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1.
Chem Biodivers ; 20(5): e202201071, 2023 May.
Artigo em Inglês | MEDLINE | ID: mdl-37073927

RESUMO

The present study was aimed at comprehensive overviewing a phytochemically and biologically important species namely Torilis japonica (Apiaceae family). Treatment of dysentery, fever, haemorrhoids, spasm, uterine tumors, lymphadenitis, rheumatism, impotence, infertility, women's diseases, and chronic diarrhea are reported as the main folk medicinal applications of the T. japonica fruits. So far, the plant is phytochemically characterized for its diverse terpene derivatives, predominantly sesquiterpenes. The plant's fruit is a rich source of torlin, a guaiane-type sesquiterpene, possessing various potent bioactivities. To date, anticancer, anti-inflammatory, antimicrobial, antioxidant, skin photoaging activities of the plant extracts and its constituents have been evaluated. Further investigation of the plant, specifically bioassay-guided isolation and identification of its major bioactive constituents can lead to discover potential phytopharmaceutical candidates.


Assuntos
Apiaceae , Extratos Vegetais , Feminino , Humanos , Extratos Vegetais/farmacologia , Extratos Vegetais/química , Medicina Tradicional , Sesquiterpenos de Guaiano/química , Compostos Fitoquímicos/farmacologia , Apiaceae/química , Fitoterapia , Etnofarmacologia
2.
Nat Prod Res ; 35(21): 4115-4121, 2021 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-32081037

RESUMO

The essential oil components of fresh and dry aerial parts of Callistemon citrinus, monthly harvested from Iran during a year, were compared. The EO contents of dry plant samples were dramatically higher than the fresh materials. The dry sample collected in March with 1.10 ± 0.04% and fresh in August with 0.16 ± 0.01% (w/w), possessed the highest and lowest EO yields, respectively. From thirty-two identified aroma phytoconstituents, 1,8-cineole was the major compound with quantity variation of 60.01% in dry sample collected in January and 33.92% in fresh from August. In summer, the amount of α-pinene as the second predominant volatile terpenoid was raised, while dry sample in August (46.92%) was the richest. The present study explicitly demonstrates the impact of harvesting period on volatile oil contents of C. citrinus and the findings are considerable to obtain the favourite EO compositions for consuming in food and phyto-pharmaceutical industries.


Assuntos
Myrtaceae , Óleos Voláteis , Eucaliptol , Extratos Vegetais , Terpenos
3.
Mini Rev Med Chem ; 20(11): 958-974, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-31969098

RESUMO

Medicinal plants have a wide range of secondary metabolites including monoterpene. These volatile compounds are the main components of essential oils, belonging to the isoprenoid group and possessing valuable features for plants and humans. This review provides comprehensive information on chemical structures and classification of monoterpenes. It describes their biosynthesis pathways and introduces plant families and species rich in noteworthy monoterpenes. Bio-activities, pharmacological and pesticide effects as well as their mechanism of action are reported. Applications of these compounds in various industries are also included.


Assuntos
Anti-Infecciosos/farmacologia , Antineoplásicos Fitogênicos/farmacologia , Antioxidantes/farmacologia , Monoterpenos/farmacologia , Óleos Voláteis/química , Praguicidas/farmacologia , Anti-Infecciosos/química , Anti-Infecciosos/metabolismo , Antineoplásicos Fitogênicos/química , Antineoplásicos Fitogênicos/metabolismo , Antioxidantes/química , Antioxidantes/metabolismo , Humanos , Estrutura Molecular , Monoterpenos/química , Monoterpenos/metabolismo , Praguicidas/química , Praguicidas/metabolismo
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