RESUMO
A survey programme was organised in Lucknow and Farrukhabad, two towns of Uttar Pradesh, from March 1987 to July 1987. During the survey, the common folk medicine plants used by women were recorded and Ayurvedic and Unani drug encyclopedias were consulted for the antireproductive potential of these plants. Aqueous or 90% ethanol extracts of the plants of interest were studied in rats orally dosed for 10 days after insemination with special reference to effects on foetal development. Leaf extracts of Moringa oleifera and Adhatoda vasica were 100% abortive at doses equivalent to 175 mg/kg of starting dry material. Only the flowers of Acacia arabica and Hibiscus rosa-sinensis appeared to lack teratologic potential at the doses tested.
Assuntos
Anormalidades Induzidas por Medicamentos/etiologia , Abortivos/farmacologia , Extratos Vegetais/farmacologia , Plantas Medicinais , Abortivos/toxicidade , Animais , Desenvolvimento Embrionário e Fetal/efeitos dos fármacos , Etanol/química , Feminino , Índia , Medicina Tradicional , Extratos Vegetais/toxicidade , RatosRESUMO
Dried powder of leaf extract of common Indian plant Moringa Oleifera of Moringaceae family was tested experimentally in albino rats in our laboratory for its antifertility activity. Cant per cent abortifacient activity was found when administered orally in aqueous solution at dose of 175 mg/kg body weight daily to Charles foster strain albino rats from days 5-10 post mated.