: biblio-1143136

RESUMO

A tradição indiana milenar do yoga oportuniza o autoconhecimento dos indivíduos em suas possibilidades e limitações, tornando-os mais autônomos na busca de bem-estar, mais saudáveis e conscientes. O ensaio teórico, fundamentado na revisão da literatura, analisa a repercussão do yoga em algumas de suas implicações como prática de saúde na racionalidade ocidental. A apropriação do yoga pela cultura ocídua implica a compreensão do sistema capitalista sobre o modo de produzir saúde nas sociedades contemporâneas e no aprofundamento das discussões acerca de seus benefícios filosóficos e práticos na Saúde Coletiva. Esse aprendizado fundamenta o Sistema Único de Saúde (SUS) e vem consolidando o conceito ampliado de saúde por meio da criação de pontes culturais baseadas na tolerância e no respeito a sua tradição. (AU)


La tradición hindú milenaria del yoga da oportunidad al autoconocimiento de los individuos en sus posibilidades y limitaciones, haciéndolos más autónomos en la búsqueda de bienestar, más saludables y conscientes. El ensayo teórico, fundamentado en la revisión de la literatura, analiza la repercusión del yoga en algunas de sus implicaciones como práctica de salud en la racionalidad occidental. La apropiación del yoga por la cultura occidua implica la comprensión del sistema capitalista sobre el modo de producir salud en las sociedades contemporáneas y la profundización de las discusiones sobre sus beneficios filosóficos y prácticos en la salud colectiva. Ese aprendizaje fundamenta el Sistema Brasileño de Salud (SUS) y consolida el concepto ampliado de salud, a partir de la creación de puentes culturales basados en la tolerancia y respeto a su tradición. (AU)


The ancient tradition of yoga coming from India provides individuals with self-knowledge regarding their possibilities and limitations, making them more autonomous in the search for well-being, healthier and more conscious. This theoretical essay, based on the literature review, analyzes the repercussion of yoga through some of its implications as a health practice within Western rationality. The appropriation of yoga by the Western culture implies an understanding of the capitalist system regarding the way of producing health in contemporary societies, and in the deepening of discussions about its philosophical and practical benefits in public health. This construction underlies the Brazilian National Health Sytem (SUS), and helped in the consolidation of an expanded concept of health, creating cultural bridges based on tolerance and respect for its tradition. (AU)


Assuntos
Humanos , Yoga/história , Prática de Saúde Pública , Brasil , Saúde Pública , Programas Nacionais de Saúde
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