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1.
PLoS One ; 18(12): e0294294, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-38100488

RESUMO

Improving sexual, reproductive, maternal, newborn, and adolescent health outcomes necessitates greater commitment to, and investments in, midwifery. To identify future research priorities to advance and strengthen midwifery, we conducted a scoping review to synthesise and report areas of midwifery that have been explored in the previous 10 years in the 11 countries of the World Health Organization's South-East Asia region. Electronic peer-reviewed databases were searched for primary peer-reviewed research published in any language, published between January 2012 and December 2022 inclusive. A total of 7086 citations were screened against the review inclusion criteria. After screening and full text review, 195 sources were included. There were 94 quantitative (48.2%), 67 qualitative (34.4%) and 31 mixed methods (15.9%) studies. The majority were from Indonesia (n = 93, 47.7%), India (n = 41, 21.0%) and Bangladesh (n = 26, 13.3%). There were no sources identified from the Democratic People's Republic of Korea or the Maldives. We mapped the findings against six priority areas adapted from the 2021 State of the World's Midwifery Report and Regional Strategic Directions for Strengthening Midwifery in the South-East Asia region (2020-2024): practice or service delivery (n = 73, 37.4%), pre-service education (n = 60, 30.8%), in-service education or continuing professional development (n = 51, 26.2%), workforce management (n = 46, 23.6%), governance and regulation (n = 21, 10.8%) and leadership (n = 12, 6.2%). Most were published by authors with affiliations from the country where the research was conducted. The volume of published midwifery research reflects country-specific investment in developing a midwifery workforce, and the transition to midwifery-led care. There was variation between countries in how midwife was defined, education pathways, professional regulation, education accreditation, governance models and scope of practice. Further evaluation of the return on investment in midwifery education, regulation, deployment and retention to support strategic decision-making is recommended. Key elements of leadership requiring further exploration included career pathways, education and development needs and regulatory frameworks to support and embed effective midwifery leadership at all levels of health service governance.


Assuntos
Tocologia , Feminino , Humanos , Gravidez , Bangladesh , Saúde Global , Pessoal de Saúde , Tocologia/educação
2.
PLoS One ; 18(11): e0289910, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37943769

RESUMO

Preconception and interconception care improves health outcomes of women and communities. Little is known about how prepared and willing Australian midwives are to provide preconception and interconception care. The aim of this study was to explore midwives' knowledge, perspectives and learning needs, and barriers and enablers to delivering preconception and interconception care. We conducted a cross-sectional exploratory study of midwives working in any Australian maternity setting. An online survey measured midwives' self-rated knowledge; education needs and preferences; attitudes towards pre and interconception care; and views on barriers, enablers; and, future service and workforce planning. Quantitative data were analysed descriptively and demographic characteristics (e.g., years of experience, model of care) associated with knowledge and attitudes regarding pre- and interconception care were examined using univariate logistic regression analysis. Qualitative data were captured through open-ended questions and analysed using inductive content analysis. We collected responses from (n = 338) midwives working across all models of care (full survey completion rate 96%). Most participants (n = 290; 85%) rated their overall knowledge about pre and interconception health as excellent, above average or average. Participants with over 11 years of experience were more likely to report above average to excellent knowledge (OR 3.11; 95% CI 1.09, 8.85). Online e-learning was the most preferred format for education on this topic (n = 244; 72%). Most (n = 257; 76%) reported interest in providing pre and interconception care more regularly and that this is within the midwifery scope of practice (n = 292; 87%). Low prioritisation in service planning was the most frequently selected barrier to providing preconception and interconception care, whereas continuity models and hybrid child health settings were reported as enablers of pre and interconception care provision. Findings revealed that midwives are prepared and willing to provide preconception and interconception care. Pre and post registration professional development; service and funding reform; and policy development are critical to enable Australian midwives' provision of pre and interconception care.


Assuntos
Tocologia , Enfermeiros Obstétricos , Criança , Feminino , Humanos , Gravidez , Enfermeiros Obstétricos/educação , Estudos Transversais , Austrália , Inquéritos e Questionários , Pesquisa Qualitativa
3.
Nurse Educ Pract ; 70: 103648, 2023 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-37121027

RESUMO

BACKGROUND: Globally, there is a call for urgent investment in nursing and midwifery education as high-quality education leads to quality care provision. This call for investment includes a 'focus on faculty', that is, development of those who teach. However, challenges in the preparation and development of faculty have been identified and include lack of recognition of ongoing development, limited pathways for career progression, inadequate provision of, or access to, faculty development opportunities and a lack of research evaluating sustained impact of programs. OBJECTIVES: The aim of this review was to identify, synthesise and report on common program content, modes of delivery and evaluation processes of faculty development programs in nursing and/or midwifery. METHODS: A scoping review was conducted following Joanna Briggs Institute guidance. A comprehensive search strategy was developed and conducted in six health and/or education focussed databases. Peer-reviewed articles, published in English in the last decade and with a primary focus on nursing and/or midwifery faculty were included in the review. References lists of included studies were searched and a search to identify relevant grey literature was conducted. Using systematic review software, titles and abstracts were reviewed by two reviewers with a third reviewer used to resolve discrepancies. Data were extracted and recorded, key characteristics were mapped and content analysis used to synthesise, analyse and report findings. RESULTS: Seventeen articles were included in the review and identified common content provided in nursing and midwifery faculty development programs. The predominant content was approaches for learning and teaching. Other common content was leadership, research and assessment practices. Modes for program delivery were most often a blend of online and face-to-face. Program evaluation was reliant on participants' self-reported measures of satisfaction and confidence and did not examine impact over time. CONCLUSIONS AND RECOMMENDATIONS: Commonalities in program content primarily focussed on learning and teaching, but also included content linked to expected professional nursing and midwifery educator competencies such as leadership and research. However, a lack of content on the key faculty activity of curriculum design was noted and should be addressed in future program development. In addition, there was a lack of evaluation on the impact of different modes of delivery. Furthermore, an over-reliance on self-reported evaluation measures and a lack of longitudinal evaluation of impact on education practice and on student experience and outcomes. Future research should include evaluation of modes of delivery and impact on faculty practice over a sustained period.


Assuntos
Tocologia , Feminino , Humanos , Gravidez , Currículo , Docentes , Aprendizagem , Avaliação de Resultados em Cuidados de Saúde
4.
Women Birth ; 35(3): e294-e301, 2022 May.
Artigo em Inglês | MEDLINE | ID: mdl-34103270

RESUMO

PROBLEM AND BACKGROUND: Caesarean section (CS) rates in Australia and many countries worldwide are high and increasing, with elective repeat caesarean section a significant contributor. AIM: To determine whether midwifery continuity of care for women with a previous CS increases the proportion of women who plan to attempt a vaginal birth in their current pregnancy. METHODS: A randomised controlled design was undertaken. Women who met the inclusion criteria were randomised to one of two groups; the Community Midwifery Program (CMP) (continuity across the full spectrum - antenatal, intrapartum and postpartum) (n=110) and the Midwifery Antenatal Care (MAC) Program (antenatal continuity of care) (n=111) using a remote randomisation service. Analysis was undertaken on an intention to treat basis. The primary outcome measure was the rate of attempted vaginal birth after caesarean section and secondary outcomes included composite measures of maternal and neonatal wellbeing. FINDINGS: The model of care did not significantly impact planned vaginal birth at 36 weeks (CMP 66.7% vs MAC 57.3%) or success rate (CMP 27.8% vs MAC 32.7%). The rate of maternal and neonatal complications was similar between the groups. CONCLUSION: Model of care did not significantly impact the proportion of women attempting VBAC in this study. The similarity in the number of midwives seen antenatally and during labour and birth suggests that these models of care had more similarities than differences and that the model of continuity could be described as informational continuity. Future research should focus on the impact of relationship based continuity of care.


Assuntos
Tocologia , Nascimento Vaginal Após Cesárea , Cesárea , Continuidade da Assistência ao Paciente , Monofosfato de Citidina , Feminino , Humanos , Recém-Nascido , Parto , Gravidez
5.
Front Neural Circuits ; 15: 639733, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-33732114

RESUMO

The prelimbic (PL) region of the medial prefrontal cortex (mPFC) has been implicated in both driving and suppressing motivated behaviors, including cocaine-seeking in rats. These seemingly opposing functions may be mediated by different efferent targets of PL projections, such as the nucleus accumbens (NAc) core and rostromedial tegmental nucleus (RMTg), which have contrasting roles in reward-seeking behaviors. We sought to characterize the anatomical connectivity differences between PL neurons projecting to NAc core and RMTg. We used conventional retrograde tracers to reveal distinct subpopulations of PL neurons projecting to NAc core vs. RMTg in rats, with very little overlap. To examine potential differences in input specificity for these two PL subpopulations, we then used Cre-dependent rabies virus (EnvA-RV-EGFP) as a monosynaptic retrograde tracer and targeted specific PL neurons via injections of retrograde CAV2-Cre in either NAc core or RMTg. We observed a similar catalog of cortical, thalamic, and limbic afferents for both NAc- and RMTg-projecting populations, with the primary source of afferent information arising from neighboring prefrontal neurons in ipsilateral PL and infralimbic cortex (IL). However, when the two subpopulations were directly compared, we found that RMTg-projecting PL neurons received a greater proportion of input from ipsilateral PL and IL, whereas NAc-projecting PL neurons received a greater proportion of input from most other cortical areas, mediodorsal thalamic nucleus, and several other subcortical areas. NAc-projecting PL neurons also received a greater proportion of contralateral cortical input. Our findings reveal that PL subpopulations differ not only in their efferent target but also in the input specificity from afferent structures. These differences in connectivity are likely to be critical to functional differences of PL subpopulations.


Assuntos
Cocaína , Núcleo Accumbens , Animais , Neurônios , Córtex Pré-Frontal , Ratos , Tegmento Mesencefálico , Tálamo
6.
Proc Natl Acad Sci U S A ; 118(5)2021 02 02.
Artigo em Inglês | MEDLINE | ID: mdl-33495328

RESUMO

Hearing the voice of God, feeling the presence of the dead, being possessed by a demonic spirit-such events are among the most remarkable human sensory experiences. They change lives and in turn shape history. Why do some people report experiencing such events while others do not? We argue that experiences of spiritual presence are facilitated by cultural models that represent the mind as "porous," or permeable to the world, and by an immersive orientation toward inner life that allows a person to become "absorbed" in experiences. In four studies with over 2,000 participants from many religious traditions in the United States, Ghana, Thailand, China, and Vanuatu, porosity and absorption played distinct roles in determining which people, in which cultural settings, were most likely to report vivid sensory experiences of what they took to be gods and spirits.


Assuntos
Cultura , Emoções , Espiritualidade , Adulto , Comparação Transcultural , Humanos
7.
Stress Health ; 36(1): 88-96, 2020 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-31874122

RESUMO

The current investigation sought to clarify mechanisms of treatment effects in mindfulness-based stress reduction (MBSR). Self-compassion and mindful awareness were assessed first as dispositional influences and then as mediators of outcome in unique models. One hundred thirty individuals participating in the 8-week MBSR intervention were recruited (73.08% female, mean age = 46.97, SD = 14.07). Measures of psychosocial well-being (Brief Stress Inventory [BSI], Perceived Stress Scale-10 [PSS]), mindful awareness (Mindful Awareness and Attention Scale [MAAS]), and self-compassion (Self-Compassion Scale [SCS]) were collected at preintervention and postintervention. Regression was conducted to examine the influence of baseline MAAS and SCS on change in PSS and BSI scores. Serial multiple mediator models were conducted separately with pre/postintervention BSI and PSS values as criterion, and preintervention/postintervention MAAS and SCS values as mediators. Higher levels of baseline self-compassion were predictive of greater reductions in PSS scores (ß = 0.16). Reductions in BSI scores were serially mediated by change in self-compassion both directly (MBSR → ΔSCS → ΔBSI ß = 0.06) and indirectly through mindful awareness (MBSR → ΔMAAS → ΔSCS → ΔBSI ß = 0.09). Results provide support for the role of self-compassion as both a predictor of treatment effect and a process through which MBSR operates. Mechanisms underlying MBSR effects appear to be unique to the outcome of interest.


Assuntos
Empatia , Atenção Plena , Qualidade de Vida , Estresse Psicológico/terapia , Adulto , Ansiedade/prevenção & controle , Depressão/prevenção & controle , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Análise de Regressão , Estresse Psicológico/prevenção & controle
8.
Women Birth ; 32(2): e182-e188, 2019 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-30042066

RESUMO

BACKGROUND: Midwives in Australia are educated through a range of routes providing flexible ways to become a midwife. Little is known about whether the route to registration impacts on mid-career experiences, in particular, whether the pathway (post-nursing pathway compared with 'direct-entry') makes any difference. AIM: The aim of this study was to explore the midwifery workforce experiences and participation in graduates six to seven years after completing either a post-nursing Graduate Diploma in Midwifery (GradDip) or an undergraduate degree, the Bachelor of Midwifery (BMid), from one university in New South Wales, Australia. METHODS: Data were collected from mid-career midwives having graduated from one NSW university from 2007-2008 using a survey. The survey included validated workforce participation instruments - the Maslach Burnout Inventory (MBI), the Practice Environment Scale-Nursing Work Index (PES-NWI) and the Perceptions of Empowerment in Midwifery Scale (PEMS). RESULTS: There were 75 respondents: 40% (n=30) Bachelor of Midwifery and 60% (n=45) GradDip graduates. The age range was 27-56 years old (mean age=36 years) Bachelor of Midwifery graduates being on average 7.6 years older than Graduate Diploma in Midwifery graduates (40 vs 33 years; p<0.01). Almost 80% (59), were currently working in midwifery. Nine of the 12 not working in midwifery (75%) planned to return. There were no differences in workforce participation measures between the two educational pathways. Working in a continuity of care model was protective in regards to remaining in the profession. CONCLUSION: Most mid-career graduates were still working in midwifery. There were no differences between graduates from the two pathways in relation to burnout, practice experiences or perceptions of empowerment.


Assuntos
Tocologia , Enfermeiros Obstétricos , Adulto , Atitude do Pessoal de Saúde , Austrália , Feminino , Humanos , Pessoa de Meia-Idade , Tocologia/educação , Tocologia/organização & administração , Tocologia/estatística & dados numéricos , Enfermeiros Obstétricos/educação , Enfermeiros Obstétricos/organização & administração , Enfermeiros Obstétricos/psicologia , Enfermeiros Obstétricos/estatística & dados numéricos , Inquéritos e Questionários , Recursos Humanos
9.
Analyst ; 143(21): 5127-5136, 2018 Oct 22.
Artigo em Inglês | MEDLINE | ID: mdl-30280166

RESUMO

A method has been developed for extracting poppy alkaloids from oily matrices, specifically lipid residues associated with archaeological ceramics. The protocol has been applied to fresh and artificially aged poppyseed oil and to residue from a Late Bronze Age Cypriot juglet in the collections of the British Museum. The juglet is of a type that has been linked with ancient trade in opium due to its poppy-head shape and wide distribution; it is a rare example of an intact vessel with contents sealed inside. Bulk analysis of the residue by GC-EI-MS and pyGC-EI-MS indicated a degraded plant oil and possible presence of papaverine. Analysis of the alkaloid extracts by HPLC-ESI-MS using both triple quadrupole and FTICR mass spectrometers detected the five primary opium alkaloids in fresh poppyseed oil and papaverine in most of the aged samples. Papaverine and thebaine were detected in the juglet residue, providing the first rigorous chemical evidence to support a link between this vessel type and opium, or at least poppies. The association of opium with oil raises new questions about the ancient purpose of the commodities within these vessels, and the low levels (ng g-1) of opiates detected in this unusually well-preserved residue shed doubt on the scope for their detection in more fragmentary ceramic remains (potsherds). Papaverine was found to exhibit challenging carryover behaviour in all the analytical methods used in this study. The phenomenon has not been reported before and should be considered in future analyses of this analyte in all application areas.


Assuntos
Cerâmica/análise , Ópio/análise , Papaverina/análise , Óleos de Plantas/análise , Extração em Fase Sólida/métodos , Tebaína/análise , Arqueologia/métodos , Cromatografia Líquida de Alta Pressão/métodos , Cromatografia Gasosa-Espectrometria de Massas/métodos , Limite de Detecção , Papaver/química , Espectrometria de Massas por Ionização por Electrospray/métodos
10.
Nurse Educ Pract ; 28: 27-33, 2018 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-28938180

RESUMO

Domestic violence is a global public health issue. Midwives are ideally placed to screen for, and respond to, disclosure of domestic violence. Qualified midwives and midwifery students report a lack of preparedness and low levels of confidence in working with women who disclose domestic violence. This paper reports the findings from an education intervention designed to increase midwifery students' confidence in working with pregnant women who disclose domestic violence. An authentic practice video and associated interactive workshop was developed to bring the 'woman' into the classroom and to provide role-modelling of exemplary midwifery practice in screening for and responding to disclosure of domestic violence. The findings demonstrated that students' confidence increased in a number of target areas, such as responding appropriately to disclosure and assisting women with access to support. Students' confidence increased in areas where responses needed to be individualised as opposed to being able to be scripted. Students appreciated visual demonstration (video of authentic practice) and having the opportunity to practise responding to disclosures through experiential learning. Given the general lack of confidence reported by both midwives and students of midwifery in this area of practice, this strategy may be useful in supporting midwives, students and other health professionals in increasing confidence in working with women who are experiencing domestic violence.


Assuntos
Violência Doméstica , Tocologia/educação , Gestantes/psicologia , Aprendizagem Baseada em Problemas , Estudantes de Enfermagem/psicologia , Feminino , Conhecimentos, Atitudes e Prática em Saúde , Humanos , Papel do Profissional de Enfermagem , Relações Enfermeiro-Paciente , Gravidez , Cuidado Pré-Natal , Inquéritos e Questionários
11.
Health Commun ; 33(4): 363-371, 2018 04.
Artigo em Inglês | MEDLINE | ID: mdl-28059573

RESUMO

A growing number of genetic tests are included in diagnostic protocols associated with many common conditions. A positive diagnosis associated with the presence of some gene versions in many instances predicts a range of possible outcomes, and the uncertainty linked to such results contributes to the need to understand varied responses and plan strategic communication. Uncertainty in illness theory (UIT; Mishel, 1988, 1990) guided the investigation of efforts to feel in control and hopeful regarding genetic testing and diagnosis for alpha-1 antitrypsin deficiency (AATD). Participants included 137 individuals with AATD recruited from the Alpha-1 Research Registry who were surveyed about their subjective numeracy, anxiety about math, spirituality, perceptions of illness unpredictability, negative affect regarding genetic testing, and coping strategies about a diagnosis. Results revealed that experiencing more fear and worry contributed both directly and indirectly to affect-management coping strategies, operating through individual perceptions of illness unpredictability. The inability to predict the symptoms and course of events related to a genetic illness and anxiety regarding math heightened fear and worry. Spirituality lessened both illness unpredictability and negative affective responses to a diagnosis. Results affirm the importance of clinician and counselor efforts to incorporate attention to patient spirituality. They also illustrate the complexity associated with strategic efforts to plan communication about the different versions of a gene's effects on well-being, when some versions align with mild health effects and others with severe effects.


Assuntos
Adaptação Psicológica , Ansiedade , Matemática , Negativismo , Espiritualidade , Incerteza , Deficiência de alfa 1-Antitripsina/diagnóstico , Adulto , Feminino , Testes Genéticos/estatística & dados numéricos , Humanos , Masculino , Pessoa de Meia-Idade , Modelos Teóricos , Inquéritos e Questionários
12.
J Clin Psychiatry ; 78(8): e1020-e1034, 2017.
Artigo em Inglês | MEDLINE | ID: mdl-28937707

RESUMO

OBJECTIVE: To provide a quantitative meta-analysis of the antidepressant effects of sleep deprivation to complement qualitative reviews addressing response rates. DATA SOURCES: English-language studies from 1974 to 2016 using the keywords sleep deprivation and depression searched through PubMed and PsycINFO databases. STUDY SELECTION: A total of 66 independent studies met criteria for inclusion: conducted experimental sleep deprivation, reported the percentage of the sample that responded to sleep deprivation, provided a priori definition of antidepressant response, and did not seamlessly combine sleep deprivation with other therapies (eg, chronotherapeutics, repetitive transcranial magnetic stimulation). DATA EXTRACTION: Data extracted included percentage of responders, type of sample (eg, bipolar, unipolar), type of sleep deprivation (eg, total, partial), demographics, medication use, type of outcome measure used, and definition of response (eg, 30% reduction in depression ratings). Data were analyzed with meta-analysis of proportions and a Poisson mixed-effects regression model. RESULTS: The overall response rate to sleep deprivation was 45% among studies that utilized a randomized control group and 50% among studies that did not. The response to sleep deprivation was not affected significantly by the type of sleep deprivation performed, the nature of the clinical sample, medication status, the definition of response used, or age and gender of the sample. CONCLUSIONS: These findings support a significant effect of sleep deprivation and suggest the need for future studies on the phenotypic nature of the antidepressant response to sleep deprivation, on the neurobiological mechanisms of action, and on moderators of the sleep deprivation treatment response in depression.


Assuntos
Depressão , Fototerapia , Privação do Sono/psicologia , Antidepressivos/uso terapêutico , Depressão/diagnóstico , Depressão/terapia , Humanos , Fototerapia/métodos , Fototerapia/psicologia , Escalas de Graduação Psiquiátrica , Técnicas Psicológicas , Estimulação Magnética Transcraniana/métodos , Resultado do Tratamento
13.
Women Birth ; 30(3): 177-183, 2017 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-28344025

RESUMO

BACKGROUND: In 1997 a group of midwifery academics, researchers and practitioners met to discuss issues of concern related to the midwifery profession in Australia. It became clear from this discussion that midwifery in Australia was lagging behind similarly developed countries and that urgent action was required. From this meeting, a plan was developed to seek funding for a major national study into midwifery education and practice standards and as such, the Australian Midwifery Action Project (AMAP) was born. DISCUSSION: This discussion paper presents an overview of a number of midwifery education and regulation changes within the framework of the recommendations from the Australian Midwifery Action Project. A key question arising from this discussion is whether our current midwifery education and regulation standards provide a fit-for-purpose workforce that ensures all women and their families receive best practice midwifery care. Over the past 20 years the Midwifery profession in Australia has undergone significant changes and developments and these changes have had, and continue to have, significant impact on midwifery education and therefore on the quality of midwifery practice in Australia. CONCLUSION: Many changes have been implemented in the nearly 20 years since AMAP was first conceived. However, many of the issues that provided the impetus for a project such as AMAP remain and are still to be resolved. The midwifery profession continues to be subsumed with nursing, it is not possible to gain accurate midwifery workforce data and, despite the development of national standards for midwifery education, wide variations in courses still exist across Australia.


Assuntos
Acreditação/normas , Bacharelado em Enfermagem/normas , Tocologia/educação , Tocologia/normas , Enfermeiros Obstétricos/educação , Enfermeiros Obstétricos/normas , Autonomia Profissional , Adulto , Austrália , Feminino , Humanos , Gravidez
14.
BMJ Open ; 7(3): e013850, 2017 03 20.
Artigo em Inglês | MEDLINE | ID: mdl-28320793

RESUMO

OBJECTIVE: There is preclinical evidence that consumption of berryfruit extract may reduce chronic airways inflammation and modify airway remodelling in allergen-induced models of lung inflammation. We investigated the effect of berryfruit extract on the fractional expired nitric oxide (FeNO), a biomarker of eosinophilic airways inflammation, in adults with steroid-naïve asthma. DESIGN: Randomised placebo-controlled cross-over double-blind trial. SETTING: Single-centre community-based trial. PARTICIPANTS: 28 steroid-naïve mild asthmatics with Feno >40 ppb, of whom 25 completed both study interventions. INTERVENTIONS: Participants were randomised to receive, according to the cross-over design, 100 mg berryfruit polyphenolic extract (BFPE) or placebo for 4 weeks, with a 4-week washout period between the interventions. PRIMARY OUTCOME MEASURE: The primary outcome variable was FeNO at 4 weeks, analysed by a mixed linear model, with a random effect for participant and baseline FeNo as a covariate. RESULTS: The mean (SD) natural logarithm transformed (ln) FeNO after 4 weeks of treatment for the BFPE and placebo groups was 4.28 (0.47) and 4.22 (0.47), respectively. The paired change from baseline mean (SD) BFPE minus placebo ln FeNO was -0.03 (0.39), N=25. The mixed linear model estimate, with baseline covariate adjustment, difference in ln FeNO, was -0.002 (95% CI -0.15 to 0.14), p=0.98. This is equivalent to a ratio of geometric mean FeNO of 1.0 (95% CI 0.86 to 1.15). CONCLUSIONS: In steroid-naïve participants with mild asthma and elevated FeNO, there was no effect of BFPE on FeNO, a biomarker of eosinophilic airways inflammation. Caution is required in the extrapolation of apparent benefit in murine models of lung eosinophilia to clinical efficacy in patients with asthma. TRIAL REGISTRATION NUMBER: ANZCTR: 12613000451707; Results.


Assuntos
Antiasmáticos/uso terapêutico , Asma/tratamento farmacológico , Frutas , Fitoterapia/métodos , Extratos Vegetais/farmacologia , Adolescente , Adulto , Idoso , Estudos Cross-Over , Método Duplo-Cego , Feminino , Volume Expiratório Forçado , Humanos , Masculino , Pessoa de Meia-Idade , Resultado do Tratamento , Adulto Jovem
15.
Women Birth ; 29(5): 465-470, 2016 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-27050200

RESUMO

BACKGROUND: In Australia, Aboriginal women and babies experience higher maternal and perinatal morbidity and mortality rates than their non-Aboriginal counterparts. Whilst midwifery led continuity of care has been shown to be safe for women and their babies, with benefits including reducing the preterm birth rate, access to this model of care in remote areas remains limited. A Midwifery Group Practice was established in 2009 in a remote city of the Northern Territory, Australia, with the aim of improving outcomes and access to midwifery continuity of care. AIM: The aim of this paper is to describe the maternal and newborn outcomes for women accessing midwifery continuity of care in a remote context in Australia. METHODS: A retrospective descriptive design using data from two existing electronic databases was undertaken and analysed descriptively. FINDINGS: In total, 763 women (40% of whom were Aboriginal) gave birth to 769 babies over a four year period. There were no maternal deaths and the rate of perinatal mortality was lower than that across the Northern Territory. Lower rates of preterm birth (6%) and low birth weight babies (5%) were found in comparison to population based data. CONCLUSION: Continuity of Midwifery Care can be effectively provided to remote dwelling Aboriginal women and appears to improve outcomes for women and their infants.


Assuntos
Parto Obstétrico/estatística & dados numéricos , Prática de Grupo , Serviços de Saúde Materna , Tocologia , Havaiano Nativo ou Outro Ilhéu do Pacífico , Complicações do Trabalho de Parto/epidemiologia , Complicações na Gravidez/epidemiologia , Resultado da Gravidez/etnologia , Adulto , Austrália/epidemiologia , Feminino , Humanos , Lactente , Recém-Nascido de Baixo Peso , Recém-Nascido , Serviços de Saúde Materna/organização & administração , Área Carente de Assistência Médica , Tocologia/métodos , Havaiano Nativo ou Outro Ilhéu do Pacífico/estatística & dados numéricos , Northern Territory , Avaliação de Processos e Resultados em Cuidados de Saúde , Gravidez , Nascimento Prematuro/etnologia , Estudos Retrospectivos
16.
J Acoust Soc Am ; 137(5): 2834, 2015 May.
Artigo em Inglês | MEDLINE | ID: mdl-25994711

RESUMO

Research into linguistic rhythm has been dominated by the idea that languages can be classified according to rhythmic templates, amenable to assessment by acoustic measures of vowel and consonant durations. This study tested predictions of two proposals explaining the bases of rhythmic typologies: the Rhythm Class Hypothesis which assumes that the templates arise from an extensive vs a limited use of durational contrasts, and the Control and Compensation Hypothesis which proposes that the templates are rooted in more vs less flexible speech production strategies. Temporal properties of segments, syllables and rhythmic feet were examined in two accents of British English, a "stress-timed" variety from Leeds, and a "syllable-timed" variety spoken by Panjabi-English bilinguals from Bradford. Rhythm metrics were calculated. A perception study confirmed that the speakers of the two varieties differed in their perceived rhythm. The results revealed that both typologies were informative in that to a certain degree, they predicted temporal patterns of the two varieties. None of the metrics tested was capable of adequately reflecting the temporal complexity found in the durational data. These findings contribute to the critical evaluation of the explanatory adequacy of rhythm metrics. Acoustic bases and limitations of the traditional rhythmic typologies are discussed.


Assuntos
Acústica , Idioma , Periodicidade , Acústica da Fala , Percepção da Fala , Qualidade da Voz , Estimulação Acústica , Adulto , Sinais (Psicologia) , Feminino , Humanos , Masculino , Inteligibilidade da Fala , Medida da Produção da Fala , Fatores de Tempo
17.
MMWR Morb Mortal Wkly Rep ; 64(6): 155-6, 2015 Feb 20.
Artigo em Inglês | MEDLINE | ID: mdl-25695322

RESUMO

In October 2014, a hospital in Connecticut notified CDC and the Connecticut Department of Public Health of a fatal case of gastrointestinal mucormycosis in a preterm infant. The infant, born at 29 weeks' gestation and weighing 1,400 grams (about 3 pounds), had developed signs and symptoms initially consistent with necrotizing enterocolitis approximately 1 week after birth. Exploratory laparotomy revealed complete ischemia of the gastrointestinal tract from the esophagus to the rectum; a portion of necrotic cecum was sent for microscopic examination. Following surgery, the infant developed multiple areas of vascular occlusion, including a large clot in the aorta, findings not usually associated with necrotizing enterocolitis. The infant died soon after. Histopathology results from the resected cecum revealed an angioinvasive fungal infection consistent with mucormycosis. Gastrointestinal mucormycosis is an extremely rare fungal infection caused by mold in the order Mucorales. It occurs predominantly in low birth weight infants, patients with diarrhea and malnutrition, and those receiving peritoneal dialysis; mortality is 85%. Local investigation revealed that the infant had received a dietary supplement, ABC Dophilus Powder, for 7 days, beginning on day 1 of life.


Assuntos
Suplementos Nutricionais/efeitos adversos , Contaminação de Alimentos , Gastroenterite/diagnóstico , Alimentos Infantis/efeitos adversos , Doenças do Prematuro/diagnóstico , Mucormicose/diagnóstico , Connecticut , Evolução Fatal , Gastroenterite/etiologia , Trato Gastrointestinal/irrigação sanguínea , Humanos , Recém-Nascido , Doenças do Prematuro/etiologia , Isquemia/diagnóstico , Isquemia/etiologia , Masculino , Mucormicose/etiologia
19.
Fam Pract ; 30(2): 197-203, 2013 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-23123436

RESUMO

BACKGROUND: Little is known about which characteristics of chiropractors and physiotherapists matter to patients and influence their preferences when seeking care. OBJECTIVE: To examine the impact of four factors (patient gender, practitioner gender, practitioner specialty-chiropractor or physiotherapist and practitioner reputation-technical ability or interpersonal skills) on patients' choice of therapist to treat low back pain. METHODS: Questionnaire-based vignette study in which participants sampled from the general population rated the likelihood of consulting eight fictional therapists. Each fictional therapist represented a different combination of the three practitioner factors (e.g. male chiropractor with reputation for good technical ability). The study was administered as a postal survey to a simple random sample of residences in one postal town in England. RESULTS: Respondents (n = 657) consistently reported that they considered a practitioner's qualifications and technical skills important when choosing either a physiotherapist or a chiropractor; and just less than a third thought it was important that a practitioner was a good listener. As hypothesized, female respondents preferred female practitioners and respondents had a general preference for physiotherapists over chiropractors. Contrary to our hypothesis, the practitioner's reputation had the largest effect on respondents' preferences and all practitioners with a reputation for technical ability were preferred over those with a reputation for interpersonal skills. CONCLUSION: Similar factors are important to patients whether they are choosing an individual chiropractor or physiotherapist; patients particularly value information about technical competence. An awareness of these factors should help primary care providers to direct patients to relevant information and support their decision-making.


Assuntos
Quiroprática , Competência Clínica , Dor Lombar/terapia , Preferência do Paciente/psicologia , Fisioterapeutas , Relações Profissional-Paciente , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Análise de Variância , Inglaterra , Feminino , Pesquisas sobre Atenção à Saúde , Humanos , Masculino , Pessoa de Meia-Idade , Preferência do Paciente/estatística & dados numéricos , Fatores Sexuais , Inquéritos e Questionários , Adulto Jovem
20.
Nurse Educ Pract ; 13(5): 471-6, 2013 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-23140801

RESUMO

Assessment is a powerful influence on learning, and can form an important strategy amongst a variety of teaching and learning approaches. Authentic assessment activities are designed to mimic the complexity of 'real world' situations that students may encounter in professional life, and require the application of a combination of skills related to knowledge, skills and attitude. We undertook a small-scale evaluation using a qualitative descriptive design to explore the feasibility and usefulness of an authentic assessment item that focused on a common clinical scenario in midwifery practice, female catheterisation. Seven third year Bachelor of Midwifery students and three teaching staff volunteered to participate in the project. During the process the students videoed the scenario for peer assessment, developed marking criteria, completed an online survey and participated in a focus group. The findings demonstrated that the students' confidence, knowledge and skills improved as a result of participating in the assessment item and they rated it positively for use in the Bachelor of Midwifery curriculum as a means of increasing real world assessment activities. It is anticipated that this learning strategy will be further refined and integrated in various ways into other clinical midwifery subjects in the midwifery curriculum.


Assuntos
Educação Baseada em Competências/métodos , Bacharelado em Enfermagem , Avaliação Educacional/métodos , Processos Grupais , Tocologia/educação , Grupo Associado , Comportamento Cooperativo , Parto Obstétrico/enfermagem , Estudos de Viabilidade , Feminino , Grupos Focais , Conhecimentos, Atitudes e Prática em Saúde , Humanos , New South Wales , Gravidez , Avaliação de Programas e Projetos de Saúde , Pesquisa Qualitativa , Cateterismo Urinário/enfermagem , Gravação em Vídeo
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