RESUMO
A 68-year-old man developed strabismus after having sub-Tenon's anesthesia for cataract extraction and intraocular lens implantation. An ipsilateral hypertropia with superior oblique muscle paresis developed in the operated eye. The hypertropia appeared 1 day after surgery and resolved 1 month later. Although sub-Tenon's anesthesia is considered safer than other methods of local anesthesia, strabismus may occur.
Assuntos
Anestesia Local/efeitos adversos , Extração de Catarata , Tecido Conjuntivo , Oftalmoplegia/etiologia , Idoso , Anestesia Local/métodos , Humanos , Implante de Lente Intraocular , Masculino , Oftalmoplegia/fisiopatologia , Estrabismo/etiologia , Estrabismo/fisiopatologiaRESUMO
A new treatment for myopia, biofeedback training for control of accommodation, has been proposed and developed over the past decade. Various reports in the literature show marked inconsistencies in the results of such treatment. A double-masked study with experimental and control groups of 15 subjects each was designed to obtain a definitive answer concerning the efficacy of this method. The parameters evaluated were visual acuity, cycloplegic and noncycloplegic retinoscopy, subjective refraction, amplitude of accommodation, and flexibility of accommodation. In all categories no significant difference was found between the control and experimental subjects. The consequences of these findings are discussed as to the benefit of treatments using this method and avenues to explore in future studies.
Assuntos
Acomodação Ocular/fisiologia , Biorretroalimentação Psicológica , Miopia/fisiopatologia , Adulto , Método Duplo-Cego , Feminino , Humanos , Masculino , Miopia/prevenção & controle , Prognóstico , Refração Ocular , Acuidade Visual , Percepção VisualRESUMO
Phosphoramidon (N-(alpha-L-rhamnopyranosyloxyhydroxyphosphinyl)-L-leucyl-L-trypto phan) is a powerful inhibitor of Pseudomonas aeruginosa elastase. The addition of this compound to an elastase solution injected intrastromally in rabbit eyes protected the corneas from the damage of the enzyme for a period of 12 hours. Phosphoramidon is comparable in this respect to the inhibitor 2-mercaptoacetyl-L-phenylalanyl-L-leucine, but is considerably more effective than its analog phosphoryl-L-leucyl-L-phenylalanine (P-Leu-Phe). It is suggested that the rhamnopyranosyl moiety, present in phosphoramidon but not in P-Leu-Phe, is responsible for the difference in the intracorneal activity of the two phosphoramidates. Phosphoramidon as well as the mercaptoacetyl derivative might prove beneficial in the treatment of Pseudomonas aeruginosa corneal infections.