1.
Nucleic Acids Symp Ser
; (9): 21-4, 1981.
Artigo
em Inglês
| MEDLINE
| ID: mdl-7301597
RESUMO
The problems encountered in the synthesis of 5-vinyl-2'-deoxyuridine are outlined and the synthesis of 5-bromoethynyl-2'-deoxyuridine described. E-5-(2-Bromovinyl)-2'-deoxyuridine is the most potent and specific agent against some herpes viruses yet discovered; we have now synthesised the Z-isomer and this appears to be essentially biologically inert.