A review on the green synthesis of nanoparticles, their biological applications, and photocatalytic efficiency against environmental toxins.

Green synthesis of nanoparticles (NPs) using plant materials and microorganisms has evolved as a sustainable alternative to conventional techniques that rely on toxic chemicals. Recently, green-synthesized eco-friendly NPs have attracted interest for their potential use in various biological applications. Several studies have demonstrated that green-synthesized NPs are beneficial in multiple medicinal applications, including cancer treatment, targeted drug delivery, and wound healing. Additionally, due to their photodegradation activity, green-synthesized NPs are a promising tool in environmental remediation. Photodegradation is a process that uses light and a photocatalyst to turn a pollutant into a harmless product. Green NPs have been found efficient in degrading pollutants such as dyes, herbicides, and heavy metals. The use of microbes and flora in green synthesis technology for nanoparticle synthesis is biologically safe, cost-effective, and eco-friendly. Plants and microbes can now use and accumulate inorganic metallic ions in the environment. Various NPs have been synthesized via the bio-reduction of biological entities or their extracts. There are several biological and environmental uses for biologically synthesized metallic NPs, such as photocatalysis, adsorption, and water purification. Since the last decade, the green synthesis of NPs has gained significant interest in the scientific community. Therefore, there is a need for a review that serves as a one-stop resource that points to relevant and recent studies on the green synthesis of NPs and their biological and photocatalytic efficiency. This review focuses on the green fabrication of NPs utilizing diverse biological systems and their applications in biological and photodegradation processes.

Understanding the Potential Role of Nanotechnology in Liver Fibrosis: A Paradigm in Therapeutics.

The liver is a vital organ that plays a crucial role in the physiological operation of the human body. The liver controls the body's detoxification processes as well as the storage and breakdown of red blood cells, plasma protein and hormone production, and red blood cell destruction; therefore, it is vulnerable to their harmful effects, making it more prone to illness. The most frequent complications of chronic liver conditions include cirrhosis, fatty liver, liver fibrosis, hepatitis, and illnesses brought on by alcohol and drugs. Hepatic fibrosis involves the activation of hepatic stellate cells to cause persistent liver damage through the accumulation of cytosolic matrix proteins. The purpose of this review is to educate a concise discussion of the epidemiology of chronic liver disease, the pathogenesis and pathophysiology of liver fibrosis, the symptoms of liver fibrosis progression and regression, the clinical evaluation of liver fibrosis and the research into nanotechnology-based synthetic and herbal treatments for the liver fibrosis is summarized in this article. The herbal remedies summarized in this review article include epigallocathechin-3-gallate, silymarin, oxymatrine, curcumin, tetrandrine, glycyrrhetinic acid, salvianolic acid, plumbagin, Scutellaria baicalnsis Georgi, astragalosides, hawthorn extract, and andrographolides.