[Potassium ions accumulation in perinodal space as a regulatory factor of functional condition of myelinated nerve fibres].

On the basis of completed experimental research on intact nodes of Ranvier in isolated nerve fibres we decided that outcome in perinodal space during excitation potassium ions accumulation realized some important functions: it decreased the potassium ions outflow from axoplasma; it caused prolonged postspike depolarization; it activated action of electrogenic membranous Na-K pump; it predetermined the generation of prolonged components of posttetanic hyperpolatisation that appeared as a supplementary factor for potassium ions reabsorbing in cytoplasm; it did underlie the mechanisms of repeated and rhythmic activity and others.